GABA transaminase inhibitor
Encyclopedia
A GABA transaminase inhibitor is an enzyme inhibitor
that acts upon GABA transaminase.
Examples include vigabatrin
and ethanolamine-O-sulfate
(EOS).
Certain members of this class are used as anticonvulsant
s.
There is some evidence that Melissa officinalis (lemon balm) inhibits GABA transaminase.
Enzyme inhibitor
An enzyme inhibitor is a molecule that binds to enzymes and decreases their activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and pesticides...
that acts upon GABA transaminase.
Examples include vigabatrin
Vigabatrin
Vigabatrin is an antiepileptic drug that inhibits the catabolism of gamma-aminobutyric acid by irreversibly inhibiting GABA transaminase. It is an analog of GABA, but it is not a receptor agonist...
and ethanolamine-O-sulfate
Ethanolamine-O-sulfate
Ethanolamine-O-sulfate is an ester of sulfuric acid and ethanolamine. EOS is a GABA transaminase inhibitor which prevents the metabolism of GABA. It is used as a biochemical tool in studies involving GABA....
(EOS).
Certain members of this class are used as anticonvulsant
Anticonvulsant
The anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder, since many seem to act as mood stabilizers, and in the treatment of neuropathic pain. The goal of an...
s.
There is some evidence that Melissa officinalis (lemon balm) inhibits GABA transaminase.