Flavonolignan
Encyclopedia

Examples

Flavonolignans identified in Silybum marianum (milk thistle) silymarin complex include silibinin
Silibinin
Silibinin , also known as silybin, is the major active constituent of silymarin, standardized extract of the milk thistle seeds, containing mixture of flavonolignans consisting of among others of silibinin, isosilibinin, silicristin and silidianin. Silibinin itself is mixture of two diastereomers...

, silychristin, silydianin, dehydrosilybin, deoxysilycistin, deoxysilydianin, silandrin, silybinome, silyhermin and neosilyhermin and can be produced in vitro. Silibinin
Silibinin
Silibinin , also known as silybin, is the major active constituent of silymarin, standardized extract of the milk thistle seeds, containing mixture of flavonolignans consisting of among others of silibinin, isosilibinin, silicristin and silidianin. Silibinin itself is mixture of two diastereomers...

 is found in the roots of S. marianum while silyamandin can be found in the fruit.

Hydnocarpin can be found naturally in Onopordon corymbosum and can be synthetised.

Scutellaprostin A, B, C, D, E and F can be isolated from Scutellaria prostrata and can also be synthesized.

Hydnowightin can be isolated from Hydnocarpus wightiana
Hydnocarpus wightiana
Hydnocarpus wightiana or Chaulmoogra is a tree in the Achariaceae family. The oil from its seeds has been widely used in Indian medicine and Chinese traditional medicine for the treatment of leprosy. It entered early Western medicine in the ninteenth century before the era of sulfones and...

 seeds.

Three flavonolignans derived from the flavone tricin
Tricin
Tricin is a chemical compound. It is an O-methylated flavone, a type of flavonoid. It can be found in the rice bran.-Glycosides:* Tricin 4'-glucoside...

 have been isolated from the herb Avena sativa.

Palstatin has been isolated from the Amazon tree Hymeneae palustris.

Salcolin A and salcolin B can be found in Salsola collina.

Rhodiolin, the product of the oxidative coupling of coniferyl alcohol
Coniferyl alcohol
Coniferyl alcohol is an organic compound. This colourless crystalline solid is a phytochemical, one of the monolignols. It is synthethized via the phenylpropanoid biochemical pathway. When copolymerized with related aromatic compounds, coniferyl alcohol forms lignin or lignans...

 with the 7,8-dihydroxy grouping of the flavonol herbacetin
Herbacetin
Herbacetin is a flavonol, a type of flavonoid.-Glycoside and other related compounds :Herbacetin diglucoside can be isolated from flaxseed hulls....

, can be found in the rhizome of Rhodiola rosea
Rhodiola rosea
Rhodiola rosea is a plant in the Crassulaceae family that grows in cold regions of the world. These include much of the Arctic, the mountains of Central Asia, the Rocky Mountains, and mountainous parts of Europe, such as the Alps, Pyrenees, Carpathian Mountains, Scandinavia, Iceland, Great...

.

Glycosides

The flavonolignans tricin 4'-O-(erythro-beta-guaiacylglyceryl) ether and tricin 4'-O-(threo-beta-guaiacylglyceryl) ether can be isolated together with their 7-O-glucosides in the leaves of Hyparrhenia hirta
Hyparrhenia hirta
Hyparrhenia hirta is a species of grass known by the common names common thatching grass and Coolatai grass. It is native to much of Africa and Eurasia, and it is known on other continents as an introduced species. In eastern Australia it is a tenacious noxious weed. In South Africa, where it is...

.
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