Endodeoxyribonucleases
Encyclopedia
Endodeoxyribonucleases are enzymes which are both deoxyribonuclease
s and endonuclease
s.
They are classified with EC number
s 3.1.21 through 3.1.25.
Examples include:
Deoxyribonuclease
A deoxyribonuclease is any enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone. Thus, deoxyribonucleases are one type of nuclease...
s and endonuclease
Endonuclease
Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain, in contrast to exonucleases, which cleave phosphodiester bonds at the end of a polynucleotide chain. Typically, a restriction site will be a palindromic sequence four to six nucleotides long. Most...
s.
They are classified with EC number
EC number
The Enzyme Commission number is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze....
s 3.1.21 through 3.1.25.
Examples include:
- DNA restriction enzymes
- micrococcal nucleaseMicrococcal nucleaseMicrococcal Nuclease is an endo-exonuclease that preferentially digests single-stranded nucleic acids.The rate of cleavage is 30 times greater at the 5' side of A or T than at G or C and results in the production of mononucleotides and oligonucleotides with terminal 3'-phosphates...