All Topics  
Endocrine system

 

   Email Print
   Bookmark   Link






 

Endocrine system



 
 
The endocrine system is a system of small organs that involve the release of extracellular
Extracellular

In cell biology, molecular biology and related fields, the word extracellular means "outside the cell ". This space is usually taken to be outside the plasma membranes, and occupied by fluid....
 signaling molecules known as hormone
Hormone

Hormones are chemicals released by cells that affect cells in other parts of the body. Only a small amount of hormone is required to alter cell metabolism....
s. The endocrine system is instrumental in regulating metabolism
Metabolism

Metabolism is the set of chemical reactions that occur in living organisms in order to maintain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments....
, growth, development and puberty
Human development (biology)

Human development is the process of growing to maturity. In biological terms, this entails growth from a one-celled zygote to an adult human being....
, and tissue function and also plays a part in determining mood
Mood (psychology)

A mood is a relatively long lasting, affective or emotional state. Moods differ from simple emotions in that they are less specific, less intense, and less likely to be triggered by a particular stimulus or event....
. The field of studies that deals with disorders of endocrine glands is endocrinology, a branch of the wider field of internal medicine.
endocrine system is an information signal system much like the nervous system
Nervous system

The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
.






Discussion
Ask a question about 'Endocrine system'
Start a new discussion about 'Endocrine system'
Answer questions from other users
Full Discussion Forum



Recent Posts









Encyclopedia


Illu Endocrine System
The endocrine system is a system of small organs that involve the release of extracellular
Extracellular

In cell biology, molecular biology and related fields, the word extracellular means "outside the cell ". This space is usually taken to be outside the plasma membranes, and occupied by fluid....
 signaling molecules known as hormone
Hormone

Hormones are chemicals released by cells that affect cells in other parts of the body. Only a small amount of hormone is required to alter cell metabolism....
s. The endocrine system is instrumental in regulating metabolism
Metabolism

Metabolism is the set of chemical reactions that occur in living organisms in order to maintain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments....
, growth, development and puberty
Human development (biology)

Human development is the process of growing to maturity. In biological terms, this entails growth from a one-celled zygote to an adult human being....
, and tissue function and also plays a part in determining mood
Mood (psychology)

A mood is a relatively long lasting, affective or emotional state. Moods differ from simple emotions in that they are less specific, less intense, and less likely to be triggered by a particular stimulus or event....
. The field of studies that deals with disorders of endocrine glands is endocrinology, a branch of the wider field of internal medicine.

Function

The endocrine system is an information signal system much like the nervous system
Nervous system

The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
. However, the nervous system uses nerves to conduct information, whereas the endocrine system mainly uses blood vessels as information channels. Glands located in many regions of the body release into the bloodstream specific chemical messengers called hormones. Hormones regulate the many and varied functions of an organism, e.g., mood
Mood (psychology)

A mood is a relatively long lasting, affective or emotional state. Moods differ from simple emotions in that they are less specific, less intense, and less likely to be triggered by a particular stimulus or event....
, growth and development
Human development (biology)

Human development is the process of growing to maturity. In biological terms, this entails growth from a one-celled zygote to an adult human being....
, tissue function, and metabolism
Metabolism

Metabolism is the set of chemical reactions that occur in living organisms in order to maintain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments....
, as well as sending messages and acting on them.

Types of signaling

The typical mode of cell signaling
Cell signaling

Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis....
 in the endocrine system is endocrine signaling. However, there are also other modes, i.e., paracrine, autocrine, and neuroendocrine signaling. Purely neurocrine signaling between neurons, on the other hand, belongs completely to the nervous system
Nervous system

The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
.

Endocrine
the endocrine system is made up of a series of ductless glands that produce chemical messages called hormones A number of glands that signal each other in sequence is usually referred to as an axis, for example, the hypothalamic-pituitary-adrenal axis
Hypothalamic-pituitary-adrenal axis

The hypothalamic-pituitary-adrenal axis , also known as thelimbic-hypothalamic-pituitary-adrenal axis , is a complex set of direct influences and feedback interactions among the hypothalamus , the pituitary gland , and the adrenal glands ....
.

Typical endocrine glands are the pituitary, thyroid
Thyroid

The thyroid is one of the largest endocrine glands in the body. This gland is found in the neck inferior to the thyroid cartilage and at approximately the same level as the cricoid cartilage....
, and adrenal glands. Features of endocrine glands are, in general, their ductless nature, their vascularity, and usually the presence of intracellular vacuoles or granules storing their hormones. In contrast, exocrine gland
Exocrine gland

Exocrine glands are glands that secrete their products into duct s . They are the counterparts to endocrine glands, which secrete their products directly into the bloodstream or release hormones that affect only target cells nearby the release site....
s, such as salivary gland
Salivary gland

The salivary glands in mammals are exocrine glands that produce saliva. They also secrete amylase, an enzyme that breaks down starch into glucose. In other organisms such as Insecta, salivary glands are often used to produce biologically important proteins like silk or glues, and fly salivary glands contain polytene chromosomes that have been usefu...
s, sweat gland
Sweat gland

The skin contains two different groups of sweat glands: apocrine sweat glands and merocrine sweat glands. Both gland types contain myoepithelial cells , specialized epithelial cells located between the gland cells and the underlying basal lamina....
s, and glands within the gastrointestinal tract
Gastrointestinal tract

The digestive tract is the system of Organ s within multicellular animals that takes in food, digestion it to extract energy and nutrients, and expels the remaining waste....
, tend to be much less vascular and have ducts or a hollow lumen
Lumen (anatomy)

A lumen in biology is the inside space of a tubular structure, such as an artery or intestine. By extension, a lumen can also be the inside space of a cellular component or structure, such as the endoplasmic reticulum....
.

Autocrine
Other signaling can target the same cell.

Paracrine
Paracrine signaling is where the target cell is nearby.

Juxtacrine
Juxtacrine signals are transmitted along cell membranes via protein or lipid components integral to the membrane and are capable of affecting either the emitting cell or cells immediately adjacent.

Role in disease

Diseases of the endocrine system are common, including conditions such as diabetes mellitus
Diabetes mellitus

Diabetes mellitus , often referred to simply as diabetes , is a syndrome of disordered metabolism, usually due to a combination of genetic disorder and environmental causes, resulting in abnormally high blood sugar levels ....
, thyroid
Thyroid

The thyroid is one of the largest endocrine glands in the body. This gland is found in the neck inferior to the thyroid cartilage and at approximately the same level as the cricoid cartilage....
 disease, and obesity
Obesity

Obesity is a condition in which excess body fat has accumulated to an extent that health may be negatively affected. It is commonly defined as a body mass index of 30 kg/m2 or higher....
. Endocrine disease is characterized by dysregulated hormone release (a productive pituitary adenoma
Pituitary adenoma

Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 10% of intracranial neoplasia. They often remain undiagnosed, and small pituitary tumors have an estimated prevalence of 16.7% ....
), inappropriate response to signaling (hypothyroidism
Hypothyroidism

Hypothyroidism is the disease state in humans and in animals caused by insufficient production of thyroid hormone by the thyroid gland. Cretinism is a form of hypothyroidism found in infants....
), lack or destruction of a gland (diabetes mellitus type 1
Diabetes mellitus type 1

Diabetes mellitus type 1 is a form of diabetes mellitus. Type 1 diabetes is an autoimmune disease that results in destruction of insulin-producing beta cells of the pancreas....
, diminished erythropoiesis
Erythropoiesis

Erythropoiesis is the process by which red blood cells are produced. In human adults, this usually occurs within the bone marrow. In the early fetus, erythropoiesis takes place in the mesodermal cells of the yolk sac....
 in chronic renal failure
Chronic renal failure

Chronic kidney disease , also known as chronic renal disease, is a progressive loss of kidney over a period of months or years. The symptoms of worsening kidney function are unspecific, and might include feeling malaise and experiencing a anorexia....
), or structural enlargement in a critical site such as the neck (toxic multinodular goitre
Toxic multinodular goitre

Toxic multinodular goitre is a form of hyperthyroidism - where there is excess production of thyroid hormones. It is characterized by functionally autonomous nodules....
). Hypofunction of endocrine glands can occur as a result of loss of reserve, hyposecretion, agenesis
Agenesis

In medicine, agenesis refers to the failure of an Organ to develop during embryo growth and development. Many forms of agenesis are referred to by individual names, depending on the organ affected:...
, atrophy, or active destruction. Hyperfunction can occur as a result of hypersecretion, loss of suppression, hyperplastic
Hyperplasia

Hyperplasia is a general term referring to the proliferation of cells within an organ or tissue beyond that which is ordinarily seen . Hyperplasia may result in the gross enlargement of an organ, the formation of a benign tumor, or may be visible only histology....
 or neoplastic change, or hyperstimulation.

Endocrinopathies are classified as primary, secondary, or tertiary. Primary endocrine disease inhibits the action of downstream glands. Tertiary endocrine disease is associated with dysfunction of the hypothalamus and its releasing hormones.

Cancer can occur in endocrine glands, such as the thyroid
Thyroid cancer

Thyroid cancer refers to any of four kinds of cancer tumors of the thyroid gland: papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer or anaplastic thyroid cancer....
, and hormones have been implicated in signaling distant tissues to proliferate, for example, the estrogen receptor
Estrogen receptor

Estrogen receptor refers to a group of receptor s which are activated by the hormone estrogen . Two types of estrogen receptor exist: ER which is a member of the nuclear receptor family of intracellular receptors and the estrogen G protein coupled receptor GPR30 , which is a G-protein coupled receptor....
 has been shown to be involved in certain breast cancer
Breast cancer

Breast cancer is a cancer that starts in the Cell of the breast in women and men. Worldwide, breast cancer is the second most common type of cancer after lung cancer and the fifth most common cause of cancer death....
s. Endocrine, paracrine, and autocrine signaling have all been implicated in proliferation, one of the required steps of oncogenesis.

Table of endocrine glands and secreted hormones


This is a table of the glands of the endocrine system
Endocrine system

The endocrine system is a system of small organs that involve the release of extracellular signaling molecules known as hormones. The endocrine system is instrumental in regulating metabolism, human development , and tissue and also plays a part in determining Mood ....
, and their secreted hormones.

Hypothalamus
Hypothalamus

The hypothalamus is a portion of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland ....

Secreted hormone Abbreviation From cells Effect
Thyrotropin-releasing hormone
Thyrotropin-releasing hormone

Thyrotropin-releasing hormone , also called thyrotropin-releasing factor , thyroliberin or protirelin, is a tropic hormone peptide hormone that stimulates the release of thyroid-stimulating hormone and prolactin by the anterior pituitary....
TRH Parvocellular neurosecretory neurons Release thyroid-stimulating hormone
Thyroid-stimulating hormone

Thyroid-stimulating hormone is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
 (primarily)
Stimulate prolactin
Prolactin

Prolactin or Luteotropic hormone is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed....
 release from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
.
Gonadotropin-releasing hormone
Gonadotropin-releasing hormone

Gonadotropin-releasing hormone , also known as Luteinizing-hormone releasing hormone , is a tropic hormone peptide hormone responsible for the release of follicle-stimulating hormone and luteinizing hormone from the anterior pituitary....
GnRH Neuroendocine cells of the Preoptic area
Preoptic area

The preoptic area is a region of the hypothalamus. According to the MeSH classification, it is considered part of the anterior hypothalamus....
 
Release of FSH
Follicle-stimulating hormone

Follicle-stimulating hormone is a hormone synthesized and secreted by gonadotropes in the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body....
 and LH
Luteinizing hormone

Luteinizing hormone is a hormone produced by the anterior pituitary gland.* In the female, an acute rise of LH ? the LH surge ? triggers ovulation....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
.
Growth hormone-releasing hormone GHRH Neuroendocrine neurons of the Arcuate nucleus
Arcuate nucleus

The arcuate nucleus is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence. The arcuate nucleus includes several important populations of neurons, including: Neuroendocrine neurons, Centrally-projecting neurons and Others....
 
Release GH
Growth hormone

Growth hormone is a peptide hormone. It stimulates human development and cell reproduction in humans and other animals. It is a 191-amino acid, single chain polypeptide hormone which is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
Corticotropin-releasing hormone
Corticotropin-releasing hormone

Corticotropin-releasing hormone , originally named corticotropin-releasing factor , and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress ....
CRH Parvocellular neurosecretory neurons Release ACTH
Adrenocorticotropic hormone

Adrenocorticotropic hormone is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress ....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
Oxytocin
Oxytocin

Oxytocin is a mammalian hormone that also acts as a neurotransmitter in the brain.It is best known for its roles in female reproduction: it is released in large amounts after distension of the cervix and vagina during labor, and after stimulation of the nipples, facilitating childbirth and breastfeeding, respectively....
Magnocellular neurosecretory cell
Magnocellular neurosecretory cell

Magnocellular neurosecretory cells are large cell s within the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are also found in smaller numbers in accessory cell groups between these two nuclei, the largest one being the nucleus circularis....
s
Contraction of cervix
Cervix

The cervix is the lower, narrow portion of the uterus where it joins with the top end of the vagina. It is cylindrical or conical in shape and protrudes through the upper anterior vaginal wall....
 and vagina
Vagina

The vagina is a fibromuscular cylinder tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles....
Involved in orgasm
Orgasm

An orgasm is the conclusion of the Human sexual response cycle#Plateau phase of Human sexual response cycle, and may be experienced by both males and females....
, trust between people. and circadian homeostasis (body temperature, activity level, wakefulness). release breast milk
Vasopressin
Vasopressin

Arginine vasopressin , also known as vasopressin, argipressin or antidiuretic hormone , is a hormone found in most mammals, including humans....
ADH or AVP Parvocellular neurosecretory neurons Increases permeability of distal convoluted tubule and collecting duct to water in the nephrons of the kidney, thus increasing water reabsorbtion.
Somatostatin
Somatostatin

Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones....
, also growth hormone-inhibiting hormone
SS or GHIH Neuroendocrine cells of the Periventricular nucleus
Periventricular nucleus

The Periventricular nucleus is a composite structure of the hypothalamus.It should not be confused with the paraventricular nucleus....
 
Inhibit release of GH
Growth hormone

Growth hormone is a peptide hormone. It stimulates human development and cell reproduction in humans and other animals. It is a 191-amino acid, single chain polypeptide hormone which is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland....
 and TSH
Thyroid-stimulating hormone

Thyroid-stimulating hormone is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
Prolactin inhibiting hormone or Dopamine
Dopamine

Dopamine is a neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the human brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors ? D1, D2, D3, D4 and D5, and their variants....
PIH or DA Dopamine neurons of the arcuate nucleus
Arcuate nucleus

The arcuate nucleus is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence. The arcuate nucleus includes several important populations of neurons, including: Neuroendocrine neurons, Centrally-projecting neurons and Others....
 
Inhibit release of prolactin
Prolactin

Prolactin or Luteotropic hormone is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed....
 and TSH
Thyroid-stimulating hormone

Thyroid-stimulating hormone is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
Prolactin-releasing hormone PRH Release prolactin
Prolactin

Prolactin or Luteotropic hormone is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed....
 from anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....


Pineal body (epiphysis)

Secreted hormone From cells Effect
Melatonin
Melatonin

Melatonin , also known chemically as N-acetyl-5-methoxytryptamine, is a naturally occurring hormone found in most animals, including humans, and some other living organisms, including algae....
 (Primarily)
Pinealocytes antioxidant
Antioxidant

An antioxidant is a molecule capable of slowing or preventing the Redox of other molecules. Oxidation is a chemical reaction that transfers electrons from a substance to an oxidizing agent....
 and causes drowsiness


Pituitary gland
Pituitary gland

The pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing 0.5 g . It is a protrusion off the bottom of the hypothalamus at the base of the brain, and rests in a small, bony cavity covered by a Dura mater fold ....
 (hypophysis)


Anterior pituitary
Anterior pituitary

The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....
 lobe (adenohypophysis)
Secreted hormone Abbreviation From cells Effect
Growth hormone
Growth hormone

Growth hormone is a peptide hormone. It stimulates human development and cell reproduction in humans and other animals. It is a 191-amino acid, single chain polypeptide hormone which is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland....
GH Somatotrope
Somatotrope

Somatotropes are cells in the anterior pituitary which produce growth hormone. These cells constitute 30-40% of anterior pituitary cells. They respond by releasing HGH in response to GHRH or are inhibited by GHIH , both received from the hypothalamus via the hypophyseal portal system vein and the secondary plexus....
s
stimulates growth
Human development (biology)

Human development is the process of growing to maturity. In biological terms, this entails growth from a one-celled zygote to an adult human being....
 and cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 reproduction Release Insulin-like growth factor 1
Insulin-like growth factor 1

Insulin-like growth factor 1 that was once called somatomedin C, is a polypeptide protein hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have Anabolism in adults....
 from liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....
Prolactin
Prolactin

Prolactin or Luteotropic hormone is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed....
PRL Lactotropes milk production in mammary glands
sexual gratification
Orgasm

An orgasm is the conclusion of the Human sexual response cycle#Plateau phase of Human sexual response cycle, and may be experienced by both males and females....
 after sexual acts
Human sexual behavior

Human sexual behavior or human sexual practices refers to the manner in which humans experience and express their human sexuality. It encompass a wide range of activities such as strategies to find or attract partners , interactions between individuals, physical intimacy or emotional intimacy, and sexual contact....
Adrenocorticotropic hormone
Adrenocorticotropic hormone

Adrenocorticotropic hormone is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress ....
 or corticotropin
ACTH Corticotrope
Corticotrope

Corticotropes are cell in the anterior pituitary which produce adrenocorticotrophic hormone and melanocyte stimulating hormone....
s
synthesis of corticosteroid
Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiology systems such as stress , immune system and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior....
s (glucocorticoid
Glucocorticoid

Glucocorticoids are a class of steroid hormones which bind to the glucocorticoid receptor , which is present in almost every animal cell.GCs are part of the feedback mechanism in the immune system which turns immune activity down....
s and androgen
Androgen

Androgen is the generic term for any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors....
s) in adrenocortical cells
Adrenal cortex

Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively....
Lipotropin
Lipotropin

Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin . The anterior pituitary produces the pro-hormone POMC, which undergoes cleavage to Adrenocorticotropic hormone and ?-lipotropin ....
Corticotrope
Corticotrope

Corticotropes are cell in the anterior pituitary which produce adrenocorticotrophic hormone and melanocyte stimulating hormone....
s
lipolysis
Lipolysis

Lipolysis is the breakdown of fat stored in fat cells. During this process, free fatty acids are released into the bloodstream and circulate throughout the body....
 and steroidogenesis,
stimulates melanocytes to produce melanin
Melanin

Melanin is a class of compounds found in the plant, animal, and protista kingdom , where it serves predominantly as a pigment. The class of pigments are derivatives of the amino acid tyrosine....
Thyroid-stimulating hormone
Thyroid-stimulating hormone

Thyroid-stimulating hormone is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland....
 or thyrotropin
TSH Thyrotrope
Thyrotrope

Thyrotropes are cells in the anterior pituitary which produce thyroid stimulating hormone....
s
stimulates thyroid gland to secrete thyroxine
Thyroxine

Thyroxine, or 3,5,3',5'-tetra?iodothyronine , a form of thyroid hormones is the major hormone secreted by the follicular cells of the thyroid gland....
 (T4) and triiodothyronine
Triiodothyronine

Triiodothyronine, carbonhydrogeniodinenitrogenoxygen, also known as T3, is a thyroid hormone.Thyroid-stimulating hormone activates the production of thyroxine and T3....
 (T3)
Follicle-stimulating hormone
Follicle-stimulating hormone

Follicle-stimulating hormone is a hormone synthesized and secreted by gonadotropes in the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body....
FSH Gonadotrope
Gonadotrope

Gonadotropes are basophilic cell in the anterior pituitary which produce the gonadotropins follicle-stimulating hormone and luteinizing hormone ....
s
In female: stimulates maturation of Graafian follicles in ovary
Ovary

The ovary is an ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in females are homology to testicle in males, in that they are both gonads and endocrine glands....
. In male: spermatogenesis
Spermatogenesis

Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa. Spermatozoa are the mature male gametes in many sexually reproducing organisms....
, enhances production of androgen-binding protein by the Sertoli cell
Sertoli cell

A Sertoli cell is a 'nurse' cell of the testicle which is part of a seminiferous tubule.It is activated by follicle-stimulating hormone, and has FSH-receptor on its membranes....
s of the testes
Luteinizing hormone
Luteinizing hormone

Luteinizing hormone is a hormone produced by the anterior pituitary gland.* In the female, an acute rise of LH ? the LH surge ? triggers ovulation....
LH Gonadotrope
Gonadotrope

Gonadotropes are basophilic cell in the anterior pituitary which produce the gonadotropins follicle-stimulating hormone and luteinizing hormone ....
s
In female: ovulation
Ovulation

Ovulation is the process in the menstrual cycle by which a mature ovarian follicle ruptures and discharges an ovum that participates in reproduction....
In male: stimulates Leydig cell
Leydig cell

Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testes. They can secrete testosterone and are often closely related to nerves....
 production of testosterone
Testosterone

Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testis of males and the ovaries of females, although small amounts are also secreted by the adrenal glands....


Posterior pituitary
Posterior pituitary

The posterior pituitary comprises the posterior lobe of the pituitary gland and is part of the endocrine system....
 lobe (neurohypophysis)
f ing Secreted hormone Abbreviation From cells Effect
Oxytocin
Oxytocin

Oxytocin is a mammalian hormone that also acts as a neurotransmitter in the brain.It is best known for its roles in female reproduction: it is released in large amounts after distension of the cervix and vagina during labor, and after stimulation of the nipples, facilitating childbirth and breastfeeding, respectively....
Magnocellular neurosecretory cell
Magnocellular neurosecretory cell

Magnocellular neurosecretory cells are large cell s within the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are also found in smaller numbers in accessory cell groups between these two nuclei, the largest one being the nucleus circularis....
s
Contraction of cervix
Cervix

The cervix is the lower, narrow portion of the uterus where it joins with the top end of the vagina. It is cylindrical or conical in shape and protrudes through the upper anterior vaginal wall....
 and vagina
Vagina

The vagina is a fibromuscular cylinder tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles....
Involved in orgasm
Orgasm

An orgasm is the conclusion of the Human sexual response cycle#Plateau phase of Human sexual response cycle, and may be experienced by both males and females....
, trust between people. and circadian homeostasis (body temperature, activity level, wakefulness). release breast milk
Vasopressin
Vasopressin

Arginine vasopressin , also known as vasopressin, argipressin or antidiuretic hormone , is a hormone found in most mammals, including humans....
 or antidiuretic hormone
AVP or ADH Magnocellular neurosecretory cell
Magnocellular neurosecretory cell

Magnocellular neurosecretory cells are large cell s within the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are also found in smaller numbers in accessory cell groups between these two nuclei, the largest one being the nucleus circularis....
s
retention of water in kidney
Kidney

The kidneys are Organ that have numerous biological roles. Their primary role is to maintain the homeostasis balance of bodily fluids by filtering and secreting Metabolomics#Metabolitess and minerals from the blood and excreting them, along with water , as urine....
s moderate vasoconstriction
Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, particularly the large arteries, arterioles and veins....


Oxytocin and anti-diuretic hormone are not secreted in the posterior lobe, merely stored.

Intermediate pituitary
Pars intermedia

Pars intermedia is the boundary between the anterior and posterior lobes of the pituitary. It contains three types of cells - Anterior pituitary basophils, chromophobes, and colloid-filled cysts....
 lobe (pars intermedia)
Secreted hormone Abbreviation From cells Effect
Melanocyte-stimulating hormone
Melanocyte-stimulating hormone

The melanocyte-stimulating hormones are a class of peptide hormones that in nature are produced by cells in the intermediate lobe of the pituitary gland....
MSH Melanotroph
Melanotroph

A Melanotroph is a cell in the pituitary gland which generates melanocyte-stimulating hormone from its precursor Proopiomelanocortin....
 
melanogenesis by melanocyte
Melanocyte

Melanocytes are cell located in the bottom layer of the skin's epidermis , the middle layer of the eye , the inner ear, meninges, bones and heart....
s in skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
 and hair
Hair

Hair is a protein filament that epidermal growth from hair follicle deep within the dermis. The fine, soft hair found on many nonhuman mammals is typically called fur; wool is the characteristically curly hair found on sheep and goats....
.


Thyroid
Thyroid

The thyroid is one of the largest endocrine glands in the body. This gland is found in the neck inferior to the thyroid cartilage and at approximately the same level as the cricoid cartilage....

Secreted hormone Abbreviation From cells Effect
Triiodothyronine
Triiodothyronine

Triiodothyronine, carbonhydrogeniodinenitrogenoxygen, also known as T3, is a thyroid hormone.Thyroid-stimulating hormone activates the production of thyroxine and T3....
T3 Thyroid epithelial cell
Thyroid epithelial cell

Thyroid epithelial cells are cells in the thyroid gland that produce and secrete thyroxine and triiodothyronine .The main function of the thyroid gland is to take iodine, found in many foods, and convert it into thyroid hormones: thyroxine and triiodothyronine .Thyroid cells are the only cells in the body which can absorb iodine....
 
potent form of thyroid hormone
Thyroid hormone

The thyroid hormones, thyroxine and triiodothyronine , are tyrosine-based hormones produced by the thyroid gland. An important component in the synthesis of thyroid hormones is iodine....
: increase the basal metabolic rate
Basal metabolic rate

Basal metabolic rate is the amount of energy expended while at rest in a neutrally temperate environment, in the post-absorptive state . The release of energy in this state is sufficient only for the functioning of the vital organs, such as the heart, lungs, brain and the rest of the nervous system, liver, kidneys, sex organs, muscles and sk...
 & sensitivity to catecholamine
Catecholamine

Catecholamines are chemical compounds derived from the amino acid tyrosine. Their name is derived from the fact that they contain catechol and amine moieties....
s, affect protein synthesis
Protein synthesis

Protein synthesis is the creation of proteins using DNA and RNA. Proteins can often be synthesized directly from genes by Translation mRNA. When a protein is harmful and needs to be available on short notice or in large quantities, a protein precursor is produced....
Thyroxine
Thyroxine

Thyroxine, or 3,5,3',5'-tetra?iodothyronine , a form of thyroid hormones is the major hormone secreted by the follicular cells of the thyroid gland....
 or tetraiodothyronine
T4 Thyroid epithelial cell
Thyroid epithelial cell

Thyroid epithelial cells are cells in the thyroid gland that produce and secrete thyroxine and triiodothyronine .The main function of the thyroid gland is to take iodine, found in many foods, and convert it into thyroid hormones: thyroxine and triiodothyronine .Thyroid cells are the only cells in the body which can absorb iodine....
s
less active form of thyroid hormone
Thyroid hormone

The thyroid hormones, thyroxine and triiodothyronine , are tyrosine-based hormones produced by the thyroid gland. An important component in the synthesis of thyroid hormones is iodine....
: increase the basal metabolic rate
Basal metabolic rate

Basal metabolic rate is the amount of energy expended while at rest in a neutrally temperate environment, in the post-absorptive state . The release of energy in this state is sufficient only for the functioning of the vital organs, such as the heart, lungs, brain and the rest of the nervous system, liver, kidneys, sex organs, muscles and sk...
 & sensitivity to catecholamine
Catecholamine

Catecholamines are chemical compounds derived from the amino acid tyrosine. Their name is derived from the fact that they contain catechol and amine moieties....
s, affect protein synthesis
Protein synthesis

Protein synthesis is the creation of proteins using DNA and RNA. Proteins can often be synthesized directly from genes by Translation mRNA. When a protein is harmful and needs to be available on short notice or in large quantities, a protein precursor is produced....
, often functions as a prohormone
Prohormone

A prohormone is a substance that is a precursor to a hormone, usually having minimal hormonal effect by itself. The term has been used in medical science since the middle of the 20th century....
Calcitonin
Calcitonin

Calcitonin is a 32-amino acid linear polypeptide hormone that is producedin humans primarily by the Parafollicular cell cells of the thyroid, and in many other animals in the ultimobranchial body....
Parafollicular cell
Parafollicular cell

Parafollicular cells are cells in the thyroid which produce and secrete calcitonin. They are located adjacent to the thyroid follicles and reside in the connective tissue....
s
Construct bone reduce blood Ca2+
Calcium

Calcium is the chemical element with the symbol Ca and atomic number 20. It has an atomic mass of 40.078 amu. Calcium is a soft grey alkaline earth metal, and is the fifth most abundant element by mass in the earth's Crust ....


Parathyroid

Secreted hormone Abbreviation From cells Effect
Parathyroid hormone
Parathyroid hormone

Parathyroid hormone , or parathormone, is secreted by the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium in the blood, whereas calcitonin acts to decrease calcium concentration....
PTH Parathyroid chief cell
Parathyroid chief cell

Parathyroid chief cells are cell in the parathyroid glands which produce parathyroid hormone.The end result of increased secretion by the chief cells of a parathyroid gland is an increase in the blood plasma level of Calcium....
 
increase blood Ca2+
Calcium

Calcium is the chemical element with the symbol Ca and atomic number 20. It has an atomic mass of 40.078 amu. Calcium is a soft grey alkaline earth metal, and is the fifth most abundant element by mass in the earth's Crust ....
: *indirectly stimulate osteoclast
Osteoclast

An osteoclast is a type of bone cell that removes bone tissue by removing its mineralized matrix. This process is known as bone resorption....
s
  • Ca2+ reabsorption in kidney
    Kidney

    The kidneys are Organ that have numerous biological roles. Their primary role is to maintain the homeostasis balance of bodily fluids by filtering and secreting Metabolomics#Metabolitess and minerals from the blood and excreting them, along with water , as urine....
  • activate vitamin D
    Vitamin D

    Vitamin D is a group of fat-soluble prohormones, the two major forms of which are vitamin D2 and vitamin D3 . The term vitamin D also refers to metabolites and other analogues of these substances....
(Slightly) decrease blood phosphate
Phosphate

A phosphate, an inorganic chemical, is a Salt of phosphoric acid. Inorganic phosphates are mining to obtain phosphorus for use in agriculture and industry....
:
  • decreased reuptake in kidney
    Kidney

    The kidneys are Organ that have numerous biological roles. Their primary role is to maintain the homeostasis balance of bodily fluids by filtering and secreting Metabolomics#Metabolitess and minerals from the blood and excreting them, along with water , as urine....
     but increased uptake from bones
  • activate vitamin D
    Vitamin D

    Vitamin D is a group of fat-soluble prohormones, the two major forms of which are vitamin D2 and vitamin D3 . The term vitamin D also refers to metabolites and other analogues of these substances....


Heart
Heart

The heart is a muscle organ in all vertebrates responsible for pumping blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in annelids, mollusks, and arthropods....

Secreted hormone Abbreviation From cells Effect
Atrial-natriuretic peptide ANP Cardiac myocytes
Cardiac muscle

Cardiac muscle is a type of involuntary sarcomere muscle found in the walls of the heart, specifically the wikt:myocardium. Cardiac muscle cells are known as cardiac myocytes ....
 
Reduce blood pressure
Blood pressure

Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels, and constitutes one of the principal vital signs. The pressure of the circulating blood decreases as it moves away from the heart through artery and capillary, and toward the heart through veins....
 by: reducing systemic
Systemic circulation

Systemic circulation is the portion of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart....
 vascular resistance
Vascular resistance

Vascular resistance is a term used to define the resistance to flow that must be overcome to push blood through the circulatory system. The resistance offered by the peripheral circulation is known as the systemic vascular resistance , while the resistance offered by the vasculature of the lungs is known as the pulmonary vascular re...
, reducing blood water, sodium and fats
Brain natriuretic peptide
Brain natriuretic peptide

Brain natriuretic peptide , now known as B-type natriuretic peptide or GC-B, is a 32 amino acid polypeptide secreted by the Ventricle of the heart in response to excessive stretching of heart muscle cells ....
BNP Cardiac myocytes
Cardiac muscle

Cardiac muscle is a type of involuntary sarcomere muscle found in the walls of the heart, specifically the wikt:myocardium. Cardiac muscle cells are known as cardiac myocytes ....
 
(To a lesser degree than ANP) reduce blood pressure
Blood pressure

Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels, and constitutes one of the principal vital signs. The pressure of the circulating blood decreases as it moves away from the heart through artery and capillary, and toward the heart through veins....
 by: reducing systemic
Systemic circulation

Systemic circulation is the portion of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart....
 vascular resistance
Vascular resistance

Vascular resistance is a term used to define the resistance to flow that must be overcome to push blood through the circulatory system. The resistance offered by the peripheral circulation is known as the systemic vascular resistance , while the resistance offered by the vasculature of the lungs is known as the pulmonary vascular re...
, reducing blood water, sodium and fats


Striated muscle
Striated muscle

Striated muscle is a form of fibres that are combined into parallel fibres. More specifically, it can refer to:* Skeletal muscle* Cardiac muscle~cardiac referring to the heart....

Secreted hormone From cells Effect
Thrombopoietin
Thrombopoietin

Thrombopoietin , also known as THPO, is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow....
Myocyte
Myocyte

A myocyte is the type of Cell found in muscles. They arise from myoblasts.Each myocyte contains myofibrils, which are long chains of sarcomeres, the contractile units of the cell....
s
stimulates megakaryocyte
Megakaryocyte

The megakaryocyte is a bone marrow cell responsible for the production of blood thrombocytes , which are necessary for normal blood clotting....
s to produce platelets


Skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....

Secreted hormone From cells Effect
Calcidiol
Calcidiol

Calcifediol , also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D , is a prehormone which is produced by hydroxylation of vitamin D3 in the liver....
 (25-hydroxyvitamin D3)
Inactive form of Vitamin D3


Adipose tissue
Adipose tissue

In histology, adipose tissue or fat is loose connective tissue composed of adipocytes. Adipose tissue is derived from lipoblasts. Its main role is to store energy in the form of fat, although it also cushions and Thermal insulation the body....

Secreted hormone From cells Effect
Leptin
Leptin

Leptin is a 16 Atomic mass unit protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism....
 (Primarily)
Adipocyte
Adipocyte

Adipocytes are the cell s that primarily compose adipose tissue, specialized in storing energy as fat.There are two types of adipose tissue, white adipose tissue and brown adipose tissue , which are also known as white fat and brown fat, respectively, and comprise two types of fat cells....
s
decrease of appetite
Appetite

The appetite is the desire to eating food, felt as hunger. Appetite exists in all higher lifeforms, and serves to regulate adequate energy intake to maintain metabolism needs....
 and increase of metabolism
Metabolism

Metabolism is the set of chemical reactions that occur in living organisms in order to maintain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments....
.
Estrogen
Estrogen

Estrogens are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone....
s (mainly Estrone
Estrone

Estrone is an estrogenic hormone secreted by the ovary as well as adipose.Estrone is one of the three estrogens, which also include estriol and estradiol....
)
Adipocyte
Adipocyte

Adipocytes are the cell s that primarily compose adipose tissue, specialized in storing energy as fat.There are two types of adipose tissue, white adipose tissue and brown adipose tissue , which are also known as white fat and brown fat, respectively, and comprise two types of fat cells....
s
 


Stomach
Stomach

In most mammals, the stomach is a hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication....

Secreted hormone Abbreviation From cells Effect
Gastrin
Gastrin

In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the stomach, duodenum, and the pancreas....
 (Primarily)
G cell
G cell

In anatomy, the G cell is a type of cell in the stomach that secretes gastrin. It works in conjunction with gastric chief cells and parietal cells....
s
Secretion of gastric acid
Gastric acid

Gastric acid is one of the main secretions of the stomach, together with several enzymes and intrinsic factor. Chemically it is an acid solution with a pH of 1 to 2 in the stomach lumen , consisting mainly of hydrochloric acid , and large quantities of potassium chloride and sodium chloride ....
 by parietal cell
Parietal cell

Parietal cells, or oxyntic cells, are the stomach epithelium cell s that secrete gastric acid and intrinsic factor....
s
Ghrelin
Ghrelin

Ghrelin is a hormone produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas that stimulates appetite....
P/D1 cell
P/D1 cell

Cell lining the Fundus of the human stomach that produce ghrelin. Removal of these cells in gastric bypass surgery has a profound impact on later appetite regulation....
s
Stimulate appetite
Appetite

The appetite is the desire to eating food, felt as hunger. Appetite exists in all higher lifeforms, and serves to regulate adequate energy intake to maintain metabolism needs....
, secretion of growth hormone
Growth hormone

Growth hormone is a peptide hormone. It stimulates human development and cell reproduction in humans and other animals. It is a 191-amino acid, single chain polypeptide hormone which is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland....
 from anterior pituitary gland
Neuropeptide Y
Neuropeptide Y

Neuropeptide Y is a 36 amino acid peptide neurotransmitter found in the brain and autonomic nervous system.NPY has been associated with a number of physiologic processes in the brain, including the regulation of energy balance, memory and learning, and epilepsy....
NPY increased food intake and decreased physical activity
Secretin
Secretin

Secretin is a peptide hormone produced in the S cells of the duodenum in the crypts of Lieberk?hn. Its primary effect is to regulate the pH of the duodenal contents via the control of gastric acid secretion and buffering with bicarbonate....
S cell
S cell

S cells are cells which release secretin, found in the jejunum and duodenum. They are stimulated by a drop in pH to 4 or below in the small intestine's lumen....
s
Secretion of bicarbonate
Bicarbonate

In inorganic chemistry, bicarbonate is an intermediate form in the deprotonation of carbonic acid. Its chemical formula is HCO3−....
 from liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....
, pancreas
Pancreas

The pancreas is a gland Organ in the digestive system and endocrine system of vertebrates. It is both an endocrine gland , as well as an exocrine gland, secreting pancreatic juice containing Digestion enzymes that pass to the small intestine....
 and duodenal Brunner's glands Enhances effects of cholecystokinin
Cholecystokinin

Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesised by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of the small intestine, and ca...
Stops production of gastric juice
Somatostatin
Somatostatin

Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones....
D cell
D cell

D cell can mean:* D battery, a common size of Battery * D cell , a hormone secreting, regulatory cell type found in the stomach...
s
Suppress release of gastrin
Gastrin

In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the stomach, duodenum, and the pancreas....
, cholecystokinin
Cholecystokinin

Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesised by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of the small intestine, and ca...
 (CCK), secretin
Secretin

Secretin is a peptide hormone produced in the S cells of the duodenum in the crypts of Lieberk?hn. Its primary effect is to regulate the pH of the duodenal contents via the control of gastric acid secretion and buffering with bicarbonate....
, motilin
Motilin

Motilin is a 22 amino acid polypeptide hormone which in humans is encoded by the MLN gene.Motilin secreted by M cells that are numerous in crypts of the small intestine, especially in the duodenum and jejunum....
, vasoactive intestinal peptide
Vasoactive intestinal peptide

Vasoactive intestinal peptide is a peptide hormone containing 28 amino acid residue s and is produced in many areas of the human body including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain....
 (VIP), gastric inhibitory polypeptide (GIP), enteroglucagon
Enteroglucagon

Enteroglucagon is a peptide hormone derived from preproglucagon. It is a gastrointestinal hormone, secreted from mucosal cells primarily of the Colon and terminal ileum....
Lowers rate of gastric emptying Reduces smooth muscle
Smooth muscle

Smooth muscle is a type of non-striated muscle, found within the tunica media layer of large and small arteries and veins, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, the ciliary muscle, and iris of the eye....
 contractions and blood flow within the intestine.
Histamine
Histamine

Histamine is a biogenic amine involved in local immune system as well as regulating physiological function in the gut and acting as a neurotransmitter....
ECL cells stimulate gastric acid
Gastric acid

Gastric acid is one of the main secretions of the stomach, together with several enzymes and intrinsic factor. Chemically it is an acid solution with a pH of 1 to 2 in the stomach lumen , consisting mainly of hydrochloric acid , and large quantities of potassium chloride and sodium chloride ....
 secretion
Endothelin
Endothelin

Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure and heart disease....
X cells Smooth muscle
Smooth muscle

Smooth muscle is a type of non-striated muscle, found within the tunica media layer of large and small arteries and veins, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, the ciliary muscle, and iris of the eye....
 contraction of stomach


Duodenum
Duodenum

The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms anterior intestine or proximal intestine may be used instead of duodenum....

Secreted hormone From cells Effect
Cholecystokinin
Cholecystokinin

Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesised by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of the small intestine, and ca...
I cells Release of digestive enzyme
Enzyme

Enzymes are biomolecules that catalysis chemical reactions. Almost all enzymes are proteins. In enzymatic reactions, the molecules at the beginning of the process are called Substrate , and the enzyme converts them into different molecules, the products....
s from pancreas
Pancreas

The pancreas is a gland Organ in the digestive system and endocrine system of vertebrates. It is both an endocrine gland , as well as an exocrine gland, secreting pancreatic juice containing Digestion enzymes that pass to the small intestine....
Release of bile
Bile

Bile or gall is a bitter yellow or green fluid secreted by hepatocytes from the liver of most vertebrates. In many species, bile is stored in the gallbladder between meals and upon eating is discharged into the duodenum where the bile aids the process of digestion of lipids....
 from gallbladder
Gallbladder

The gallbladder is a small non-vital Organ which aids in the digestive process and concentrates bile produced in the liver....
hunger
Hunger

Hunger is a feeling experienced when one has a desire to eat. The often unpleasant feeling originates in the hypothalamus and is released through receptors in the liver....
 suppressant


Liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....

Secreted hormone Abbreviation From cells Effect
Insulin-like growth factor
Insulin-like growth factor

The insulin-like growth factors are polypeptides with high Homology to insulin. IGFs are part of a complex system that cells use to communicate with their physiology environment....
 (or somatomedin) (Primarily)
IGF Hepatocyte
Hepatocyte

Hepatocytes make up 70-80% of the cytoplasmic mass of the liver.These cells are involved in protein synthesis, protein storage and transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification and excretion of exogenous and endogenous substances....
s
insulin-like effects regulate cell growth
Cell growth

The term cell growth is used in the contexts of Cell development and cell division . When used in the context of cell division, it refers to growth of cell populations, where one cell grows and divides to produce two "daughter cells"....
 and development
Angiotensinogen and angiotensin
Angiotensin

Angiotensin causes blood vessels to constrict, and drives blood pressure up. It is part of the renin-angiotensin-aldosterone system, which is a major target for drugs that lower blood pressure....
Hepatocyte
Hepatocyte

Hepatocytes make up 70-80% of the cytoplasmic mass of the liver.These cells are involved in protein synthesis, protein storage and transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification and excretion of exogenous and endogenous substances....
s
vasoconstriction
Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, particularly the large arteries, arterioles and veins....
release of aldosterone
Aldosterone

Aldosterone is a hormone that increases the reabsorption of sodium and water and the release of potassium in the kidneys. This increases the volume of fluid in the body, and drives blood pressure up....
 from adrenal cortex
Adrenal cortex

Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively....
dipsogen
Dipsogen

A dipsogen is an agent that causes thirst. ...
.
Thrombopoietin
Thrombopoietin

Thrombopoietin , also known as THPO, is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow....
Hepatocyte
Hepatocyte

Hepatocytes make up 70-80% of the cytoplasmic mass of the liver.These cells are involved in protein synthesis, protein storage and transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification and excretion of exogenous and endogenous substances....
s
stimulates megakaryocyte
Megakaryocyte

The megakaryocyte is a bone marrow cell responsible for the production of blood thrombocytes , which are necessary for normal blood clotting....
s to produce platelets


Pancreas
Pancreas

The pancreas is a gland Organ in the digestive system and endocrine system of vertebrates. It is both an endocrine gland , as well as an exocrine gland, secreting pancreatic juice containing Digestion enzymes that pass to the small intestine....

Secreted hormone From cells Effect
Insulin
Insulin

Insulin is a hormone with extensive effects on both metabolism and several other body systems . Insulin causes most of the body's cells to take up glucose from the blood , storing it as glycogen in the liver and muscle, and stops use of fat as an energy source....
 (Primarily)
ß Islet cells
Beta cell

Beta cells are a type of cell in the pancreas in areas called the islets of Langerhans. They make up 65-80% of the cells in the islets....
 
Intake of glucose
Glucose

Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
, glycogenesis
Glycogenesis

Glycogenesis is the process of glycogen synthesis, in which glucose molecules are added to chains of glycogen. This process is activated by insulin in response to high glucose levels, for example after a carbohydrate containing meal....
 and glycolysis
Glycolysis

Glycolysis is the metabolic pathway that converts glucose, C6H12O6, into pyruvate, C3H5O3-....
 in liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....
 and muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
 from blood intake of lipid
Lipid

Lipids are broadly defined as any fat-soluble , naturally-occurring molecule, such as fats, oils, waxes, cholesterol, sterols, fat-soluble vitamins , monoglycerides, diglycerides, phospholipids, and others....
s and synthesis of triglyceride
Triglyceride

is a glyceride in which the glycerol is esterified with three fatty acids. It is the main constituent of vegetable oil and animal fats....
s in adipocytes Other anabolic
Anabolism

Anabolism is the set of metabolic pathways that construct molecules from smaller units. These reactions require energy. One way of categorizing metabolic processes, whether at the cell ular, organ or organism level is as 'anabolic' or as 'catabolism', which is the opposite....
 effects
Glucagon
Glucagon

Glucagon is an important hormone involved in carbohydrate metabolism. Produced by the pancreas, it is released when the glucose level in the blood is low , causing the liver to convert stored glycogen into glucose and release it into the bloodstream....
 (Also Primarily)
a Islet cells
Alpha cell

Alpha cells are endocrine system cell s in the islets of Langerhans of the pancreas. They make up 15-20% of the cells in the islets. They are responsible for synthesizing and secreting the peptide hormone glucagon, which elevates the glucose levels in the blood....
 
glycogenolysis
Glycogenolysis

Glycogenolysis is the catabolism of glycogen by removal of a glucose monomer through cleavage with inorganic phosphate to produce glucose-1-phosphate....
 and gluconeogenesis
Gluconeogenesis

Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as lactic acid, glycerol, and glucogenic amino acids....
 in liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....
increases blood glucose level
Somatostatin
Somatostatin

Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones....
d Islet cells
Delta cell

Delta cells are somatostatin producing cell s.They can be found in the stomach, intestine and the Islets of Langerhans in the pancreas.In rodents delta-cells are located in the periphery of the islets; in humans the islet architecture is generally less organized and delta-cells are frequently observed inside the islets as well....
 
Inhibit release of insulin
Insulin

Insulin is a hormone with extensive effects on both metabolism and several other body systems . Insulin causes most of the body's cells to take up glucose from the blood , storing it as glycogen in the liver and muscle, and stops use of fat as an energy source....
Inhibit release of glucagon
Glucagon

Glucagon is an important hormone involved in carbohydrate metabolism. Produced by the pancreas, it is released when the glucose level in the blood is low , causing the liver to convert stored glycogen into glucose and release it into the bloodstream....
Suppress the exocrine secretory action of pancreas
Pancreas

The pancreas is a gland Organ in the digestive system and endocrine system of vertebrates. It is both an endocrine gland , as well as an exocrine gland, secreting pancreatic juice containing Digestion enzymes that pass to the small intestine....
.
Pancreatic polypeptide
Pancreatic polypeptide

Pancreatic polypeptide is a polypeptide secreted by PP cells in the endocrine pancreas predominantly in the head of the pancreas. It consists of 36 amino acids and has molecular weight about 4200 Dalton_%28unit%29....
PP cell
PP cell

PP cells are pancreatic polypeptide producing cell in the islets of Langerhans in the pancreas. They are very few in number and are polygonal in shape....
s
Unknown


Kidney
Kidney

The kidneys are Organ that have numerous biological roles. Their primary role is to maintain the homeostasis balance of bodily fluids by filtering and secreting Metabolomics#Metabolitess and minerals from the blood and excreting them, along with water , as urine....

Secreted hormone From cells Effect
Renin
Renin

Renin , also known as Angiotensinogenase, is a circulating enzyme that participates in the body's renin-angiotensin system that mediates extracellular volume , and arterial vasoconstriction....
 (Primarily)
Juxtaglomerular cell
Juxtaglomerular cell

In the kidney, the juxtaglomerular cells are cells that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells in the wall of the nephron that delivers blood to the glomerulus ....
s
Activates the renin-angiotensin system
Renin-angiotensin system

The renin-angiotensin system or the renin-angiotensin-aldosterone system is a hormone system that regulates blood pressure and water balance....
 by producing angiotensin I of angiotensinogen
Erythropoietin
Erythropoietin

Erythropoietin, or its alternative erythropoetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production....
 (EPO)
Extraglomerular mesangial cell
Extraglomerular mesangial cell

Extraglomerular mesangial cells are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa....
s
Stimulate erythrocyte production
Calcitriol
Calcitriol

Calcitriol or 1,25-dihydroxycholecalciferol is the active form of vitamin D found in the body . It increases the absorption of calcium and phosphate from the gastrointestinal tract and kidneys and inhibits release of calcitonin....
 (1,25-dihydroxyvitamin D3)
Active form of vitamin D3 Increase absorption of calcium
Calcium

Calcium is the chemical element with the symbol Ca and atomic number 20. It has an atomic mass of 40.078 amu. Calcium is a soft grey alkaline earth metal, and is the fifth most abundant element by mass in the earth's Crust ....
 and phosphate
Phosphate

A phosphate, an inorganic chemical, is a Salt of phosphoric acid. Inorganic phosphates are mining to obtain phosphorus for use in agriculture and industry....
 from gastrointestinal tract
Gastrointestinal tract

The digestive tract is the system of Organ s within multicellular animals that takes in food, digestion it to extract energy and nutrients, and expels the remaining waste....
 and kidneys inhibit release of PTH
Parathyroid hormone

Parathyroid hormone , or parathormone, is secreted by the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium in the blood, whereas calcitonin acts to decrease calcium concentration....
Thrombopoietin
Thrombopoietin

Thrombopoietin , also known as THPO, is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow....
stimulates megakaryocyte
Megakaryocyte

The megakaryocyte is a bone marrow cell responsible for the production of blood thrombocytes , which are necessary for normal blood clotting....
s to produce platelets


Adrenal gland
Adrenal gland

In mammals, the adrenal glands are the star-shaped endocrine glands that sit on top of the kidneys; their name indicates that position . They are chiefly responsible for regulating the stress response through the biosynthesis of corticosteroids and catecholamines, including cortisol and adrenaline, respectively....
s


Adrenal cortex
Adrenal cortex

Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively....
Secreted hormone From cells Effect
Glucocorticoid
Glucocorticoid

Glucocorticoids are a class of steroid hormones which bind to the glucocorticoid receptor , which is present in almost every animal cell.GCs are part of the feedback mechanism in the immune system which turns immune activity down....
s (chiefly cortisol
Cortisol

Cortisol is a corticosteroid hormone or glucocorticoid produced by the adrenal cortex, that is part of the adrenal gland . It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by Corticotropin-releasing hormone....
)
zona fasciculata
Zona fasciculata

Cells of the zona fasciculata sit directly beneath the zona glomerulosa and are organized in bundles .The zona chiefly produces glucocorticoids and a small amount of weak androgens .Adrenal tumour of the zona fasciculata may lead to primary adrenocortical hypersecretion....
 and zona reticularis
Zona reticularis

The zona reticularis is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance ....
 cells
Stimulation of gluconeogenesis
Gluconeogenesis

Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as lactic acid, glycerol, and glucogenic amino acids....
Inhibition of glucose uptake in muscle and adipose tissue Mobilization of amino acids from extrahepatic tissues Stimulation of fat breakdown in adipose tissue anti-inflammatory
Anti-inflammatory

Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids which affect the brain....
 and immunosuppressive
Mineralocorticoid
Mineralocorticoid

Mineralocorticoids are a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt balance and water balance ....
s (chiefly aldosterone
Aldosterone

Aldosterone is a hormone that increases the reabsorption of sodium and water and the release of potassium in the kidneys. This increases the volume of fluid in the body, and drives blood pressure up....
)
Zona glomerulosa
Zona glomerulosa

The zona glomerulosa of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the adrenal gland's capsule....
 cells
Increase blood volume
Blood volume

Blood volume is the volume of blood in a person's circulatory system. A typical adult male human has a blood volume of approximately five litres ....
 by reabsorption of sodium
Sodium

Sodium is an element which has the symbol Na , atomic number 11, atomic mass 23 amu , and a common oxidation number +1. Sodium is a soft, silvery white, highly reactive element and is a member of the alkali metals within "group 1" ....
 in kidneys (primarily) Potassium
Potassium

Potassium is a chemical element. It has the symbol K , atomic number 19, and atomic mass 39.0983. Potassium was first isolated from potash, hence the name....
 and H+
Hydrogen ion

Hydrogen ion is recommended by IUPAC as a general term for all ions of hydrogen and its isotopes. Depending on the charge of the ion, two different classes can be distinguished:...
 secretion in kidney.
Androgen
Androgen

Androgen is the generic term for any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors....
s (including DHEA
Dehydroepiandrosterone

Dehydroepiandrosterone is a multi-functional steroid that has been implicated in a broad range of biological effects in humans and other mammals....
 and testosterone
Testosterone

Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testis of males and the ovaries of females, although small amounts are also secreted by the adrenal glands....
)
Zona fasciculata
Zona fasciculata

Cells of the zona fasciculata sit directly beneath the zona glomerulosa and are organized in bundles .The zona chiefly produces glucocorticoids and a small amount of weak androgens .Adrenal tumour of the zona fasciculata may lead to primary adrenocortical hypersecretion....
 and Zona reticularis
Zona reticularis

The zona reticularis is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance ....
 cells
Virilization
Virilization

In biology and medicine, virilization refers to the biological development of sex differences, changes which make a male body different from a female body....
, anabolic


Adrenal medulla
Adrenal medulla

The adrenal medulla is part of the adrenal gland. It is located at the center of the gland, being surrounded by the adrenal cortex.Basic...
Secreted hormone From cells Effect
Adrenaline (epinephrine) (Primarily)Chromaffin cell
Chromaffin cell

Chromaffin cells are neuroendocrine cells found in the adrenal medulla of the adrenal gland and in other autonomic ganglion of the sympathetic nervous system....
s
Fight-or-flight response
Fight-or-flight response

'The 'fight-or-flight response', also called the fright, fight or flight response', 'hyperarousal' or the 'acute stress response', was first described by Walter Cannon in 1915....
:
  • Boost the supply of oxygen
    Oxygen

    Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
     and glucose
    Glucose

    Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
     to the brain
    Brain

    The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
     and muscles (by increasing heart rate
    Heart rate

    Heart rate is a measure of the number of heart beats per minute . The average resting human heart rate is about 70 bpm for adult males and 75 bpm for adult females....
     and stroke volume
    Stroke volume

    In cardiovascular physiology, stroke volume is the volume of blood pumped from one ventricles of the heart of the heart with each beat. It is calculated by subtracting the volume of blood in the ventricle at the end of a beat from the volume of blood just prior to the beat ....
    , vasodilation
    Vasodilation

    Vasodilation refers to the widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls, particularly in the large arteries, smaller arterioles and large veins....
    , increasing catalysis
    Catalysis

    Catalysis is the process in which the reaction rate of a chemical reaction is either increased or decreased by means of a chemical substance known as a catalyst....
     of glycogen
    Glycogen

    Glycogen is a polysaccharide of glucose which functions as the secondary short term energy storage in animal cells. It is made primarily by the liver and the muscles, but can also be made by the brain and stomach....
     in liver, breakdown of lipid
    Lipid

    Lipids are broadly defined as any fat-soluble , naturally-occurring molecule, such as fats, oils, waxes, cholesterol, sterols, fat-soluble vitamins , monoglycerides, diglycerides, phospholipids, and others....
    s in fat cells
    Adipocyte

    Adipocytes are the cell s that primarily compose adipose tissue, specialized in storing energy as fat.There are two types of adipose tissue, white adipose tissue and brown adipose tissue , which are also known as white fat and brown fat, respectively, and comprise two types of fat cells....
    )
  • Dilate the pupil
    Pupil

    The pupil is the sphere that is located in the center of the Iris of the eye and that controls the amount of light that enters the eye. It appears black because most of the light entering the pupil is absorbed by the biological tissue inside the eye....
    s
  • Suppress non-emergency bodily processes (e.g., digestion
    Digestion

    Digestion is the mechanical and chemical breaking down of food into smaller components, to a form that can be Absorption, for instance, by a blood stream....
    )
  • Suppress immune system
    Immune system

    An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells....
Noradrenaline (norepinephrine) Chromaffin cell
Chromaffin cell

Chromaffin cells are neuroendocrine cells found in the adrenal medulla of the adrenal gland and in other autonomic ganglion of the sympathetic nervous system....
s
Fight-or-flight response
Fight-or-flight response

'The 'fight-or-flight response', also called the fright, fight or flight response', 'hyperarousal' or the 'acute stress response', was first described by Walter Cannon in 1915....
:
  • Boost the supply of oxygen
    Oxygen

    Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
     and glucose
    Glucose

    Glucose , a monosaccharide also known as grape sugar, blood sugar, or corn sugar, is a very important carbohydrate in biology....
     to the brain
    Brain

    The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
     and muscles (by increasing heart rate
    Heart rate

    Heart rate is a measure of the number of heart beats per minute . The average resting human heart rate is about 70 bpm for adult males and 75 bpm for adult females....
     and stroke volume
    Stroke volume

    In cardiovascular physiology, stroke volume is the volume of blood pumped from one ventricles of the heart of the heart with each beat. It is calculated by subtracting the volume of blood in the ventricle at the end of a beat from the volume of blood just prior to the beat ....
    , vasoconstriction
    Vasoconstriction

    Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, particularly the large arteries, arterioles and veins....
     and increased blood pressure
    Blood pressure

    Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels, and constitutes one of the principal vital signs. The pressure of the circulating blood decreases as it moves away from the heart through artery and capillary, and toward the heart through veins....
    , breakdown of lipid
    Lipid

    Lipids are broadly defined as any fat-soluble , naturally-occurring molecule, such as fats, oils, waxes, cholesterol, sterols, fat-soluble vitamins , monoglycerides, diglycerides, phospholipids, and others....
    s in fat cells
    Adipocyte

    Adipocytes are the cell s that primarily compose adipose tissue, specialized in storing energy as fat.There are two types of adipose tissue, white adipose tissue and brown adipose tissue , which are also known as white fat and brown fat, respectively, and comprise two types of fat cells....
    )
  • Increase skeletal muscle
    Skeletal muscle

    They generally contract voluntarily , although they can contract involuntarily through Reflex action. The whole muscle is wrapped in a special type of connective tissue, epimysium....
     readiness.
  • Dopamine
    Dopamine

    Dopamine is a neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the human brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors ? D1, D2, D3, D4 and D5, and their variants....
    Chromaffin cell
    Chromaffin cell

    Chromaffin cells are neuroendocrine cells found in the adrenal medulla of the adrenal gland and in other autonomic ganglion of the sympathetic nervous system....
    s
    Increase heart
    Heart

    The heart is a muscle organ in all vertebrates responsible for pumping blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in annelids, mollusks, and arthropods....
     rate and blood pressure
    Blood pressure

    Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels, and constitutes one of the principal vital signs. The pressure of the circulating blood decreases as it moves away from the heart through artery and capillary, and toward the heart through veins....
    Enkephalin
    Enkephalin

    An enkephalin is a pentapeptide involved in regulating pain and nociception in the body. The enkephalins are termed endogenous ligands, or specifically endorphins, as they are internally derived and bind to the body's opioid receptors....
    Chromaffin cell
    Chromaffin cell

    Chromaffin cells are neuroendocrine cells found in the adrenal medulla of the adrenal gland and in other autonomic ganglion of the sympathetic nervous system....
    s
    Regulate pain


    Testes
    Secreted hormone From cells Effect
    Androgen
    Androgen

    Androgen is the generic term for any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors....
    s (chiefly testosterone
    Testosterone

    Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testis of males and the ovaries of females, although small amounts are also secreted by the adrenal glands....
    )
    Leydig cell
    Leydig cell

    Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testes. They can secrete testosterone and are often closely related to nerves....
    s
    Anabolic: growth of muscle mass and strength, increased bone density
    Bone density

    Bone density is a medical term referring to the amount of matter per cubic centimeter of bones. It is measured by a procedure called densitometry, often performed in the radiology or nuclear medicine departments of hospitals or clinics....
    , growth and strength, Virilizing: maturation
    Maturation

    Maturation could refer to any of the following:* Fetal development* Developmental biology* Erikson's stages of psychosocial development* Or physical maturation of any biological life form - see individual articles for maturation of different life forms....
     of sex organs, formation of scrotum
    Scrotum

    In some male mammals the scrotum is a protuberance of skin and muscle containing the testicles. It is an extension of the abdomen, and is located between the penis and anus....
    , deepening of voice, growth of beard
    Beard

    A beard is the hair that grows on a person's chin, cheeks, neck, and the area above the upper lip. Typically, only males going through puberty, or post-pubescent males are able to grow beards....
     and axillary hair.
    Estradiol
    Estradiol

    Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including bone structure....
    Sertoli cell
    Sertoli cell

    A Sertoli cell is a 'nurse' cell of the testicle which is part of a seminiferous tubule.It is activated by follicle-stimulating hormone, and has FSH-receptor on its membranes....
    s
    Prevent apoptosis
    Apoptosis

    Apoptosis is the process of programmed cell death that may occur in multicellular organisms. Programmed Cell death involves a series of biochemical events leading to a characteristic cell Morphology and death, in more specific terms, a series of biochemical events that lead to a variety of morphological changes, including Bleb , changes...
     of germ cells
    Inhibin
    Inhibin

    Inhibin is a peptide that is an Enzyme inhibitor of FSH synthesis and secretion, and participates in the regulation of the menstrual cycle....
    Sertoli cell
    Sertoli cell

    A Sertoli cell is a 'nurse' cell of the testicle which is part of a seminiferous tubule.It is activated by follicle-stimulating hormone, and has FSH-receptor on its membranes....
    s | Inhibit production of FSH


    Ovary
    Ovary

    The ovary is an ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in females are homology to testicle in males, in that they are both gonads and endocrine glands....

    These originate either from the ovarian follicle
    Ovarian follicle

    Ovarian follicle is the basic unit of female reproductive biology and is composed of roughly spherical aggregations of cell s found in the ovary....
     or the corpus luteum
    Corpus luteum

    The corpus luteum is a temporary endocrine structure in mammals, involved in production of progestogen, which is needed to maintain pregnancy....
    .
    Secreted hormone From cells Effect
    Progesterone
    Progesterone

    Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestogens, and is the major naturally occurring human progestogen....
    Granulosa cells, theca cells Support pregnancy
    Pregnancy

    Pregnancy is the carrying of one or more offspring, known as a fetus or embryo, inside the uterus of a female. In a pregnancy, there can be multiple gestations, as in the case of twins or Multiple birth....
    :
    • Convert endometrium to secretory stage
    • Make cervical mucus
      Cervix

      The cervix is the lower, narrow portion of the uterus where it joins with the top end of the vagina. It is cylindrical or conical in shape and protrudes through the upper anterior vaginal wall....
       permeable to sperm.
    • Inhibit immune
      Immune system

      An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells....
       response, e.g., towards the human embryo
    • Decrease uterine smooth muscle
      Smooth muscle

      Smooth muscle is a type of non-striated muscle, found within the tunica media layer of large and small arteries and veins, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, the ciliary muscle, and iris of the eye....
       contractility
    • Inhibit lactation
      Lactation

      Lactation describes the secretion of milk from the mammary glands, the process of providing that milk to the young, and the period of time that a mother lactates to feed her young....
    • Inhibit onset of labor.


    Other:
    • Raise epidermal growth factor-1 levels
    • Increase core temperature during ovulation
    • Reduce spasm
      Spasm

      A spasm is a sudden, involuntary contraction of a muscle, a group of muscles, or a hollow Organ , or a similarly sudden contraction of an orifice....
       and relax smooth muscle
      Smooth muscle

      Smooth muscle is a type of non-striated muscle, found within the tunica media layer of large and small arteries and veins, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, the ciliary muscle, and iris of the eye....
       (widen bronchi and regulate mucus
      Mucus

      In vertebrates, mucus is a slippery secretion produced by, and covering, mucous membranes. It is a viscous colloid containing antiseptic enzymes and immunoglobulins that serves to protect Epithelium in the respiratory,...
      )
    Anti-inflammatory
    Inflammation

    Inflammation is the complex biological response of Blood vessel tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue....
    • Reduce gall-bladder activity
    • Normalize blood
      Blood

      Blood is a specialized bodily fluid that delivers necessary substances to the body's Cell s ? such as nutrients and oxygen ? and transports waste products away from those same cells....
       clotting and vascular tone, zinc
      Zinc

      Zinc is a metallic chemical element with the symbol Zn and atomic number 30. It is a first-row transition metal of the group 12 element of the periodic table....
       and copper
      Copper

      Copper is a chemical element with the symbol Cu and atomic number 29.It is a ductile metal with very high thermal and electrical conductivity....
       levels, cell
      Cell (biology)

      The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
       oxygen
      Oxygen

      Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
       levels, and use of fat stores for energy
    • Assist in thyroid
      Thyroid

      The thyroid is one of the largest endocrine glands in the body. This gland is found in the neck inferior to the thyroid cartilage and at approximately the same level as the cricoid cartilage....
       function and bone
      Bone

      Bones are rigid organ that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red blood cell and white blood cells and store minerals....
       growth by osteoblast
      Osteoblast

      An osteoblast is a mononucleate cell that is responsible for bone formation. Osteoblasts produce osteoid, which is composed mainly of Type I collagen....
      s
    • Increase resilience
      Resilience

      Resilience is the property of a material to absorb energy when it is deformed Elasticity and then, upon unloading to have this energy recovered....
       in bone
      Bone

      Bones are rigid organ that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red blood cell and white blood cells and store minerals....
      , teeth, gum
      Gingiva

      The gingiva , or gums, consists of the mucosal tissue that lies over the alveolar bone....
      s, joint
      Joint

      A joint is the location at which two or more bones make contact. They are constructed to allow movement and provide mechanical support, and are classified structurally and functionally....
      , tendon
      Tendon

      A tendon is a tough band of fibrous connective tissue that usually connects muscle to bone and is capable of withstanding tension . Tendons are similar to ligaments except that ligaments join one bone to another....
      , ligament
      Ligament

      Ligaments connect bone to bone. In anatomy, the term ligament is used to denote three different types of structures:# Fibrous Tissue that connects bones to other bones....
      , and skin
      Skin

      The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
    • Promote healing by regulating collagen
      Collagen

      Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
    • Provide nerve function and healing by regulating myelin
      Myelin

      Myelin is an electrically-insulating dielectric material that forms a layer, the myelin sheath. Usually, myelin surrounds only the axon of a neuron....
    • Prevent endometrial cancer
      Endometrial cancer

      Endometrial cancer refers to several types of cancer which arise from the endometrium, or lining of the uterus. Endometrial cancers are the most common gynecologic cancers in the United States, with over 35,000 women diagnosed each year in the U.S....
       by regulating effects of estrogen
    Androstenedione
    Androstenedione

    Androstenedione is a 19-carbon steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemistry pathway that produces the androgen testosterone and the estrogens estrone and estradiol....
    Theca cells Substrate for estrogen
    Estrogen

    Estrogens are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone....
    Estrogens (mainly estradiol
    Estradiol

    Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including bone structure....
    )
    Granulosa cells Structural:
  • Promote formation of female secondary sex characteristics
  • Accelerate height
    Height

    Height is the measurement of vertical distance, but has two meanings in common use. It can either indicate how "tall" something is, or how "high up" it is....
     growth
  • Accelerate metabolism
    Metabolism

    Metabolism is the set of chemical reactions that occur in living organisms in order to maintain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments....
     (burn fat)
  • Reduce muscle
    MUSCLE

    MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
     mass
  • Stimulate endometrial
    Endometrium

    The endometrium is the inner membrane of the mammalian uterus....
     growth
  • Increase uterine
    Uterus

    The uterus is a major female hormone-responsive reproductive sex organ of most mammals, including humans. It is within the uterus that the fetus develops during gestation....
     growth
  • Maintain blood vessel
    Blood vessel

    The blood vessels are the part of the circulatory system that transport blood throughout the body. There are three major types of blood vessels: the artery, which carry the blood away from the heart, the capillary, which enable the actual exchange of water and chemicals between the blood and the tissues; and the veins, which carry blood from...
    s and skin
  • Reduce bone resorption
    Bone resorption

    Bone resorption is the process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood....
    , increase bone formation
  • Protein
    Protein

    Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
     synthesis:
    • Increase hepatic production of binding proteins
    Coagulation
    Coagulation

    Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis , wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop hemorrhage and begin repair of the damaged vessel....
    :
    • Increase circulating level of factors 2, 7
      Factor VII

      Factor VII is one of the central proteins in the coagulation. It is an enzyme of the serine protease class....
      , 9
      Factor IX

      Factor IX is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes Haemophilia B....
      , 10
      Factor X

      Factor X, also known by the eponym Stuart-Prower factor or as thrombokinase, is an enzyme of the coagulation. It is a serine protease ....
      , antithrombin
      Antithrombin

      Antithrombin is a small protein molecule that inactivates several enzymes of the coagulation system. It is a glycoprotein produced by the liver and consists of 432 amino acids....
       III, plasminogen
    • Increase platelet
      Platelet

      Platelets, or Thrombocyte, are small, irregularly shaped anuclear cells, 2-4?m in diameter, which are derived from fragmentation of precursor megakaryocytes....
       adhesiveness
    • Increase HDL, triglyceride
      Triglyceride

      is a glyceride in which the glycerol is esterified with three fatty acids. It is the main constituent of vegetable oil and animal fats....
      , height
      Height

      Height is the measurement of vertical distance, but has two meanings in common use. It can either indicate how "tall" something is, or how "high up" it is....
       growth
    • Decrease LDL, fat
      Fat

      Fats consist of a wide group of compounds that are generally soluble in organic solvents and largely insoluble in water. Chemistry, fats are generally ester of glycerol and fatty acids....
       deposition
    Fluid balance:
    • Regulate salt (sodium
      Sodium

      Sodium is an element which has the symbol Na , atomic number 11, atomic mass 23 amu , and a common oxidation number +1. Sodium is a soft, silvery white, highly reactive element and is a member of the alkali metals within "group 1" ....
      ) and water retention
    • Increase growth hormone
      Growth hormone

      Growth hormone is a peptide hormone. It stimulates human development and cell reproduction in humans and other animals. It is a 191-amino acid, single chain polypeptide hormone which is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland....
    • Increase cortisol
      Cortisol

      Cortisol is a corticosteroid hormone or glucocorticoid produced by the adrenal cortex, that is part of the adrenal gland . It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by Corticotropin-releasing hormone....
      , SHBG
    Gastrointestinal tract:
    • Reduce bowel motility
    • Increase cholesterol in bile
      Bile

      Bile or gall is a bitter yellow or green fluid secreted by hepatocytes from the liver of most vertebrates. In many species, bile is stored in the gallbladder between meals and upon eating is discharged into the duodenum where the bile aids the process of digestion of lipids....
    Melanin:
    • Increase pheomelanin, reduce eumelanin
    Cancer:
    • Support hormone-sensitive breast cancer
      Breast cancer

      Breast cancer is a cancer that starts in the Cell of the breast in women and men. Worldwide, breast cancer is the second most common type of cancer after lung cancer and the fifth most common cause of cancer death....
      s (Suppression of production in the body of estrogen is a treatment for these cancers.)
    Lung function:
    • Promote lung function by supporting alveoli.
    Inhibin
    Inhibin

    Inhibin is a peptide that is an Enzyme inhibitor of FSH synthesis and secretion, and participates in the regulation of the menstrual cycle....
    Granulosa cells Inhibit production of FSH from anterior pituitary
    Anterior pituitary

    The anterior pituitary comprises the Anterior#Usage in human anatomy lobe of the pituitary gland and is part of the endocrine system. Unlike the posterior pituitary, the anterior lobe is genuinely glandular, hence the root adeno in its name....


    Placenta
    Placenta

    The placenta or afterbirth is a highly vascularized ephemeral organ present in Placentalia vertebrates that connects the developing fetal tissues to the uterine wall....
     (when pregnant)

    Secreted hormone Abbreviation From cells Effect
    Progesterone
    Progesterone

    Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestogens, and is the major naturally occurring human progestogen....
     (Primarily)
    Support pregnancy
    Pregnancy

    Pregnancy is the carrying of one or more offspring, known as a fetus or embryo, inside the uterus of a female. In a pregnancy, there can be multiple gestations, as in the case of twins or Multiple birth....
    :
    • Inhibit immune
      Immune system

      An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells....
       response, towards the fetus
      Fetus

      A fetus is a developing mammal or other viviparous vertebrate, after the embryonic stage and before childbirth. The plural is fetuses, or sometimes feti....
      .
    • Decrease uterine smooth muscle
      Smooth muscle

      Smooth muscle is a type of non-striated muscle, found within the tunica media layer of large and small arteries and veins, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, the ciliary muscle, and iris of the eye....
       contractility
    • Inhibit lactation
      Lactation

      Lactation describes the secretion of milk from the mammary glands, the process of providing that milk to the young, and the period of time that a mother lactates to feed her young....
    • Inhibit onset of labor.
    • Support fetal production of adrenal mineralo- and glucosteroids.
    Other effects on mother similar to ovarian follicle-progesterone
    Estrogen
    Estrogen

    Estrogens are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone....
    s (mainly Estriol
    Estriol

    Estriol is one of the three main estrogens produced by the human body. It is only produced in significant amounts during pregnancy as it is made by the placenta....
    ) (Also Primarily)
    Effects on mother similar to ovarian follicle estrogen
    Human chorionic gonadotropin
    Human chorionic gonadotropin

    Human chorionic gonadotropin is a glycoprotein hormone produced in pregnancy that is made by the the developing embryo soon after Conception and later by the syncytiotrophoblast ....
    HCG Syncytiotrophoblast
    Syncytiotrophoblast

    Syncytiotrophoblasts are multinucleated cells found in the placenta of embryos.They are the outer syncytial layer of the trophoblasts and actively invade the uterus....
     
    promote maintenance of corpus luteum
    Corpus luteum

    The corpus luteum is a temporary endocrine structure in mammals, involved in production of progestogen, which is needed to maintain pregnancy....
     during beginning of pregnancy
    Pregnancy

    Pregnancy is the carrying of one or more offspring, known as a fetus or embryo, inside the uterus of a female. In a pregnancy, there can be multiple gestations, as in the case of twins or Multiple birth....
    Inhibit immune
    Immune system

    An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells....
     response, towards the human embryo.
    Human placental lactogen
    Human placental lactogen

    Human placental lactogen , also called human chorionic somatomammotropin, is a polypeptide placental hormone. Its structure and function is similar to that of human growth hormone....
    HPL Syncytiotrophoblast
    Syncytiotrophoblast

    Syncytiotrophoblasts are multinucleated cells found in the placenta of embryos.They are the outer syncytial layer of the trophoblasts and actively invade the uterus....
     
    increase production of insulin
    Insulin

    Insulin is a hormone with extensive effects on both metabolism and several other body systems . Insulin causes most of the body's cells to take up glucose from the blood , storing it as glycogen in the liver and muscle, and stops use of fat as an energy source....
     and IGF-1 increase insulin resistance
    Insulin resistance

    Insulin resistance is the condition in which normal amounts of insulin are inadequate to produce a normal Insulin#Physiological_effects from fat, muscle and liver cell ....
     and carbohydrate
    Carbohydrate

    Carbohydrates or saccharides are the most abundant of the four major classes of biomolecules. They fill numerous roles in living things, such as the storage and transport of energy and structural components ....
     intolerance
    Inhibin
    Inhibin

    Inhibin is a peptide that is an Enzyme inhibitor of FSH synthesis and secretion, and participates in the regulation of the menstrual cycle....
    Fetal Trophoblast
    Trophoblast

    Trophoblasts are cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta....
    s
    suppress FSH


    Uterus
    Uterus

    The uterus is a major female hormone-responsive reproductive sex organ of most mammals, including humans. It is within the uterus that the fetus develops during gestation....
     (when pregnant)

    Secreted hormone Abbreviation From cells Effect
    Prolactin
    Prolactin

    Prolactin or Luteotropic hormone is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed....
    PRL Decidual cells
    Decidual cells

    Before the fertilized ovum reaches the uterus, the mucous membrane of the body of the uterus undergoes important changes and is then known as the decidua....
     
    milk production in mammary glands
    Relaxin
    Relaxin

    Relaxin is a peptide hormone that was first described in 1926 by Frederick Hisaw.The relaxin-like peptide family belongs in the insulin superfamily and consists of 7 peptides of high structural but low sequence similarity; relaxin-1 , 2 and 3, and the insulin-like peptides, INSL3, INSL4, INSL5 and INSL6....
    Decidual cells
    Decidual cells

    Before the fertilized ovum reaches the uterus, the mucous membrane of the body of the uterus undergoes important changes and is then known as the decidua....
     
    Unclear in humans and animals


    See also

    • Releasing hormone
      Releasing hormone

      A releasing hormone or releasing factor is a hormone whose main purpose is to control the release of another hormone. The main releasing hormones secreted by the hypothalamus are:...
      s
    • Neuroendocrinology
      Neuroendocrinology

      Neuroendocrinology is the study of the interactions between the nervous system and the endocrine system. The concept arose from the recognition that the secretion of hormones from the pituitary gland is closely controlled by the brain, especially by the hypothalamus....
    • Nervous system
      Nervous system

      The nervous system is a Neural network of specialized cells that communicate information about an animal's surroundings and itself. It processes this information and causes reactions in other parts of the body....
    • Endocrine disruptor
      Endocrine disruptor

      Endocrine disruptors are exogenous substances that act like hormones in the endocrine system and disrupt the physiologic function of endogenous hormones....
    • Major systems of the human body
    • Endocrine disease
      Endocrine disease

      Among the hundreds of endocrine diseases are:* Adrenal disorders:** Adrenal insufficiency*** Addison's disease*** Congenital adrenal hyperplasia ...


    External links