EC-No
Encyclopedia
The European Commission number, or EC number, also known as EC-No and EC#, is the seven-digit code that is assigned to chemical substances that are commercially available within the European Union
European Union
The European Union is an economic and political union of 27 independent member states which are located primarily in Europe. The EU traces its origins from the European Coal and Steel Community and the European Economic Community , formed by six countries in 1958...

 . This number is assigned by the Commission of the European Union; the EC number is the official number of a substance in the European Union.

The list of substances having an EC number is called the EC Inventory. The EC Inventory includes the substances in the following inventories.
  • European Inventory of Existing Commercial Chemical Substances, EINECS
These are substances, excluding polymers, that were commercially available in the EU from 1 January 1971 to 18 September 1981. These were considered registered registered under Article 8(1) of directive 67/548/EEC
Directive 67/548/EEC
The Dangerous Substances Directive is one of the main European Union laws concerning chemical safety. It was made under Article 100 of the Treaty of Rome...

The identifying number of these substances is called the EINECS number.
  • European List of Notified Chemical Substances, ELINCS
These are substances that became commercially available after 18 September 1981 .
The identifying number of these substances is called the ELINCS number.
  • The "No-longer Polymers" list, NLP-list
The definition of polymers was changed in April, 1992 with the result that substances previously considered to be polymers were no longer excluded from regulation. Consequently, a list, called the NLP-list, was made of such substances that were commercially available between after 18 September 1981 and 31 October 1993.
The identifying number of these substances is called the NLP number.


After the pre-registration phase of REACH, ECHA has additionally assigned list numbers in the 6xx-xxx-x series to substances pre-registered with a CAS number. The 9xx-xxx-x series has been allocated to pre-registered reaction masses of more than one substance or which were pre-registered with only a chemical name as an identifier. The list of pre-registered substances is opnline.ECHA

For a substance in one of these lists, its identifying number, which will be either an EINECS number, an ELINCS number, or an NLP number, is also its EC number. The format of the identifying numbers in all three lists is the same; also, the numbers in these lists do not overlap.

The EC number is made up of seven digits according to the pattern xxx-xxx-x.
  • EINECS numbers start with number 200-001-8 (formaldehyde). There are currently 100,204 entries.
  • ELINCS numbers start with 400-010-9 (trade name: "indosol yellow SF-2RL"). There are currently 4,381 entries.
  • NLP numbers start with 500-001-0 ("2-methylpropene, trimers"). There are currently 703 entries.

The EC Number may be written in a general form as: NNN-NNN-R, where R is a check digit and N represents integers. The check digit is calculated using the ISBN method. According to this method, the check digit is the remainder
Remainder
In arithmetic, the remainder is the amount "left over" after the division of two integers which cannot be expressed with an integer quotient....

 of the following sum after division by 11:


If the remainder R is equal to 10, that combination of digits is not used for an EC number.

To illustrate, the EC number of dexamethasone
Dexamethasone
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant...

 is 200-003-9. N1 is 2, N2 through N5 are 0, and N6 is 3.


The remainder is 9, which is the check digit.

The substance to which an EC number refers (and vice versa) can be looked up on the official "European Chemical Substances Information System" web site, ESIS.

See also

  • REACH The European Union's "Registration, Evaluation, Authorisation and Restriction of Chemicals" program
  • European chemical Substances Information System
    European chemical Substances Information System
    The European chemical Substances Information System is the information system on chemicals of the European Union created by the former European Chemicals Bureau, which completed its mandate in 2008...

  • CAS registry number
    CAS registry number
    CAS Registry Numbersare unique numerical identifiers assigned by the "Chemical Abstracts Service" toevery chemical described in the...


External links

  • ESIS European Chemical Substances Information System, where EC numbers can be looked up.
  • EINECS numbers list from Chemsynthesis
  • Ovid Summary of legislation related to EC numbers
The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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