Doramectin
Encyclopedia
Doramectin is a veterinary drug approved by the Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...

 (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworm
Lungworm
Lungworms are parasitic nematode worms of the order Strongylida that infest the lungs of vertebrates. The name is used for a variety of different groups of nematodes, some of which also have other common names; what they have in common is that they migrate to their hosts' lungs or respiratory...

s, eyeworms, grubs, sucking lice and mange mites in cattle.

It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Its spectrum includes: Haemonchus spp., Ostertagia spp., Trichostrongylus
Trichostrongylus
Trichostrongylus species are nematodes , which are ubiquitous among herbivores worldwide, including cattle, sheep, donkeys, goats, deer, and rabbits ....

 spp., Cooperia
Cooperia
Cooperia is a genus of tender herbaceous perennials native to South America and the southern reaches of North America. They are closely related to Zephyranthes and Habranthus, all members of the Amaryllidaceae, or Amaryllis family. All three genera are commonly known as rain lilies because of...

 spp., Oesophagostomum
Oesophagostomum
Oesophagostomum species are free-living nematodes of the family Strongyloidae. These worms occur in Africa, Brazil, China, Indonesia and the Philippines. The majority of human infection with Oesophagostomum is localized to northern Togo and Ghana...

 spp., Dyctiocaulus viviparus, Dermatobia hominis, Boophilus microplus, Psoroptes bovis, among many other internal and external parasites.
It is available in 2 dosage forms: as an injection
Injection (medicine)
An injection is an infusion method of putting fluid into the body, usually with a hollow needle and a syringe which is pierced through the skin to a sufficient depth for the material to be forced into the body...

 and as a 5 mg/ml topical
Topical
In medicine, a topical medication is applied to body surfaces such as the skin or mucous membranes such as the vagina, anus, throat, eyes and ears.Many topical medications are epicutaneous, meaning that they are applied directly to the skin...

 solution.

Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufactured by Agrovet Market Animal Health
Agrovet Market Animal Health
Agrovet Market Animal Health is an international pharmaceutical company with corporate headquarters, in Lima, Peru.Founded in Lima in 1994, Agrovet Market Animal Health is a company involved in the animal healthcare business...

) in an 1% Doramectin Long Acting Injectable Solution for cattle
Cattle
Cattle are the most common type of large domesticated ungulates. They are a prominent modern member of the subfamily Bovinae, are the most widespread species of the genus Bos, and are most commonly classified collectively as Bos primigenius...

, sheep, swine and others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation, extending its action up to 42 days.

Doramectin is also available for horse
Horse
The horse is one of two extant subspecies of Equus ferus, or the wild horse. It is a single-hooved mammal belonging to the taxonomic family Equidae. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature into the large, single-toed animal of today...

s as an oral flavored bioadhesive gel under the name Doraquest L.A. Oral Gel. It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.
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