Domine Database
Encyclopedia
DOMINE is a free and publicly available database
of known and predicted protein domain
interactions (or domain-domain interactions). It contains interactions observed in PDB
crystal structures, and those predicted by several computational approaches. DOMINE uses Pfam
HMM profiles for protein domain
definitions. The DOMINE database contains 20,513 interactions among 4,036 domains
), which includes 4,349 known interactions inferred from PDB
structure data.
Database
A database is an organized collection of data for one or more purposes, usually in digital form. The data are typically organized to model relevant aspects of reality , in a way that supports processes requiring this information...
of known and predicted protein domain
Protein domain
A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural...
interactions (or domain-domain interactions). It contains interactions observed in PDB
Protein Data Bank
The Protein Data Bank is a repository for the 3-D structural data of large biological molecules, such as proteins and nucleic acids....
crystal structures, and those predicted by several computational approaches. DOMINE uses Pfam
Pfam
Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models.- Features :For each family in Pfam one can:* Look at multiple alignments* View protein domain architectures...
HMM profiles for protein domain
Protein domain
A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural...
definitions. The DOMINE database contains 20,513 interactions among 4,036 domains
Protein domain
A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural...
), which includes 4,349 known interactions inferred from PDB
Protein Data Bank
The Protein Data Bank is a repository for the 3-D structural data of large biological molecules, such as proteins and nucleic acids....
structure data.