Dog Appeasing Pheromone
Encyclopedia
Dog Appeasing Pheromone is a chemical developed to calm dogs suffering from separation anxiety disorder
Separation anxiety disorder
Separation anxiety disorder is a psychological condition in which an individual experiences excessive anxiety regarding separation from home or from people to whom the individual has a strong emotional attachment...

, astraphobia
Astraphobia
Astraphobia, also known as astrapophobia, brontophobia, keraunophobia, or tonitrophobia, is an abnormal fear of thunder and lightning, a type of specific phobia. It is a treatable phobia that both humans and animals can develop. The term astraphobia derives from the Greek words ἀστραπή and φόβος...

 (fear of thunder and lightning), fear of fireworks, or those with excessive barking problems.

The chemical is a synthetic analogue of a hormone produced by nursing canine mothers that is seen as 'promoting calm and secure behaviour and in establishing a bond with the mother.'

Effectiveness

A randomized clinical study published in 2008 examined the effects of DAP on puppies enrolled in socialization classes. The study found that puppies receiving the hormone exhibited less anxiety and more positive interactions with other puppies than those receiving placebo
Placebo
A placebo is a simulated or otherwise medically ineffectual treatment for a disease or other medical condition intended to deceive the recipient...

s. A double-blind
Double-blind
A blind or blinded experiment is a scientific experiment where some of the people involved are prevented from knowing certain information that might lead to conscious or subconscious bias on their part, invalidating the results....

, placebo-controlled study published in 2007 analyzed its effects on newly-adopted puppies aged 6 to 10 weeks; it found that DAP treatment induced a statistically significant reduction in crying among gun dog
Gun dog
thumb|right|A group of Gun dogs as printed in Dogs of All Nations by W.E. Mason in 1915Gun dogs, also gundogs or bird dogs, are types of dogs developed to assist hunters in finding and retrieving game, usually birds. Gun dogs are divided into three primary types: Retrievers, flushing dogs, and...

s only, and did not influence soiling.
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