Desmolase
Encyclopedia
Desmolase is an enzyme that catalyzes the formation or destruction of
carbon-carbon bonds within a molecule.
This enzyme plays a significant role in
respiration and fermentation.
Desmolases are a group enzymes involved in steroidogenesis. Examples are:
carbon-carbon bonds within a molecule.
This enzyme plays a significant role in
respiration and fermentation.
Desmolases are a group enzymes involved in steroidogenesis. Examples are:
- Cholesterol side-chain cleavage enzymeCholesterol side-chain cleavage enzymeCytochrome P450, family 11, subfamily A, polypeptide 1 , often referred to as P450scc , is a mitochondrial enzyme associated with the conversion of cholesterol to pregnenolone. The gene name is CYP11A1...
, also called 20,22-desmolase; converts cholesterol to pregnenolone. - 17,20 desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17-hydroxypregnenolone, progesterone to 17-hydroxyprogesterone, and corticosterone to cortisol.