Dalrymple's sign
Encyclopedia
Dalrymple's sign is a widened palpebral (eyelid) opening, or eyelid spasm, seen in thyrotoxicosis (as seen in Graves' disease
, exophthalmic
Goitre
and other hyperthyroid conditions), causing abnormal wideness of the palpebral fissure
. As a result of the retraction of the upper eyelid, the white of the sclera
is visible at the upper margin of the cornea
in direct outward stare. It is named after British ophthalmologist, John Dalrymple
(1803–1852).
Other eye signs described within the symptomology of Graves' disease are Stellwag's sign
(rare blinking), Rosenbach's sign (tremor of the eyelids), and Jelink's sign (hyperpigmentation of the eyelid).
Dalrymple sign is lid retraction in primary gaze.
Graves' disease
Graves' disease is an autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones...
, exophthalmic
Exophthalmos
Exophthalmos is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral or unilateral . Measurement of the degree of exophthalmos is performed using an exophthalmometer...
Goitre
Goitre
A goitre or goiter , is a swelling in the thyroid gland, which can lead to a swelling of the neck or larynx...
and other hyperthyroid conditions), causing abnormal wideness of the palpebral fissure
Palpebral fissure
Palpebral fissure is the anatomic name for the separation between the upper and lower eyelids. In adults, this measures about 10mm vertically and 30mm horizontally.It can be reduced in horizontal size by fetal alcohol syndrome and in Williams Syndrome...
. As a result of the retraction of the upper eyelid, the white of the sclera
Sclera
The sclera , also known as the white or white of the eye, is the opaque , fibrous, protective, outer layer of the eye containing collagen and elastic fiber. In the development of the embryo, the sclera is derived from the neural crest...
is visible at the upper margin of the cornea
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...
in direct outward stare. It is named after British ophthalmologist, John Dalrymple
John Dalrymple (physician)
John Dalrymple FRS was an English ophthalmologist who was born in Norwich, the son of William Dalrymple. In 1827 he graduated from the University of Edinburgh, and subsequently became an eye surgeon at the Royal London Ophthalmic Hospital.He was elected assistant-surgeon in 1832 and full surgeon...
(1803–1852).
Other eye signs described within the symptomology of Graves' disease are Stellwag's sign
Stellwag's sign
Stellwag's sign is a sign of infrequent or incomplete blinking associated with exophthalmos or Graves orbitopathy. It is accompanied by Dalrymple's sign, which is a retraction of the upper eyelids resulting in an apparent widening of the palpebral opening....
(rare blinking), Rosenbach's sign (tremor of the eyelids), and Jelink's sign (hyperpigmentation of the eyelid).
Dalrymple sign is lid retraction in primary gaze.