Cyclin B
Encyclopedia
Cyclin B is a member of the cyclin
family.
Cyclin B is a mitotic
cyclin. The amount of cyclin B (which binds to Cdk1
) and the activity of the cyclin B-Cdk complex rise through the cell cycle
until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present). The complex of Cdk and cyclin B is called maturation promoting factor
or mitosis promoting factor (MPF).
Cyclin
Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase enzymes.- Function :...
family.
Cyclin B is a mitotic
Mitosis
Mitosis is the process by which a eukaryotic cell separates the chromosomes in its cell nucleus into two identical sets, in two separate nuclei. It is generally followed immediately by cytokinesis, which divides the nuclei, cytoplasm, organelles and cell membrane into two cells containing roughly...
cyclin. The amount of cyclin B (which binds to Cdk1
Cdk1
Cyclin dependent kinase 1 also known as Cdk1 or cell division control protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation. It has been highly studied in the budding yeast S. cerevisiae, and the fission yeast S....
) and the activity of the cyclin B-Cdk complex rise through the cell cycle
Cell cycle
The cell cycle, or cell-division cycle, is the series of events that takes place in a cell leading to its division and duplication . In cells without a nucleus , the cell cycle occurs via a process termed binary fission...
until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present). The complex of Cdk and cyclin B is called maturation promoting factor
Maturation promoting factor
Maturation-promoting factor is a heterodimeric protein composed of cyclin B and cyclin-dependent kinase that stimulates the mitotic and meiotic cell cycles...
or mitosis promoting factor (MPF).