Cornea plana 2
Encyclopedia
Cornea plana 2 is an extremely rare congenital hereditary deformity of the eye surface, leading to severe decrease in corneal curvature. There is evidence that cornea plana 2 is caused by mutations in KERA
gene encoding keratocan.
KERA (gene)
Keratocan also known as keratan sulfate proteoglycan keratocan is a protein that in humans is encoded by the KERA gene.Keratan sulfate proteoglycans are members of the small leucine-rich proteoglycan family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of...
gene encoding keratocan.
External links
- Congenital Clouding of the Cornea - eMedicine; by Noah S Scheinfeld, MD, JD, FAAD and Benjamin D Freilich, MD, FACS