CobB
Encyclopedia
CobB is a bacterial protein
that belongs to the sirtuin
family, a broadly conserved family of NAD+
-dependent protein deacetylase
s.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that belongs to the sirtuin
Sirtuin
Sirtuin or Sir2 proteins are a class of proteins that possess either histone deacetylase or mono-ribosyltransferase activity. Sirtuins regulate important biological pathways in bacteria, archaea and eukaryotes...
family, a broadly conserved family of NAD+
Nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide, abbreviated NAD, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.In metabolism, NAD is involved...
-dependent protein deacetylase
Protein deacetylase
Protein deacetylase; any enzyme that removes acetyl groups from lysine amino acids in proteins.The main ones are histone deacetylases and sirtuins ....
s.