Coagulopathy

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Coagulopathy

Coagulopathy is a medical term for a defect in the body's mechanism for blood

Blood

Blood is a specialized bodily fluid that delivers necessary substances to the body's Cell s ? such as nutrients and oxygen ? and transports waste products away from those same cells....
clotting.

e there are several possible causes they generally result in excessive bleeding and a lack of clotting.

ired causes of coagulopathy include anticoagulation with warfarin

Warfarin

Warfarin is an anticoagulant. It was initially marketed as a pesticide against rats and mice, and is still popular for this purpose, although more potent poisons such as brodifacoum have since been developed....
, liver failure

Liver failure

Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease , and indicates that the liver has sustained severe damage ....
, and disseminated intravascular coagulation

Disseminated intravascular coagulation

Disseminated intravascular coagulation , also known as consumptive coagulopathy, is a pathological activation of coagulation mechanisms that happens in response to a variety of diseases....
. Additionally, the haemotoxic venom from certain species of snake

Snake

Snakes are elongate legless carnivore reptiles of the suborder Serpentes that can be distinguished from legless lizards by their lack of eyelids and external ears....
s can cause this condition e.g.

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Causes

While there are several possible causes they generally result in excessive bleeding and a lack of clotting.

Acquired

Acquired causes of coagulopathy include anticoagulation with warfarin

Warfarin

Liver failure

Disseminated intravascular coagulation

Snake

Bothrops

Bothrops is a genus of venomous snake Crotalinaes found in Central America, South America. The generic name is derived from the Greek words bothros and ops that mean "pit" and "eye" or "face"; an allusion to the heat-sensitive loreal pit organs....
, rattlesnakes and other species

Species

In biology, a species is one of the basic units of biological classification and a taxonomic rank. A species is often defined as a group of organisms capable of interbreeding and producing fertile offspring....
of viper

Viperidae

The Viperidae are a family of venomous snakes found all over the world, except in Australia and Madagascar. All have relatively long hinged fangs that permit deep penetration and injection of venom....
.

Autoimmune causes of acquired coagulation disorders

There are autoimmune causes of coagulation disorders. They include acquired antibodies to coagulation factors; termed inhibitors of coagulation. The main inhibitor is directed against Factor VIII Another example is antiphospholipid syndrome

Antiphospholipid syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome is a disorder of coagulation, which causes blood clots in both artery and veins, as well as pregnancy-related complications such as miscarriage, Premature birth, or severe preeclampsia....
.

Coagulopathy

Causes

Acquired

Autoimmune causes of acquired coagulation disorders

See also