Chicken ovalbumin upstream promoter-transcription factor
Encyclopedia
The chicken ovalbumin upstream promoter transcription factor (COUP-TFs) proteins are members of the nuclear receptor
Nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules...

 family of intracellular
Intracellular
Not to be confused with intercellular, meaning "between cells".In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".It is used in contrast to extracellular...

 transcription factor
Transcription factor
In molecular biology and genetics, a transcription factor is a protein that binds to specific DNA sequences, thereby controlling the flow of genetic information from DNA to mRNA...

s. There are two variants of the COUP-TFs, labeled as COUP-TFI
COUP-TFI
COUP-TF1 also known as NR2F1 is a protein that in humans is encoded by the NR2F1 gene...

and COUP-TFII
COUP-TFII
COUP-TFII , also known as NR2F2 is a protein that in humans is encoded by the NR2F2 gene...

encoded by the and genes respectively.

COUP-TFs play critical roles in the development of organisms.
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