Castleton Avenue is an east-west road in Staten Island

Staten Island

Staten Island is a borough of New York City, New York, United States, located in the southwest part of the city. Staten Island is separated from New Jersey by the Arthur Kill and the Kill Van Kull, and from the rest of New York by New York Bay...

. It runs from Victory Boulevard

Victory Boulevard

Victory Boulevard is a major thoroughfare on Staten Island, measuring approximately 8.0 miles and stretching from the west shore community of Travis to the upper east shore communities of St. George and Tompkinsville. In the late 1940s, the portion of Victory Boulevard between Richmond Avenue and...

 in the West New Brighton

New Brighton, Staten Island

New Brighton, formerly an independent village, is today a neighborhood located on the North Shore of Staten Island in New York City, USA. The neighborhood comprises an older industrial and residential harbor front area along the Kill Van Kull west of St. George.The village of New Brighton was...

 neighborhood to Nicholas Avenue in the Port Richmond

Port Richmond, Staten Island

Port Richmond is a neighborhood situated on the North Shore of Staten Island, one of the five boroughs of New York City, United States. It is along the waterfront of the Kill Van Kull, with the southern terminus of the Bayonne Bridge serving as the boundary between it and Mariners Harbor, the...

 neighborhood.

Castleton Avenue is served by the s46 local bus and the S96 limited.

Landmarks include the original Staten Island Hospital

Staten Island University Hospital

Staten Island University Hospital is a major tertiary referral center on Staten Island, in New York City.SIUH is a two-campus, 785-bed teaching hospital consisting of a North Campus, a South Campus, and the now closed Concord Campus....

 site, Richmond University Medical Center

Richmond University Medical Center

Richmond University Medical Center is a hospital in West New Brighton, Staten Island in New York City. The hospital occupies the buildings that were formerly St. Vincent's Medical Center, which closed in 2006.-History:...

, the West Brighton Houses, and the MTA NYCTA Castleton Bus Depot.

At approximately 3.4 miles (5.5 km) long, the artery runs parallel to the Staten Island Expressway, and Forest Avenue.