Carbolabs
Encyclopedia
Carbolabs, Inc., a chemistry company specializing in reactions utilizing phosgene
Phosgene
Phosgene is the chemical compound with the formula COCl2. This colorless gas gained infamy as a chemical weapon during World War I. It is also a valued industrial reagent and building block in synthesis of pharmaceuticals and other organic compounds. In low concentrations, its odor resembles...

, was founded by Joe Karabinos in 1967. Originally located in the basement of his home in Bethany, Connecticut
Bethany, Connecticut
Bethany is a town in New Haven County, Connecticut, United States. The population was 5,040 at the 2000 census. Bethany was first settled in 1717 but it was not until May 1832 that Bethany separated from Woodbridge to become incorporated as a town. This slightly remote, sparsely populated,...

, it wasn't until the following year that the business was moved into its own dedicated building. The company was purchased by Sigma Aldrich in 1998. In 2008 operations at the Bethany site were discontinued and were subsequently moved to the Sheboygan Falls, Wisconsin
Sheboygan Falls, Wisconsin
Sheboygan Falls is a city in Sheboygan County, Wisconsin, United States whose population was 6,772 at the 2000 census. It is included in the Sheboygan, Wisconsin Metropolitan Statistical Area.-Geography:...

 Sigma Aldrich manufacturing facility. Carbolabs uses phosgene to produce a wide array of chemicals including isocyanates, chloroformates, and isonitriles, although some reactions not involving phosgene such as the production of the fluorinating reagent DAST are also part of their established chemistries. As a subsidiary of Sigma Aldrich, a number of Aldrich products still bear "A Carbolabs Product" on their label.
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