CXCL7
Encyclopedia
Chemokine ligand 7 (CXCL7) is a human gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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The encoded protein, Chemokine (C-X-C motif) ligand is a small cytokine
Cytokine
Cytokines are small cell-signaling protein molecules that are secreted by the glial cells of the nervous system and by numerous cells of the immune system and are a category of signaling molecules used extensively in intercellular communication...

 belonging to the CXC chemokine
Chemokine
Chemokines are a family of small cytokines, or proteins secreted by cells. Their name is derived from their ability to induce directed chemotaxis in nearby responsive cells; they are chemotactic cytokines...

 family. It is an isoform of Beta-Thromboglobulin
Beta-thromboglobulin
Beta-thromboglobulin is a protein that is stored in alpha-granules of platelets and released in large amounts after platelet activation.It is a type of Chemokine ligand 7.-Actions:...

 or Pro-Platelet basic protein (PPBP).

It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix
Extracellular matrix
In biology, the extracellular matrix is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.Extracellular...

, glucose metabolism and synthesis of plasminogen activator
Plasminogen activator
A plasminogen activator is a serine protease which converts plasminogen to plasmin, thus promoting fibrinolysis.Types include:* Tissue plasminogen activator* Urokinase...

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Further reading

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