CRTC1
Encyclopedia
CREB
CREB
CREB is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements , thereby increasing or decreasing the transcription of the downstream genes....

-regulated transcription coactivator 1 (CRTC1)
, previously referred to as TORC1 (Transducer Of Regulated CREB activity 1, not to be confused with the unrelated target of rapamycin complex 1 (TORC1)) is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the CRTC1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

. It is expressed in a limited number of tissues that inclide fetal brain and liver and adult heart, skeletal muscles, liver and salivary glands.

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