CD72
Encyclopedia
CD72 also known in murine biology as Lyb-2, is a protein active in the immune system
Immune system
An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own...

 of animals. It consists of two identical halves, each of about 39-43 daltons
KD
KD may refer to:* Kapal DiRaja, ship prefix used in the Royal Malaysian Navy* Kappa Delta, a National Panhellenic sorority* Katamari Damacy, a video game by Namco* Kawasaki disease* Kentucky Derby* Ketogenic diet...

, and is a C-type lectin
Lectin
Lectins are sugar-binding proteins that are highly specific for their sugar moieties. They play a role in biological recognition phenomena involving cells and proteins. For example, some viruses use lectins to attach themselves to the cells of the host organism during infection...

. Its primarily locus of expression is B-cells, where it appears to mediate aspects of B-cell - T-cell interaction. It is a ligand for CD5
CD5 (protein)
CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase and are potentially self-reactive...

.

External links

  • Dr. Jane Parnes lab at Stanford University
    Stanford University
    The Leland Stanford Junior University, commonly referred to as Stanford University or Stanford, is a private research university on an campus located near Palo Alto, California. It is situated in the northwestern Santa Clara Valley on the San Francisco Peninsula, approximately northwest of San...

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