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CD68

 

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CD68



 
 
CD68 (Cluster of Differentiation 68
Cluster of differentiation

The cluster of differentiation is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. CD molecules can act in numerous ways, often acting as receptor or ligand important to the cell....
) is a glycoprotein
Glycoprotein

Not to be confused with peptidoglycan or proteoglycan.Glycoproteins are proteins that contain oligosaccharide chains covalently attached to their Peptide side-chains....
 which binds to low density lipoprotein
Low density lipoprotein

Low-density lipoprotein is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL is one of the five major groups of lipoproteins; these groups include chylomicrons, very low-density lipoprotein , intermediate-density lipoprotein , low-density lipoprotein, and high-density lipoprotein ,...
.

It is expressed on monocyte
Monocyte

Monocyte is a type of leukocyte, part of the human body's immune system. Monocytes have two main functions in the immune system: replenish resident macrophages and dendritic cells under normal states, and in response to inflammation signals, monocytes can move quickly to sites of infection in the tissues and divide/differentiate into mac...
s/macrophage
Macrophage

Macrophages are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter....
s.

The mouse equivalent is called "macrosialin".








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CD68 (Cluster of Differentiation 68
Cluster of differentiation

The cluster of differentiation is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. CD molecules can act in numerous ways, often acting as receptor or ligand important to the cell....
) is a glycoprotein
Glycoprotein

Not to be confused with peptidoglycan or proteoglycan.Glycoproteins are proteins that contain oligosaccharide chains covalently attached to their Peptide side-chains....
 which binds to low density lipoprotein
Low density lipoprotein

Low-density lipoprotein is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL is one of the five major groups of lipoproteins; these groups include chylomicrons, very low-density lipoprotein , intermediate-density lipoprotein , low-density lipoprotein, and high-density lipoprotein ,...
.

It is expressed on monocyte
Monocyte

Monocyte is a type of leukocyte, part of the human body's immune system. Monocytes have two main functions in the immune system: replenish resident macrophages and dendritic cells under normal states, and in response to inflammation signals, monocytes can move quickly to sites of infection in the tissues and divide/differentiate into mac...
s/macrophage
Macrophage

Macrophages are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter....
s.

The mouse equivalent is called "macrosialin".

Use in pathology

CD68 is used to identify macrophages and giant cell
Giant cell

A giant cell is a mass formed by the union of several distinct cells. It can arise in response to an infection or foreign body.Types include:...
s.

See also

  • Cluster of differentiation
    Cluster of differentiation

    The cluster of differentiation is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. CD molecules can act in numerous ways, often acting as receptor or ligand important to the cell....


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