Butamirate
Encyclopedia
Butamirate is a cough suppressant.
A study found it to bind to the dextromethorphan
-binding site in guinea pig brain with high affinity.
As a 2-(2-diethylaminoethoxy)ethyl ester it is chemically related to Oxeladin
and Pentoxyverine
, which are in the same class. (The Oxeladin has an additional ethyl group in it's carboxylic acid, the Pentoxyverine has both ethyl groups of Oxeladin replaced by one cyclopentyl in the same place.)
It acts on the cough center in the medulla oblongata
.
A study found it to bind to the dextromethorphan
Dextromethorphan
Dextromethorphan is an antitussive drug. It is one of the active ingredients in many over-the-counter cold and cough medicines, such as Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, and others, including generic labels. Dextromethorphan has also found other uses in medicine, ranging...
-binding site in guinea pig brain with high affinity.
As a 2-(2-diethylaminoethoxy)ethyl ester it is chemically related to Oxeladin
Oxeladin
Oxeladin is a cough suppressant. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is free of risk of dependence or addiction...
and Pentoxyverine
Pentoxyverine
Pentoxyverine or carbetapentane is an antitussive commonly used for cough associated with illnesses like common cold. It is sold over-the-counter in the United States as Solotuss, or in combination with other medications, especially decongestants...
, which are in the same class. (The Oxeladin has an additional ethyl group in it's carboxylic acid, the Pentoxyverine has both ethyl groups of Oxeladin replaced by one cyclopentyl in the same place.)
It acts on the cough center in the medulla oblongata
Medulla oblongata
The medulla oblongata is the lower half of the brainstem. In discussions of neurology and similar contexts where no ambiguity will result, it is often referred to as simply the medulla...
.
See also
- OxeladinOxeladinOxeladin is a cough suppressant. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is free of risk of dependence or addiction...
- PentoxyverinePentoxyverinePentoxyverine or carbetapentane is an antitussive commonly used for cough associated with illnesses like common cold. It is sold over-the-counter in the United States as Solotuss, or in combination with other medications, especially decongestants...
- DimethoxanateDimethoxanateDimethoxanate is a cough suppressant....
- PipazetatePipazetatePipazetate is a cough suppressant....