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Bromo-Seltzer

Bromo-Seltzer

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Bromo-Seltzer is an antacid
Antacid
An antacid is a substance which neutralizes stomach acidity.-Mechanism of action:Antacids perform a neutralization reaction, increasing the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gastrointestinal mucosa, they signal pain to the central nervous...

 used to relieve pain occurring together with heartburn
Heartburn
Heartburn, also known as pyrosis or acid indigestion is a burning sensation in the chest, just behind the breastbone or in the epigastrium...

, upset stomach, or acid indigestion. Originally produced by inventor Isaac E. Emerson's Emerson Drug Company of Baltimore, Maryland, Bromo-Seltzer is sold in the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 in the form of effervescent granules which must be mixed with water before ingestion
Ingestion
Ingestion is the consumption of a substance by an organism. In animals, it normally is accomplished by taking in the substance through the mouth into the gastrointestinal tract, such as through eating or drinking...

.

In the days of classic radio, it was known for its slogan which was repeated rhythmically in imitation of a railroad steam engine: "BRO-mo-Selt-zer, BRO-mo-Selt-zer, ..." There is also a clock tower in Baltimore
Baltimore
Baltimore is the largest independent city in the United States and the largest city and cultural center of the US state of Maryland. The city is located in central Maryland along the tidal portion of the Patapsco River, an arm of the Chesapeake Bay. Baltimore is sometimes referred to as Baltimore...

, Maryland
Maryland
Maryland is a U.S. state located in the Mid Atlantic region of the United States, bordering Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware to its east...

, known as the Bromo-Seltzer Tower
Emerson Bromo-Seltzer Tower
The Emerson Bromo-Seltzer Tower was erected in 1911 at the corner of Eutaw and Lombard Streets in Baltimore, Maryland. It was designed by Joseph Evans Sperry and was constructed by Bromo-Seltzer inventor "Captain" Isaac E. Emerson. It was the tallest building in Baltimore from 1911 until 1923...

, which has the name written on the face of the clock in lieu of the hours. Patterned on the Palazzo Vecchio
Palazzo Vecchio
The Palazzo Vecchio is the town hall of Florence, Italy. This massive, Romanesque, crenellated fortress-palace is among the most impressive town halls of Tuscany...

 in Florence
Florence
Florence is the capital city of the Italian region of Tuscany and of the province of Florence. It is the most populous city in Tuscany, with approximately 370,000 inhabitants, expanding to over 1.5 million in the metropolitan area....

, Italy
Italy
Italy , officially the Italian Republic languages]] under the European Charter for Regional or Minority Languages. In each of these, Italy's official name is as follows:;;;;;;;;), is a unitary parliamentary republic in South-Central Europe. To the north it borders France, Switzerland, Austria and...

, it is listed on the National Register of Historic Places
National Register of Historic Places
The National Register of Historic Places is the United States government's official list of districts, sites, buildings, structures, and objects deemed worthy of preservation...

.

The product took its name from a component of the original formula, sodium bromide
Sodium bromide
Sodium bromide is an inorganic compound with the formula NaBr. It is a high-melting white, crystalline solid that resembles sodium chloride. It is a widely used source of the bromide ion and has many applications.-Synthesis, structure, reactions:...

; it contained 3.2 mEq/teaspoon of this active ingredient. Bromide
Bromide
A bromide is a chemical compound containing bromide ion, that is bromine atom with effective charge of −1. The class name can include ionic compounds such as caesium bromide or covalent compounds such as sulfur dibromide.-Natural occurrence:...

s are a class of tranquilizers that were withdrawn from the American market in 1975 due to their toxicity. Their sedative effect probably accounted for Bromo-Seltzer's popularity as a hangover
Hangover
A hangover describes the sum of unpleasant physiological effects following heavy consumption of alcoholic beverages. The most commonly reported characteristics of a hangover include headache, nausea, sensitivity to light and noise, lethargy, dysphoria, diarrhea and thirst, typically after the...

 remedy. Early formulas also used Acetanilide as the analgesic
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....

, a known poisonous substance.

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