Baicalin
Encyclopedia
Baicalin is a flavone, a type of flavonoid. It is found in several species in the genus Scutellaria, including Scutellaria lateriflora
Scutellaria lateriflora
Scutellaria lateriflora, also known as Blue Skullcap, Hoodwort, Virginian Skullcap, Mad-dog Skullcap is a hardy perennial herb native to North America. It is a member of the mint family. It has an upright habit, growing 60 to 80 centimeters in maximum height. It is a wetland-loving species and...

(blue skullcap). There are 10 mg/g baicalin in Scutellaria galericulata
Scutellaria galericulata
Common Skullcap , also known as Marsh Skullcap or Hooded Skullcap, is a hardy perennial herb native to northern areas of the Northern Hemisphere, including Europe, Asia, and much of North America. It is a member of the mint family...

(common skullcap) leaves. It is a component of Chinese medicinal herb Huang-chin (Scutellaria baicalensis
Scutellaria baicalensis
Scutellaria baicalensis is a species of flowering plant in the Lamiaceae family.-Medicinal uses:...

).

It is one of the active ingredients of Sho-Saiko-To
Sho-saiko-to
Sho-Saiko-To , also known as Minor Bupleurum Formula and Xiao Chai Hu Tang in Chinese, is a herbal supplement, believed to enhance liver health. Sho-Saiko-To is a widely used prescription drug in Japan and is a listed formula in Japanese Kampo. There are currently ongoing clinical trials for...

, an herbal supplement believed to enhance liver health.

Baicalin is the glucuronide
Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond...

 of baicalein
Baicalein
Baicalein is a flavone, a type of flavonoid, originally isolated from the roots of Scutellaria baicalensis. It is also reported in Oroxylum indicum or Indian trumpetflower...

.

Baicalin is a known prolyl endopeptidase
Prolyl endopeptidase
Prolyl endopeptidase or prolyl oligopeptidase, sometimes post-proline cleaving enzyme) is a large cytosolic enzyme that belongs to a distinct class of serine peptidases. It was first described in the cytosol of rabbit brain as an oligopeptidase, which degrades the nonapeptide bradykinin at the...

 inhibitor and affects the GABA receptors
GABA receptor
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid , the chief inhibitory neurotransmitter in the vertebrate central nervous system...

.
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