Astilbin
Encyclopedia
Astilbin is a flavanonol
Flavanonol
The flavanonols are a class of flavonoids that use the 3-hydroxy-2,3-dihydro-2-phenylchromen-4-one backbone.Some examples include:* Taxifolin...

, a type of flavonoid. Astilbin is the (2R-trans)-isomer; neoisoastilbin is the (2S-cis)-isomer and isoastilbin is the (2R-cis)-isomer.

Astilbin can be found in St John's wort
St John's wort
St John's wort is the plant species Hypericum perforatum, and is also known as Tipton's Weed, Chase-devil, or Klamath weed....

 (Hypericum perforatum, Clusiaceae, subfamily Hypericoideae, formerly often considered a full family Hypericaceae), in Dimorphandra mollis
Dimorphandra mollis
Dimorphandra mollis, the Fava d'anta, is a tree species in the genus of Dimorphandra. It is a plant of the Cerrado vegetation of Brazil.Fava d'anta contains astilbin and rutin....

(Fava d'anta, Fabaceae), in the leaves of Harungana madagascariensis
Harungana madagascariensis
Harungana madagascariensis is a species of flowering plants in the family Hypericaceae and the sole member of the genus Harungana. It is found in tropical Africa and Mauritius. The plant has red sap. It is used as a treatment for ringworm in Liberia....

(Hypericaceae), in the rhizome of Astilbe thunbergii, in the root of Astilbe odontophylla(Saxifragaceae), in the rhizone of Smilax glabra (Chinaroot, Smilacaceae) and in the bark of Hymenaea martiana
Hymenaea martiana
Hymenaea martiana is a tree species in the genus Hymenaea found in Brazil and Paraguay.-Chemicals:...

. It can be isolated from Kohki tea
Kohki tea
Kohki tea is a Japanese herbal drink very high in antioxidant activity. Kohki tea has been sold over the counter for centuries and is standardized to contain Astilbin and toxifolin. Kohki Tea extract promotes fat burning and prolongs the fat burning process....

 processed from Engelhardtia chrysolepis (huang-qui).

Uses

Astilbin can act as an insecticide against Anticarsia gemmatalis
Anticarsia gemmatalis
Anticarsia gemmatalis is a tropical species of caterpillar and moth that migrates north each season. The species can commonly be found in the Gulf states, north as far as Wisconsin. The adults have wings that are grayish brown, crossed with brown or black zigzag lines. The caterpillars are black or...

and Spodoptera frugiperda. It shows in vitro antibacterial activity and activity on burn wound healing. Astilbin is used in traditional Chinese medicine.

Related compounds

3'-O-Methylastilbin shows an immunosuppressive activity against contact dermatitis
Contact dermatitis
Contact dermatitis is a term for a skin reaction resulting from exposure to allergens or irritants . Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight....

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