Actinoplanes
Encyclopedia
Actinoplanes are a genus in the family Actinoplanaceae. They have aerial mycelia and spherica, motile spores.
Actinoplanes produces the pharmaceutically important compounds valienamine
, teicoplanin
and ramoplanin
.
Actinoplanes produces the pharmaceutically important compounds valienamine
Valienamine
Valienamine is a C-7 aminocyclitol found as a substructure of pseudooligosaccharides such as acarbose or validamycins. It can be found in Actinoplanes species.It is an intermediate formed by microbial degradation of validamycins....
, teicoplanin
Teicoplanin
Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. It is a glycopeptide antibiotic extracted from Actinoplanes teichomyceticus, with a similar...
and ramoplanin
Ramoplanin
Ramoplanin is a glycolipodepsipeptide antibiotic drug derived from strain ATCC 33076 of Actinoplanes.-Mechanism:It exerts its bacteriocidal effect by inhibiting cell wall biosynthesis, acting by inhibiting the transglycosylation step of peptidoglycan synthesis.-Uses:Its development has been...
.