Abadie's sign
Encyclopedia
Abadie's sign of exophthalmic goiter is Spasm
Spasm
In medicine a spasm is a sudden, involuntary contraction of a muscle, a group of muscles, or a hollow organ, or a similarly sudden contraction of an orifice. It is sometimes accompanied by a sudden burst of pain, but is usually harmless and ceases after a few minutes...

 of the Levator Palpebrae Superioris muscle with retraction of the upper lid (so that sclera
Sclera
The sclera , also known as the white or white of the eye, is the opaque , fibrous, protective, outer layer of the eye containing collagen and elastic fiber. In the development of the embryo, the sclera is derived from the neural crest...

 is visible above cornea
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...

) seen in Graves-Basedow disease
Graves-Basedow disease
Graves' disease is an autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones...

 which, together with exophthalmos
Exophthalmos
Exophthalmos is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral or unilateral . Measurement of the degree of exophthalmos is performed using an exophthalmometer...

 causes the bulging eyes appearance.

It is named for Jean Marie Charles Abadie
Jean Marie Charles Abadie
Jean Marie Charles Abadie was a French ophthalmologist who was a native of Saint-Gaudens. He became a hospital intern in 1868 and a medical doctor in 1870...

.
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