APPBP1
Encyclopedia
NEDD8-activating enzyme E1 regulatory subunit is a protein
that in humans is encoded by the NAE1 gene
.
with UBE1C
, TRIP12
and Amyloid precursor protein
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the NAE1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
APPBP1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with UBE1C
UBE1C
This enzyme contains an E2 binding domain, which resembles ubiquitin, and recruits the catalytic core of the E2 enzyme UBE2M in a similar manner to that in which ubiquitin interacts with ubiquitin binding domains.-Interactions:...
, TRIP12
TRIP12
Probable E3 ubiquitin-protein ligase TRIP12 is an enzyme that in humans is encoded by the TRIP12 gene.-Further reading:...
and Amyloid precursor protein
Amyloid precursor protein
Amyloid precursor protein is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export...
.