AHSA2
Encyclopedia
AHSA2 also known as AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) is a human gene
which encodes a protein
which acts as co-chaperone
of Hsp90
(heat shock protein
90). AHSA2 and the related AHSA1
belongs to the AHA (Activator of Hsp90 ATPase) family of stress-regulated proteins that bind directly to Hsp90 and are required for Hsp90-dependent activation of client proteins.
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
which encodes a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
which acts as co-chaperone
Co-chaperone
Co-chaperones are proteins that assist chaperones in protein folding and other functions.-List of Co-chaperones:*Aha1*auxilin*BAG1*CAIR-1/Bag-3*CDC37/p50*Chp1*Cysteine string protein *Cyp40*Djp1*DnaJ*E3/E4-ubiquitin ligase*FKBP52*GAK*GroES...
of Hsp90
Hsp90
Hsp90 is a molecular chaperone and is one of the most abundant proteins expressed in cells. It is a member of the heat shock protein family, which is upregulated in response to stress...
(heat shock protein
Heat shock protein
Heat shock proteins are a class of functionally related proteins involved in the folding and unfolding of other proteins. Their expression is increased when cells are exposed to elevated temperatures or other stress. This increase in expression is transcriptionally regulated...
90). AHSA2 and the related AHSA1
AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1 is an enzyme that in humans is encoded by the AHSA1 gene.-Interactions:AHSA1 has been shown to interact with Heat shock protein 90kDa alpha , member A1.-Further reading:...
belongs to the AHA (Activator of Hsp90 ATPase) family of stress-regulated proteins that bind directly to Hsp90 and are required for Hsp90-dependent activation of client proteins.