Offseason

• October 15, 1965: Warren Spahn
  Warren Spahn
  Warren Edward Spahn was an American Major League Baseball left-handed pitcher. He played his entire 21-year baseball career in the National League. He won 20 games each in 13 seasons, including a 23-7 record when he was age 42...
  
   was released by the Giants.
• December 2, 1965: Randy Hundley
  Randy Hundley
  Cecil Randolph "Randy" Hundley Jr. is a former American professional baseball player and coach. He played in Major League Baseball as a catcher for the San Francisco Giants , Chicago Cubs , Minnesota Twins , and the San Diego Padres...
  
   and Bill Hands
  Bill Hands
  William Alfred "Bill" Hands, Jr. , is a former professional baseball player who pitched in the major leagues from 1965-1975. Hands' best season came in 1969 with the Chicago Cubs, when he won 20 games....
  
   traded to the Chicago Cubs
  Chicago Cubs
  The Chicago Cubs are a professional baseball team located in Chicago, Illinois. They are members of the Central Division of Major League Baseball's National League. They are one of two Major League clubs based in Chicago . The Cubs are also one of the two remaining charter members of the National...
  
   for Lindy McDaniel
  Lindy McDaniel
  Lyndall Dale McDaniel, known as Lindy is a right-handed former relief pitcher in Major League Baseball who had a 21-year career from 1955 to 1975. During McDaniel's career he witnessed approximately 3,500 major league games , had more than 300 teammates, and played under eight different managers...
  
   and Don Landrum
  Don Landrum
  Donald Leroy Landrum was an American professional baseball player, an outfielder in the Major Leagues from to for the San Francisco Giants, Chicago Cubs, St. Louis Cardinals and Philadelphia Phillies. Born in Santa Rosa, California, Landrum attended Mt. Diablo High School in Concord, California...
  
  .

Opening Day lineup

• Jesús Alou
  Jesús Alou
  Jesús María Rojas Alou is a former Major League Baseball outfielder. During a 17-year baseball career, he played for the San Francisco Giants , Houston Astros , Oakland Athletics , and New York Mets...
  
  
• Tito Fuentes
  Tito Fuentes
  Rigoberto "Tito" Fuentes Peat is a retired second baseman who played for 13 seasons in the Major Leagues between 1965 and 1978...
  
  
• Len Gabrielson
• Tom Haller
  Tom Haller
  Thomas Frank Haller was an American professional baseball player and baseball executive. He played as a catcher in Major League Baseball with the San Francisco Giants , Los Angeles Dodgers and Detroit Tigers...
  
  
• Jim Ray Hart
  Jim Ray Hart
  James Ray Hart , is a retired third baseman in Major League Baseball. He played for the National League's San Francisco Giants from 1963 to 1973 and the American League's New York Yankees in 1973 and 1974. Hart batted and threw right-handed...
  
  
• Hal Lanier
  Hal Lanier
  Harold Clifton Lanier is a former infielder, coach and manager in Major League Baseball. From through , Lanier played for the San Francisco Giants and New York Yankees...
  
  
• Juan Marichal
  Juan Marichal
  Juan Antonio Marichal Sánchez is a former right-handed pitcher in Major League Baseball. Playing for the San Francisco Giants most of his career, Marichal was known for his high leg kick, pinpoint control and intimidation tactics, which included aiming pitches directly at the opposing batters'...
  
  
• Willie Mays
  Willie Mays
  Willie Howard Mays, Jr. is a retired American professional baseball player who played the majority of his major league career with the New York and San Francisco Giants before finishing with the New York Mets. Nicknamed The Say Hey Kid, Mays was elected to the Baseball Hall of Fame in 1979, his...
  
  
• Willie McCovey
  Willie McCovey
  Willie Lee McCovey , nicknamed "Mac", "Big Mac", and "Stretch", is a former Major League Baseball first baseman. He played nineteen seasons for the San Francisco Giants, and three more for the San Diego Padres and Oakland Athletics, between and...
  
  

Notable transactions

• May 8, 1966: Orlando Cepeda
  Orlando Cepeda
  Orlando Manuel Cepeda Pennes is a former Puerto Rican Major League Baseball first baseman.Cepeda was born to a poor family. His father, Pedro Cepeda, was a baseball player in Puerto Rico, which influenced his interest in the sport from a young age. His first contact with professional baseball was...
  
   was traded by the Giants to the St. Louis Cardinals
  St. Louis Cardinals
  The St. Louis Cardinals are a professional baseball team based in St. Louis, Missouri. They are members of the Central Division in the National League of Major League Baseball. The Cardinals have won eleven World Series championships, the most of any National League team, and second overall only to...
  
   for Ray Sadecki
  Ray Sadecki
  Raymond Michael Sadecki is a former Major League Baseball pitcher. A left-hander, Sadecki pitched for the St...
  
  .
• June 10, 1966: Bob Shaw
  Bob Shaw (baseball)
  Robert John Shaw was a Major League Baseball pitcher.His career lasted a decade, and he pitched for the Detroit Tigers, Chicago White Sox, Kansas City Athletics, Milwaukee Braves, San Francisco Giants, New York Mets, and Chicago Cubs. He won 18 games with the American League pennant-winning White...
  
   was purchased from the Giants by the New York Mets
  New York Mets
  The New York Mets are a professional baseball team based in the borough of Queens in New York City, New York. They belong to Major League Baseball's National League East Division. One of baseball's first expansion teams, the Mets were founded in 1962 to replace New York's departed National League...
  
  .

Roster

Starters by position

Other batters

Starting pitchers

Other pitchers

Relief pitchers

Farm system