11-Dehydrothromboxane B2
Encyclopedia
11-Dehydrothromboxane B2 (or 11-dehydro-TXB2) is produced from the breakdown of thromboxane A2
. It is released by activated platelets and urine levels of 11-dehydro-TXB2 can be used to monitor the response to aspirin
therapy when used to prevent heart disease and in diseases where platelet activation is prominent.
Thromboxane A2
Thromboxane A2 is a thromboxane. It is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. This is achieved by mediating expression of the glycoprotein complex GP IIb/IIIa in the cell membrane of...
. It is released by activated platelets and urine levels of 11-dehydro-TXB2 can be used to monitor the response to aspirin
Aspirin
Aspirin , also known as acetylsalicylic acid , is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. It was discovered by Arthur Eichengrun, a chemist with the German company Bayer...
therapy when used to prevent heart disease and in diseases where platelet activation is prominent.