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319 Arius travels to Nicomedia at the invitation of Eusebius, after having been accused of heresy and condemned by Alexander, the Patriarch of Alexandria. This gave rise to the Arian Controversy.
321 A synod in Alexandria condemns Arianism.
346 The Visigoths are converted to Arianism by Wulfila.
347 Council of Sardica is held. This council attempted to resolve the Arian controversy, and laid down ground rules for Bishops.
359 The Council of Rimini is held. Its purpose was to, once again, try to resolve the Arian controvery. Given Saint Jerome's comment that, "The whole world groaned in astonishment to find itself Arian", it appears to have failed.
364 Valens (an Arian) begins the first antipagan persecutions.
373 Valens is converted to Arianism and orders the persecution of orthodox Christians.
375 Gratian, advised by Ambrose, begins a systematic persecution of the pagans. He confiscates the fortunes of the temples and adds the money to the Imperial Treasury, and removes the Altar of Victory from the Senate. He proscribes Arianism and Donatism.
380 Roman Emperors Theodosius I and Gratianus declare that the patriarchs of Rome and Alexandria hold primacy (above especially the one of Constantinople), implicitly rejecting Arianism in favor of orthodox Christianity.
381 Council of Aquileia: under the guidance of Ambrose, the chief Arianist bishops Palladius and Secundadius are deposed.
384 Ambrosius refuses the Roman Empress Justina's request for a church in Milan where she can worship according to her Arian belief.
587 Reccared, king of the Visigoths, renounces Arianism and adopts Catholicism.
589 Third Council of Toledo called by King Reccared of the Visigoths kingdom renounces Arianism and embraces Catholicism.
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