"Ebene" redirects here. For the city in Mauritius, see Ebene CityEbene City is a city on the island nation of Mauritius, 15 km south of the capital, Port Louis.Construction began in November, 2001, with the city being promoted as a new information technology hub for Mauritius and as a link between African and Asian markets -- as a result is referred to as Ebene...
.
Anadenanthera peregrina, also known as
Yopo,
Jopo,
Cohoba,
Mopo,
Nopo,
Parica or
Calcium Tree, is a perennial tree of the
AnadenantheraAnadenanthera is a genus of South American trees in the Legume family, Fabaceae. The genus contains two to four species, including A. colubrina and A. peregrina...
genus native to the
CaribbeanThe Caribbean is a crescent-shaped group of islands more than 2,000 miles long separating the Gulf of Mexico and the Caribbean Sea, to the west and south, from the Atlantic Ocean, to the east and north...
and
South AmericaSouth America is a continent situated in the Western Hemisphere, mostly in the Southern Hemisphere, with a relatively small portion in the Northern Hemisphere. The continent is also considered a subcontinent of the Americas. It is bordered on the west by the Pacific Ocean and on the north and east...
. It grows up to 20 m tall, having a thorny bark. Its flowers are pale yellow to white and spherical. It is not listed as being a
threatened speciesThreatened species are any speciesg animals, plants, fungi, etc.) which are vulnerable to endangerment in the near future.The World Conservation Union is the foremost authority on threatened species, and treats threatened species not as a single category, but as a group of three categories,...
. It is an
entheogenAn entheogen , in the strict sense, is a psychoactive substance used in a religious, shamanic, or spiritual context. Historically, entheogens were mostly derived from plant sources and have been used in a variety of traditional religious contexts...
used in healing ceremonies and
ritualA ritual is a set of actions, performed mainly for their symbolic value. It may be prescribed by a religion or by the traditions of a community. The term usually excludes actions which are arbitrarily chosen by the performers....
s. It is also a well known source of dietary
calciumCalcium is the chemical element with the symbol Ca and atomic number 20. It has an atomic mass of 40.078 amu. Calcium is a soft gray alkaline earth metal, and is the fifth-most-abundant element by mass in the Earth's crust...
.
Related species
The usage complex of yopo is almost identical to that of a related tree,
Anadenanthera colubrina, commonly known as
Cebíl or
Vilca. The beans of
A. colubrina have a similar chemical makeup as
Anadenanthera peregrina, with their primary constituent being 5-OH-DMT (
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
).
Botanical varieties
- Anadenanthera peregrina var. falcata
Anadenanthera peregrina var. falcata is a timber tree native to Paraguay and Cerrado vegetation in Brazil, specially in Mato Grosso, Mato Grosso do Sul, Minas Gerais, and São Paulo. This plant is also used as an ornamental and medicinal plant....
- Anadenanthera peregrina var. peregrina
Anadenanthera peregrina var. peregrina is a tree in the Fabaceae family. It is native to Guyana, Venezuela, Brazil, Colombia and it is also found in the Caribbean.-Entheogen:In South America, Anadenanthera peregrina var...
Wood
The wood from
A. peregrina is very hard and it is good for making
furnitureFurniture is the mass noun for the movable objects intended to support various human activities such as seating and sleeping in beds, to hold objects at a convenient height for work using horizontal surfaces above the ground, or to store things...
. It has a
JankaThe Janka hardness test measures the resistance of a type of wood to withstand denting and wear. It measures the force required to embed an steel ball into wood to half the ball's diameter. This method leaves an indentation...
rating of 3700 lb. and a density of around 0.86 g/cm³.
Toxicity
The beans (sometimes called seeds) and falling leaves are hallucinogenic and are toxic to
cattleCattle are the most common type of large domesticated ungulates. They are a prominent modern member of the subfamily Bovinae, are the most widespread species of the genus Bos, and are most commonly classified collectively as Bos primigenius...
.
Chemical compounds
Chemical compoundA chemical compound is a pure chemical substance consisting of two or more different chemical elements that can be separated into simpler substances by chemical reactions. Chemical compounds have a unique and defined chemical structure; they consist of a fixed ratio of atoms that are held together...
s contained in
A. peregrina include:
- 1,2,3,4-Tetrahydro-6-methoxy-2,9-dimethyl-beta-carboline
β-Carboline is an organic amine that is the prototype of a class of compounds known as β-carbolines.-Pharmacology:...
, Plant
- 1,2,3,4-Tetrahydro-6-methoxy-2-methyl-beta-carboline, Plant
- 5-Methoxy-N,N-dimethyltryptamine
5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
, Bark
- 5-Methoxy-N-methyltryptamine, Bark
- Bufotenin
Bufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
, Plant, beans
- Bufotenin
Bufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
N-oxide, Fruit, beans

- Catechol, Plant
- Homoorientine, Leaf
- Leucoanthocyanin, Plant
- Leucopelargonidol, Plant
- N,N-Dimethyltryptamine
N,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
, Fruit, beans, pods, bark
- N,N-Dimethyltryptamine-oxide, Fruit
- N-Methyltryptamine, Bark
- Orientin
Orientin is a flavone, a chemical flavonoid-like compound found in the passion flower, the Açaí palm, in Adonis vernalis and Anadenanthera peregrina. Orientin is also reported in millets and in the Phyllostachys nigra bamboo leaves....
, Leaf
- Saponarentin, Leaf
- Viterine, Leaf
The bark and leaves contain
tanninA tannin is an astringent, bitter plant polyphenolic compound that binds to and precipitates proteins and various other organic compounds including amino acids and alkaloids.The term tannin refers to the use of...
and the beans contain
saponinSaponins are a class of chemical compounds, one of many secondary metabolites found in natural sources, with saponins found in particular abundance in various plant species...
.
Traditional usage
Archaeological evidence shows
Anadenanthera beans have been used as hallucinogens for thousands of years. The oldest clear evidence of use comes from smoking pipes made of puma bone (Felis Concolor) found with
Anadenanthera beans at Inca Cueva, a site in the northwest of
HumahuacaHumahuaca is a city in the province of Jujuy, Argentina. It has 11,369 inhabitants as per the , and is the principal town of the Department of Humahuaca...
in the
PunaPuna may refer to:* Puna grassland, a type of grassland in the central part of the high Andes* Puna , the king of Hiti-marama or of Vavau in the Tuamotu legend of Rata* Puna , a type of wind in the Andes...
border of the Province of Jujuy,
ArgentinaArgentina , officially the Argentine Republic , is the second largest country in South America by land area, after Brazil. It is constituted as a federation of 23 provinces and an autonomous city, Buenos Aires...
. The pipes were found to contain the hallucinogen
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
, one of the compounds found in
Anadenanthera beans. Radiocarbon testing of the material gave a date of 2130 B.C., suggesting
Anadenanthera use as a hallucinogen is over 4000 years old. Snuff trays and tubes similar to those commonly used for yopo were found in the central Peruvian coast dating back to 1200 B.C., suggesting that
insufflationInsufflation is the practice of inhaling a substance. Insufflation has limited medical use, but is a common route of administration with many respiratory drugs used to treat conditions in the lungs and paranasal sinus .The technique is common for many recreational drugs and is also used for some...
of
Anadenanthera beans is a more recent method of use. Archaeological evidence of insufflation use within the period 500-1000 A.D. in northern Chile has been reported.
Some indigenous peoples of the
OrinocoThe Orinoco is one of the longest rivers in South America at . Its drainage basin, sometimes called the Orinoquia, covers , with 76.3% of it in Venezuela and the remainder in Colombia...
basin in
ColombiaColombia, officially the Republic of Colombia , is a unitary constitutional republic comprising thirty-two departments. The country is located in northwestern South America, bordered to the east by Venezuela and Brazil; to the south by Ecuador and Peru; to the north by the Caribbean Sea; to the...
,
VenezuelaVenezuela , officially called the Bolivarian Republic of Venezuela , is a tropical country on the northern coast of South America. It borders Colombia to the west, Guyana to the east, and Brazil to the south...
and possibly in the southern part of the
BrazilBrazil , officially the Federative Republic of Brazil , is the largest country in South America. It is the world's fifth largest country, both by geographical area and by population with over 192 million people...
ian
AmazonThe Amazon Basin is the part of South America drained by the Amazon River and its tributaries that drains an area of about , or roughly 40 percent of South America. The basin is located in the countries of Bolivia, Brazil, Colombia, Ecuador, Guyana, Peru, and Venezuela...
make use of yopo snuff for spiritual healing. Yopo snuff was also widely used in ceremonial contexts in the
CaribbeanThe Caribbean is a crescent-shaped group of islands more than 2,000 miles long separating the Gulf of Mexico and the Caribbean Sea, to the west and south, from the Atlantic Ocean, to the east and north...
area, including
CubaThe Republic of Cuba is an island nation in the Caribbean. The nation of Cuba consists of the main island of Cuba, the Isla de la Juventud, and several archipelagos. Havana is the largest city in Cuba and the country's capital. Santiago de Cuba is the second largest city...
and La Española, up to the Spanish Conquest.
Yopo snuff is usually blown into the user's nostrils by another person through
bambooBamboo is a group of perennial evergreens in the true grass family Poaceae, subfamily Bambusoideae, tribe Bambuseae. Giant bamboos are the largest members of the grass family....
tubes or sometimes snuffed by the user using bird bone tubes. Blowing is more effective as this method allows more powder to enter the nose and is said to be less irritating. In some areas the unprocessed ground beans are snuffed or smoked producing a much weaker effect with stronger physical symptoms. Some tribes use yopo along with
Banisteriopsis caapiBanisteriopsis caapi, also known as Ayahuasca, Caapi or Yage, is a South American jungle vine of the family Malpighiaceae. It is used to prepare Ayahuasca, a decoction that has a long history of entheogenic uses as a medicine and "plant teacher" among the indigenous peoples of the Amazon Rainforest...
to increase and prolong the visionary effects, creating an experience similar to that of
ayahuascaAyahuasca is any of various psychoactive infusions or decoctions prepared from the Banisteriopsis spp. vine, usually mixed with the leaves of dimethyltryptamine-containing species of shrubs from the Psychotria genus...
.
Snuff preparation
To make the
psychedelicThe term psychedelic is derived from the Greek words ψυχή and δηλοῦν , translating to "soul-manifesting". A psychedelic experience is characterized by the striking perception of aspects of one's mind previously unknown, or by the creative exuberance of the mind liberated from its ostensibly...
snuff called yopo, the black beans from the bean pods of these trees are first toasted until the beans pop like
popcornPopcorn, or popping corn, is corn which expands from the kernel and puffs up when heated. Corn is able to pop because, like sorghum, quinoa and millet, its kernels have a hard moisture-sealed hull and a dense starchy interior. This allows pressure to build inside the kernel until an explosive...
breaking the bean's
huskHusk in botany is the outer shell or coating of a seed. It often refers to the leafy outer covering of an ear of maize as it grows on the plant. Literally, a husk or hull includes the protective outer covering of a seed, fruit or vegetable...
. The roasting process facilitates removal of the
huskHusk in botany is the outer shell or coating of a seed. It often refers to the leafy outer covering of an ear of maize as it grows on the plant. Literally, a husk or hull includes the protective outer covering of a seed, fruit or vegetable...
and makes the beans easier to grind into a powder. The bean's
huskHusk in botany is the outer shell or coating of a seed. It often refers to the leafy outer covering of an ear of maize as it grows on the plant. Literally, a husk or hull includes the protective outer covering of a seed, fruit or vegetable...
is usually removed because it is difficult to powderise and adds unnecessary volume. The bean is then ground with a
mortar and pestleA mortar and pestle is a tool used to crush, grind, and mix solid substances . The pestle is a heavy bat-shaped object, the end of which is used for crushing and grinding. The mortar is a bowl, typically made of hard wood, ceramic or stone...
into a powder and mixed with a natural form of
calcium hydroxideCalcium hydroxide, traditionally called slaked lime, is an inorganic compound with the chemical formula Ca2. It is a colourless crystal or white powder and is obtained when calcium oxide is mixed, or "slaked" with water. It has many names including hydrated lime, builders lime, slack lime, cal, or...
(
limeLimestone is a sedimentary rock composed largely of the minerals calcite and aragonite, which are different crystal forms of calcium carbonate . Many limestones are composed from skeletal fragments of marine organisms such as coral or foraminifera....
) or
calcium oxideCalcium oxide , commonly known as quicklime or burnt lime, is a widely used chemical compound. It is a white, caustic, alkaline crystalline solid at room temperature....
(from certain types of ashes,
calcinedCalcination is a thermal treatment process applied to ores and other solid materials to bring about a thermal decomposition, phase transition, or removal of a volatile fraction. The calcination process normally takes place at temperatures below the melting point of the product materials...
shells, etc.). This mix is then moistened to a consistency similar to
breadBread is a staple food prepared by cooking a dough of flour and water and often additional ingredients. Doughs are usually baked, but in some cuisines breads are steamed , fried , or baked on an unoiled frying pan . It may be leavened or unleavened...
doughDough is a paste made out of any cereals or leguminous crops by mixing flour with a small amount of water and/or other liquid. This process is a precursor to making a wide variety of foodstuffs, particularly breads and bread-based items , flatbreads, noodles, pastry, and similar items)...
, using a small amount of water. If calcium oxide is used, the water will react with it to form calcium hydroxide. Once moistened, it is kneaded into a ball for several minutes. After kneading, it is then left to sit for several hours to several days, depending on the local customs. During this period most of the excess calcium hydroxide reacts with the
carbon dioxideCarbon dioxide is a naturally occurring chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom...
in the air to form less caustic
calcium carbonateCalcium carbonate is a chemical compound with the formula CaCO3. It is a common substance found in rocks in all parts of the world, and is the main component of shells of marine organisms, snails, coal balls, pearls, and eggshells. Calcium carbonate is the active ingredient in agricultural lime,...
(
carbonatationCarbonatation is a chemical reaction in which calcium hydroxide reacts with carbon dioxide and forms insoluble calcium carbonate:The process of forming a carbonate is sometimes referred to as "carbonation", although this term usually refers to the process of dissolving carbon dioxide in...
).
Active constituents
Bufotenin
The beans have been found to contain up to 7.4%
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
. At up to 7.4 % (74 mg per gram) bufotenin, an effective 40 mg dose of insufflated bufotenin requires little more than 0.5 grams of beans.
The intraperitoneal of bufotenin is between 200–300 mg/kg (in rodents) with death occurring by respiratory arrest. The LD
50 in rodents amounts to between 10,000 mg and 15,000 mg for a small 50 kg (110 lb) adult. Based on the intraperitoneal LD
50 for rodents, at 74 mg per gram, it would require approximately 135 grams of beans to reach the estimated LD
50of bufotenin for a 50 kg (110 lb) adult. Human intravenous tests using
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
suggest the LD
50 may be much lower in humans with subjects showing signs of peripheral toxicity (purple face,
tachycardiaTachycardia comes from the Greek words tachys and kardia . Tachycardia typically refers to a heart rate that exceeds the normal range for a resting heart rate...
, difficulty breathing, etc.) at doses as little as 8 mg in some subjects. Free base bufotenin when insufflated, taken sublingually, orally, or intrarectally, elicits strong hallucinogenic effects with far less side effects.
Dimethyltryptamine and 5-MeO-DMT
The effects of insufflated
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
and
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
are relatively short acting, lasting about 1 hour, while the effects of insufflated yopo typically last 2–3 hours. Of the three main compounds present, only insufflated bufotenine lasts 2–3 hours. Claims of Anadenanthera peregrina containing DMT and 5-MeO-DMT as their main active ingredients are based on rare cases where these compounds are found in larger quantities than bufotenine. Typical acid base extraction techniques utilizing strong bases such as sodium hydroxide solution will exclude bufotenin from the extraction, in favor of
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
and
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
. It is believed that such extractions have contributed to the misconception that bufotenin is a minor alkaloid in yopo. The majority of the extractions confirm that
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
is primarily responsible for the effects of yopo with the other compounds usually appearing in quantities too small to produce noticeable effects in an average yopo dose of 5-10 grams.
The beans have been found to contain up to only 0.04%
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
and 0.16%
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
. The leaves and bark also contain small amounts of
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
,
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
and related compounds.
At up to 0.04% (0.4 mg per gram)
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
, an effective light 5 mg dose of insufflated
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
(5-MeO-DMT dosage, Erowid.org) would require over 12 grams of beans. It would be extremely difficult to insufflate the 12 grams of beans (approximately 72 beans) needed to reach the active dose of
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
present in the beans. The body would begin to develop tolerance to
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
before being able to insufflate all 12 grams of beans. Individual sensitivity to
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
varies. It's been documented that the threshold dose in some individuals is as much as 10 mg insufflated requiring over 24 grams of beans for an effective dose of
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
.
At up to 0.16% (1.6 mg per gram)
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
, an effective 40 mg dose of insufflated
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
would require 25 grams or more. It’s likely to be impossible to insufflate the 25 grams of beans required to reach the active dose of
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
present in the beans. An extract of 25 grams of beans could contain up to 1,850 mg of
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
, a potentially dangerous dose of
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
. With insufflated free-base
bufoteninBufotenin , or 5-hydroxy-dimethyltryptamine , is a tryptamine related to the neurotransmitter serotonin...
, the maximum published safe dose used has been 100 mg.
Unlike bufotenin, both
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
and
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
are relatively unstable and begin to degrade rather quickly. Schultes and colleges (1977) examined a 120 year old bean collection and found 0.6% bufotenin with no
DMTN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
or
5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
present at all. They also examined a batch of beans that contained all three compounds when fresh, but found only bufotenin in the beans after only two years of storage.
Oral usage
When taken orally by some tribes in South America, small amounts are often combined with alcoholic chichas (maize based beer). Moderate doses are unpleasant, producing nausea and vomiting. The beans were a main ingredient in bilca tauri, an oral purge medicine used to induce ritual vomiting once a month. Large amounts are not usually consumed orally; as many tribes believe oral use is dangerous.
Use with MAOIs
Some South American tribes have been documented to use various bean preparations along with
Banisteriopsis caapiBanisteriopsis caapi, also known as Ayahuasca, Caapi or Yage, is a South American jungle vine of the family Malpighiaceae. It is used to prepare Ayahuasca, a decoction that has a long history of entheogenic uses as a medicine and "plant teacher" among the indigenous peoples of the Amazon Rainforest...
, a herb containing MAOIs. Typically
Banisteriopsis caapi is chewed in the mouth while the Anadenanthera beans are snuffed or smoked. Occasionally
Banisteriopsis caapi is found mixed in with the snuff. Moderate amounts of
Banisteriopsis caapi will effectively double the potency of the Anadenanthera beans. Larger amounts of
Banisteriopsis caapi will not only double the potency of
Anadenanthera beans but also alter the quality of the experience, producing a more relaxed dreamy effect, with possible increased nausea. There are no well documented reports of the beans being used as a major component in ingestion of
ayahuascaAyahuasca is any of various psychoactive infusions or decoctions prepared from the Banisteriopsis spp. vine, usually mixed with the leaves of dimethyltryptamine-containing species of shrubs from the Psychotria genus...
, a therapeutic tea made with
Banisteriopsis caapi.
See also
- List of plants of Caatinga vegetation of Brazil
- Anadenanthera colubrina
- Psychedelic plants
A list of plants that are used for psychedelic drugs. Some of them have been used for thousands of years for religious purposes. The plants are listed according to the substances they contain.-THC:Cannabis is a popular psychedelic plant...
General references
- Jonathan Ott
Jonathan Ott is an ethnobotanist, writer, translator, publisher, natural products chemist and botanical researcher in the area of entheogens and their cultural and historical uses, and helped coin the term "entheogen".-Writings:...
- Shamanic Snuffs or Entheogenic Errhines (2001) ISBN 1-888755-02-4
- Richard Evans Schultes
Richard Evans Schultes may be considered the father of modern ethnobotany, for his studies of indigenous peoples' uses of plants, including especially entheogenic or hallucinogenic plants , for his lifelong collaborations with chemists, and...
- Plants of the Gods (1992) ISBN 0-89281-979-0
External links