Xanthosis is a type of skin-related disease where one has an abnormal yellow discolouration of the skin, resulting from the accumulation of cholesterol

Cholesterol

Cholesterol is a complex isoprenoid. Specifically, it is a waxy steroid of fat that is produced in the liver or intestines. It is used to produce hormones and cell membranes and is transported in the blood plasma of all mammals. It is an essential structural component of mammalian cell membranes...

 within the skin cells. It can also have such affect that there may be a yellowish discoloration of degenerating tissues

Tissue (biology)

Tissue is a cellular organizational level intermediate between cells and a complete organism. A tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function. These are called tissues because of their identical functioning...

, especially seen in malignant neoplasms. It was the championship word used in the 1995 Scripps National Spelling Bee

Scripps National Spelling Bee

The Scripps National Spelling Bee is a highly competitive annual spelling bee in the United States, with participants from other countries as well. It is run on a not-for-profit basis by The E. W...

.