Working Formulation
Encyclopedia
The Working Formulation is an obsolete classification of non-Hodgkin lymphoma
Non-Hodgkin lymphoma
The non-Hodgkin lymphomas are a diverse group of blood cancers that include any kind of lymphoma except Hodgkin's lymphomas. Types of NHL vary significantly in their severity, from indolent to very aggressive....

s published in 1982. It has since been replaced by other lymphoma
Lymphoma
Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

 classifications, the latest published by the WHO
World Health Organization
The World Health Organization is a specialized agency of the United Nations that acts as a coordinating authority on international public health. Established on 7 April 1948, with headquarters in Geneva, Switzerland, the agency inherited the mandate and resources of its predecessor, the Health...

 in 2008, but is still used by cancer agencies for compilation of lymphoma statistics.

Low Grade
  • Malignant Lymphoma, small lymphocytic (chronic lymphocytic leukemia
    Chronic lymphocytic leukemia
    B-cell chronic lymphocytic leukemia , also known as chronic lymphoid leukemia , is the most common type of leukemia. Leukemias are cancers of the white blood cells . CLL affects B cell lymphocytes. B cells originate in the bone marrow, develop in the lymph nodes, and normally fight infection by...

    )
  • Malignant Lymphoma, follicular
    Follicular lymphoma
    Follicular lymphoma is the most common of the indolent non-Hodgkin's lymphomas, and the second most common form of non-Hodgkin's lymphomas overall. It is defined as a lymphoma of follicle center B-cells , which has at least a partially follicular pattern...

    , predominantly small cleaved cell
  • Malignant Lymphoma, follicular
    Follicular lymphoma
    Follicular lymphoma is the most common of the indolent non-Hodgkin's lymphomas, and the second most common form of non-Hodgkin's lymphomas overall. It is defined as a lymphoma of follicle center B-cells , which has at least a partially follicular pattern...

    , mixed (small cleaved and large cell
    Large cell
    Large cell is a term used in oncology. It does not refer to a particular type of cell; rather it refers to cells that are larger than would be normally expected for that type...

    )


Intermediate grade
  • Malignant Lymphoma, follicular
    Follicular lymphoma
    Follicular lymphoma is the most common of the indolent non-Hodgkin's lymphomas, and the second most common form of non-Hodgkin's lymphomas overall. It is defined as a lymphoma of follicle center B-cells , which has at least a partially follicular pattern...

    , predominantly large cell
  • Malignant Lymphoma, diffuse, small cleaved cell
  • Malignant Lymphoma, diffuse, mixed small and large cell
  • Malignant Lymphoma, diffuse, large cell


High grade
  • Malignant Lymphoma, large cell, immunoblastic
  • Malignant Lymphoma, lymphoblastic
  • Malignant Lymphoma, small non-cleaved cells (Burkitt's lymphoma
    Burkitt's lymphoma
    Burkitt's lymphoma is a cancer of the lymphatic system...

    )


Miscellaneous
  • Composite
  • Mycosis fungoides
    Mycosis fungoides
    -External links:* * *...

  • Histiocytic
  • Extramedullary plasmacytoma
  • Unclassifiable
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