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Transversion

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Transversion

In molecular biology

Molecular biology

Molecular biology is the study of biology at a molecule level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry....
, transversion refers to the substitution of a purine

Purine

Purine is a heterocyclic compound aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Purines, including substituted purines and their tautomers, are the most widely distributed kind of nitrogen-containing heterocycle in nature....
for a pyrimidine

Pyrimidine

Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring....
or vice versa. It can only be reverted by a spontaneous reversion. Because this type of mutation changes the chemical structure dramatically, the consequences of this change tend to be more severe and less common than that of transitions

Transition (genetics)

In genetics, a transition is a mutation changing a purine to another purine nucleotide or a pyrimidine to another pyrimidine nucleotide . Approximately two out of every three single nucleotide polymorphisms are transitions....
.Transversions can be caused by ionizing radiation and alkylating agents.

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In molecular biology

Molecular biology

Molecular biology is the study of biology at a molecule level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry....
, transversion refers to the substitution of a purine

Purine

Purine is a heterocyclic compound aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Purines, including substituted purines and their tautomers, are the most widely distributed kind of nitrogen-containing heterocycle in nature....
for a pyrimidine

Pyrimidine

Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring....
or vice versa. It can only be reverted by a spontaneous reversion. Because this type of mutation changes the chemical structure dramatically, the consequences of this change tend to be more severe and less common than that of transitions

Transition (genetics)

In genetics, a transition is a mutation changing a purine to another purine nucleotide or a pyrimidine to another pyrimidine nucleotide . Approximately two out of every three single nucleotide polymorphisms are transitions....
.Transversions can be caused by ionizing radiation and alkylating agents.

See also

Transition
Transition (genetics)

In genetics, a transition is a mutation changing a purine to another purine nucleotide or a pyrimidine to another pyrimidine nucleotide . Approximately two out of every three single nucleotide polymorphisms are transitions....

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