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Tolazoline

 

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Tolazoline



 
 
Tolazoline is a non-selective competitive
Competitive antagonist

A competitive antagonist is a receptor antagonist that binds to a Receptor but d






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Tolazoline is a non-selective competitive
Competitive antagonist

A competitive antagonist is a receptor antagonist that binds to a Receptor but does not activate the receptor. The antagonist will compete with available agonist for receptor binding sites on the same receptor....
 a-adrenergic receptor
Adrenergic receptor

The adrenergic receptors are a class of G protein-coupled receptors that are targets of the catecholamines. Adrenergic Receptor s specifically bind and are activated by their endogenous ligands, the catecholamines adrenaline and noradrenaline ....
 antagonist
Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that does not provoke a biological response itself upon binding to a Receptor , but blocks or dampens agonist-mediated responses....
. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis
Acrocyanosis

Acrocyanosis refer to a persistent blue or cyanotic discoloration of the digits, most commonly occurring in the hands although also occurring in the face and feet as well....
). It has also been used successfully as an antidote to reverse the severe peripheral vasoconstriction which can occur as a result of overdose with certain 5-HT2A
5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor which belongs to the serotonin receptor family and is a GPCR ....
 agonist
Agonist

An agonist is a term used to describe a type of Ligand or drug that binds and alters the activity of a Receptor . The ability to alter the activity of a receptor, also known as the agonist's efficacy is a property that distinguishes it from receptor antagonist, a type of receptor ligand which also binds a receptor but which does not alter t...
 drugs such as LSD
LSD

Lysergic acid diethylamide, LSD, LSD-25, or acid, is a semisynthetic psychedelic drug of the ergoline family. Its unusual psychological effects, which include visuals of colored patterns behind the eyes in the mind, a sense of time distorting, and crawling geometric patterns, have made it one of the most widely known psyched...
, DOB
2,5-Dimethoxy-4-bromoamphetamine

DOB, also known as Brolamfetamine and Bromo-DMA, is a psychedelic Psychedelics, dissociatives and deliriants and a substituted amphetamine of the phenethylamine class of compounds, which can be used as an entheogen....
 and Bromodragonfly and can lead to gangrene
Gangrene

For the American football team nicknamed "Gang Green," see New York Jets.Gangrene is a complication of necrosis characterized by the decay of biological tissues, which become black and malodorous....
 if untreated.

It is however most commonly used in veterinary medicine
Veterinary medicine

Veterinary medicine is that branch of medical science,which deals with the study of diagnosis,treatment and prevention of diseases in companion,domestic, exotic, wildlife and production animals....
, to reverse xylazine
Xylazine

Xylazine is a medication that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other large mammals....
-induced sedation
Sedation

Sedation is a medical procedure involving the administration of sedative drugs, generally to facilitate a medical procedure with local anaesthesia....
.