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Thomas Hodgkin

 
Thomas Hodgkin

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Thomas Hodgkin



 
 
Thomas Hodgkin (August 17, 1798 - April 5, 1866) was a British
United Kingdom

The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom , the UK or Britain,is a sovereign state located off the northwestern coast of continental Europe....
 physician
Physician

A physician, medical practitioner, doctor of medicine, or medical doctor practices medicine, and is concerned with maintaining or restoring human health through the study, diagnosis, and treatment of disease and injury....
 and considered one of the most prominent pathologists
Pathology

Pathology is the study and diagnosis of disease through examination of Organ , tissue , bodily fluids and whole bodies . The term also encompasses the related science study of disease processes, called General pathology....
 of his time and a pioneer in preventive medicine
Preventive medicine

Preventive medicine or preventive care is measures taken to prevent illness or injury, rather than curing them. This type of care is best exemplified by hand washing and immunizations....
. He is now best known for the first account of Hodgkin's disease, a form of lymphoma
Lymphoma

Lymphoma is a type of cancer that originates in lymphocytes of the immune system. They often originate in lymph nodes, presenting as an enlargement of the node ....
 and blood disease, in 1832. Hodgkin's work marked the beginning of times when a pathologist was actively involved in the clinical process. He was a contemporary of Thomas Addison
Thomas Addison

Thomas Addison was a renowned 19th-century English physician and scientist. He is traditionally regarded as one of the "great men" of Guy's Hospital in London....
  and Richard Bright
Richard Bright (physician)

Richard Bright was an England physician and early pioneer in the research of Nephrology.He was born in Bristol, Gloucestershire , the third son of Sarah and Richard Bright Sr., a wealthy merchant and banker....
 at Guy's Hospital
Guy's Hospital

Guy's Hospital is a large National Health Service hospital in the London Borough of Southwark in south east London, England. It is administratively a part of Guy's and St Thomas' NHS Foundation Trust....
.

as Hodgkin was born to a Quaker family in Pentonville
Pentonville

Pentonville is an area of north-central London in the London Borough of Islington, centred on the Pentonville Road. Pentonville was part of the ancient parish of Clerkenwell, and was incorporated into the Metropolitan Borough of Finsbury by the London Government Act 1899....
, St.






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Thomas Hodgkin (August 17, 1798 - April 5, 1866) was a British
United Kingdom

The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom , the UK or Britain,is a sovereign state located off the northwestern coast of continental Europe....
 physician
Physician

A physician, medical practitioner, doctor of medicine, or medical doctor practices medicine, and is concerned with maintaining or restoring human health through the study, diagnosis, and treatment of disease and injury....
 and considered one of the most prominent pathologists
Pathology

Pathology is the study and diagnosis of disease through examination of Organ , tissue , bodily fluids and whole bodies . The term also encompasses the related science study of disease processes, called General pathology....
 of his time and a pioneer in preventive medicine
Preventive medicine

Preventive medicine or preventive care is measures taken to prevent illness or injury, rather than curing them. This type of care is best exemplified by hand washing and immunizations....
. He is now best known for the first account of Hodgkin's disease, a form of lymphoma
Lymphoma

Lymphoma is a type of cancer that originates in lymphocytes of the immune system. They often originate in lymph nodes, presenting as an enlargement of the node ....
 and blood disease, in 1832. Hodgkin's work marked the beginning of times when a pathologist was actively involved in the clinical process. He was a contemporary of Thomas Addison
Thomas Addison

Thomas Addison was a renowned 19th-century English physician and scientist. He is traditionally regarded as one of the "great men" of Guy's Hospital in London....
  and Richard Bright
Richard Bright (physician)

Richard Bright was an England physician and early pioneer in the research of Nephrology.He was born in Bristol, Gloucestershire , the third son of Sarah and Richard Bright Sr., a wealthy merchant and banker....
 at Guy's Hospital
Guy's Hospital

Guy's Hospital is a large National Health Service hospital in the London Borough of Southwark in south east London, England. It is administratively a part of Guy's and St Thomas' NHS Foundation Trust....
.

Life

Thomas Hodgkin was born to a Quaker family in Pentonville
Pentonville

Pentonville is an area of north-central London in the London Borough of Islington, centred on the Pentonville Road. Pentonville was part of the ancient parish of Clerkenwell, and was incorporated into the Metropolitan Borough of Finsbury by the London Government Act 1899....
, St. James Parish, Middlesex
Middlesex

Middlesex , from the Old English Middelseaxe , is one of the 39 Historic counties of England of England and the List of counties of England by area in 1831....
. He received private education and, in September 1819 he was admitted to St. Thomas's and Guy's Medical School, now part of King's College London
King's College London

King's College London is a United Kingdom higher education institution and co-founding constituent college of the University of London. Founded by George IV of the United Kingdom and the Arthur Wellesley, 1st Duke of Wellington in 1829, its royal charter is predated, in England, only by those of the Universities of University of Oxford and Un...
. He also studied at the University of Edinburgh
University of Edinburgh

The University of Edinburgh founded in 1582, is an internationally renowned centre for teaching and research in Edinburgh, Scotland, United Kingdom....
, Scotland
Scotland

conventional_long_name = ScotlandAlba|common_name= Scotland|image_flag = Flag of Scotland.svg|flag_width = 130px...
. In 1821, he went to Italy
Italy

Italy , officially the Italian Republic , is a country located on the Italian Peninsula in Southern Europe and on the two largest islands in the Mediterranean Sea, Sicily and Sardinia....
 and France
France

France , officially the French Republic , is a country whose Metropolitan France is located in Western Europe and that also comprises various Overseas departments and territories of France....
, where he learned to work with the stethoscope
Stethoscope

The stethoscope is a acoustic medicine device for auscultation, or listening to eth internal sounds of an animal body. It is stom often used to listen to heart sounds....
, a recent invention of René Laënnec
René Laennec

Ren?-Th?ophile-Hyacinthe Laennec was a French physician. He invented the stethoscope in 1816, while working at the H?pital Necker and pioneered its use in diagnosing various chest conditions....
. In 1823, Hodgkin qualified for his M.D. at Edinburgh
Edinburgh

Edinburgh ; is the Capital city of Scotland, a position it has held since 1437. It is the seventh largest city in the United Kingdom and the second largest Scottish City status in the United Kingdom after Glasgow....
 with a thesis on the physiological mechanisms of absorption in animals.

Hodgkin was a close friend of Sir Moses Montefiore
Moses Montefiore

Sir Moses Haim Montefiore, 1st Baronet, Kt was one of the most famous United Kingdom Jews of the 19th century. Montefiore was a finance, banker, philanthropist and Sheriff of London....
 and he accompanied him to Palestine in 1866. There he contracted Dysentery
Dysentery

Dysentery is a disorder of the digestive system that results in severe diarrhea containing mucus and/or blood in the feces. If untreated, Dysentery can be fatal....
 and died on 4 April 1866 and buried in Jaffa
Jaffa

File:Jaffa StPeter church.jpgJaffa is an ancient port city believed to be one of the oldest in the world.Jaffa is located south of Tel Aviv, Israel on the Mediterranean Sea....
.

There is a Blue plaque
Blue plaque

In the United Kingdom, a blue plaque is a permanent sign installed in a public place to commemorate a link between that location and a famous person or event....
 on his house in Bedford Square
Bedford Square

Bedford Square is a square in the Bloomsbury district of the London Borough of Camden in London, England.It was built between 1775 and 1783 as an upper middle class residential area, and has had many distinguished residents, including John Scott, 1st Earl of Eldon, one of Britain's longest serving and most celebrated Lord Chancellors, who...
, London.

Works

Blue Plaque Thomas Hodgkin
Hodgkin described the disease that bears his name (Hodgkin's lymphoma
Hodgkin's lymphoma

Hodgkin's lymphoma, also known as Hodgkin's disease is a type of lymphoma . It was named after Thomas Hodgkin, who first described abnormalities in the lymph system in 1832....
) in 1832, in a paper titled On Some Morbid Appearances of the Absorbent Glands and Spleen . He received 33 years later the eponym
Eponym

An eponym is a person, whether real or fictitious, after whom a particular toponym, ethnonym, regnal year, discovery, or other item is named or thought to be named....
 through the recognition of British physician Samuel Wilks
Samuel Wilks

Sir Samuel Wilks , British physician and biographer.Wilks studied medicine at Guy's Hospital from 1844 to 1846. After graduation he was hired as a physician to the Surrey Infirmary ....
, who rediscovered the disease. It is a malignancy that produces enlargement of lymphoid tissue, spleen
Spleen

The spleen is an organ found in all vertebrate animals. In humans, the spleen is located in the abdomen of the body, where it functions in the destruction of redundant red blood cells, and holds a reservoir of blood....
, and liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....
, with invasion of other tissues. A more benign form is called Hodgkin’s paragranuloma, while a more invasive form is called Hodgkin's sarcoma.

He published as a book his Lectures on Morbid Anatomy in 1836 and 1840. His greatest contribution to the teaching of pathology, however, was made in 1829, with his two volumed work entitled The Morbid Anatomy of Serous and Mucous Membranes, which became a classic in modern pathology.

Hodgkin was one of the earliest defenders of preventive medicine, having published On the Means of Promoting and Preserving Health in book form in 1841. Among other early observations were the first description of acute appendicitis
Appendicitis

Appendicitis is a condition characterized by inflammation of the Vermiform appendix. It is a medical emergency. All cases require removal of the inflamed appendix, either by laparotomy or laparoscopy....
, of the biconcave format of red blood cells and the striation of muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
 fibers.

External links



  • ODNB article by Amalie M. Kass, ‘Hodgkin, Thomas (1798–1866)’, Oxford Dictionary of National Biography, Oxford University Press, 2004 , accessed 22 Sept 2007.