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Synergy



 
 
Synergy (from the Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
 , meaning working together) is the term used to describe a situation where different entities cooperate advantageously for a final outcome. Simply defined, it means that the whole is greater than the sum of its parts. The essence of synergy is to value differences - to respect them, to build on strenghts, to compensate for weaknesses.

The opposite of synergy is antagonism
Antagonism

Antagonism is hostility that results in active resistance, opposition, or contentiousness.Additionally, it may refer to:*Antagonism , where the involvement of multiple agents reduce their overall effect...
, the phenomenon where two agents in combination have an overall effect that is less than that predicted from their individual effects.

Synergy can also mean:
synergism occurs when drug
Drug

A drug, broadly speaking, is any chemical substance that, when absorbed into the body of a living organism, alters normal bodily function....
s can interact in ways that enhance or magnify one or more effects, or side effects, of those drugs.






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Encyclopedia


Synergy (from the Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
 , meaning working together) is the term used to describe a situation where different entities cooperate advantageously for a final outcome. Simply defined, it means that the whole is greater than the sum of its parts. The essence of synergy is to value differences - to respect them, to build on strenghts, to compensate for weaknesses.

The opposite of synergy is antagonism
Antagonism

Antagonism is hostility that results in active resistance, opposition, or contentiousness.Additionally, it may refer to:*Antagonism , where the involvement of multiple agents reduce their overall effect...
, the phenomenon where two agents in combination have an overall effect that is less than that predicted from their individual effects.

Synergy can also mean:
  • A mutually advantageous conjunction.
  • A dynamic state in which combined action is favored over the sum of individual component actions.
  • Behavior of whole systems unpredicted by the behavior of their parts taken separately. More accurately known as emergent behavior.
  • The cooperative action of two or more stimuli or drugs.

Drug synergy

Drug synergism occurs when drug
Drug

A drug, broadly speaking, is any chemical substance that, when absorbed into the body of a living organism, alters normal bodily function....
s can interact in ways that enhance or magnify one or more effects, or side effects, of those drugs. This is sometimes exploited in combination preparations, such as codeine
Codeine

Codeine or methylmorphine is an opiate used for its analgesic, Cough medicine and Antidiarrhoeal properties. It is by far the most widely used opiate in the world and probably the most commonly used drug overall according to numerous reports over the years by organizations such as the World Health Organization and its League of Nations...
 mixed with acetaminophen or ibuprofen
Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug originally marketed as Brufen, and since then under various other trademarks , most notably Nurofen, Advil and Motrin....
 to enhance the action of codeine as a pain reliever. This is often seen with recreational drugs, where 5-HTP, a serotonin precursor often used as an antidepressant, is often used prior to, during, and shortly after recreational use of MDMA as it allegedly increases the "high" and decreases the "comedown" stages of MDMA use (although most anecdotal evidence has pointed to 5-HTP moderately muting the effect of MDMA). Other examples include the use of cannabis
Cannabis

Cannabis is a genus of flowering plants that includes three putative species, Cannabis sativa L., Cannabis indica Lam., and Cannabis ruderalis Janisch....
 with LSD
LSD

Lysergic acid diethylamide, LSD, LSD-25, or acid, is a semisynthetic psychedelic drug of the ergoline family. Its unusual psychological effects, which include visuals of colored patterns behind the eyes in the mind, a sense of time distorting, and crawling geometric patterns, have made it one of the most widely known psyched...
, where the active chemicals in cannabis enhance the hallucinatory experience of LSD-use.

Negative effects of synergy are a form of contraindication
Contraindication

In medicine, a contraindication is a condition or factor that increases the risks involved in using a particular medication, carrying out a medical procedure, or engaging in a particular activity....
, which for instance can be if more than one depressant drug is used that affects the central nervous system
Central nervous system

The central nervous system is the part of the nervous system that functions to coordinate the activity of all parts of the bodies of multicellular organisms....
 (CNS), an example being alcohol
Alcohol

In chemistry, an alcohol is any organic compound in which a hydroxyl Functional group is bound to a carbon atom of an alkyl or substituted alkyl group....
 and Valium. The combination can cause a greater reaction than simply the sum of the individual effects of each drug if they were used separately. In this particular case, the most serious consequence of drug synergy is exaggerated respiratory depression, which can be fatal if left untreated.

Pest synergy

Pest synergy would occur in a biological
Biology

Biology is a branch of the natural sciences concerned with the study of living organisms and their interaction with each other and their environment ....
 host
Host (biology)

In biology, a host is an organism that harbors a virus or parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter....
 organism
Organism

In biology, an organism is any life thing . In at least some form, all organisms are capable of response to stimulus , reproduction, growth and developmental biology, and maintenance of homeostasis as a stable whole....
 population where, for example, the introduction of parasite A may cause 10% fatalities, and parasite B may also cause 10% loss. When both parasites are present, the losses would normally be expected to total less than 20%, yet in some cases, losses are significantly greater. In such cases it is said that the parasites in combination have a synergistic effect.

Positive synergy

Toxicologic synergy is of concern to the public and regulatory agencies because chemicals individually considered safe might pose unacceptable health or ecological risk when exposure is to a combination. Articles in scientific and lay journals include many definitions of chemical or toxicologic synergy, often vague or in conflict with each other. Because toxic interactions are defined relative to the expectation under "no interaction," a determination of synergy (or antagonism) depends on what is meant by "no interaction." The United States Environmental Protection Agency
United States Environmental Protection Agency

The U.S. Environmental Protection Agency is an List of United States federal agencies of the federal government of the United States charged to Regulation of chemicals and protect human health by safeguarding the natural environment: air, water, and land....
 has one of the more detailed and precise definitions of toxic interaction, designed to facilitate risk assessment. In their guidance documents, the no-interaction default assumption is dose addition, so synergy means a mixture response that exceeds that predicted from dose addition. The EPA emphasizes that synergy does not always make a mixture dangerous, nor does antagonism always make the mixture safe; each depends on the predicted risk under dose addition.

For example, a consequence of pesticide use is the risk of health effects. During the registration of pesticide
Pesticide

A pesticide is a substance or mixture of substances used to kill a pest .A pesticide may be a chemical substance, biological agent , antimicrobial, disinfectant or device used against any pest ....
s in the US
United States

The United States of America is a Federal government constitutional republic comprising U.S. state and a federal district. The country is situated mostly in central North America, where its Contiguous United States and Washington, D.C., the Capital districts and territories, lie between the Pacific Ocean and Atlantic Oceans, Borders of the U...
 exhaustive tests are performed to discern health effects on humans at various exposure levels. A regulatory upper limit of presence in foods is then placed on this pesticide. As long as residues in the food stay below this regulatory level, health effects are deemed highly unlikely and the food is considered safe to consume.

However in normal agal practice it is rare to use only a single pesticide. During the production of a crop several different materials may be used. Each of them has had determined a regulatory level at which they would be considered individually safe. In many cases, a commercial pesticide is itself a combination of several chemical agents, and thus the safe levels actually represent levels of the mixture. In contrast, combinations created by the end user, such as a farmer, are rarely tested as that combination. The potential for synergy is then unknown or estimated from data on similar combinations. This lack of information also applies to many of the chemical combinations to which humans are exposed, including residues in food, indoor air contaminants, and occupational exposures to chemicals. Some groups think that the rising rates of cancer, asthma and other health problems may be caused by these combination exposures; others have other explanations. This question will likely be answered only after years of exposure by the population in general and research on chemical toxicity, usually performed on animals.

Human synergy

Human synergy relates to interacting humans. For example, say person A alone is too short to reach an apple
APPLE

This article is about the satellite APPLE. For the fruit apple, see Apple. For other uses see Apple .The Ariane Passenger PayLoad Experiment , was an experimental communication satellite with a C-Band transponder launched by Indian Space Research Organisation satellite on June 19, 1981 by Ariane 1, a launch vehicle of the European Spac...
 on a tree
TREE

TREE was a Boston hardcore punk band formed in the summer of 1990. They were active in the Boston music scene until disbanding in 2002....
 and person B is too short as well. Once person B sits on the shoulder
Shoulder

In human anatomy, the shoulder joint comprises the part of the body where the humerus attaches to the scapula. The shoulder refers to the group of structures in the region of the joint....
s of person A, they are more than tall enough to reach the apple. In this example, the product of their synergy would be one apple. Another case would be two politician
Politician

A politician is an individual who is involved in influencing public decision making through the influence of politics or a person who influences the way a society is governed....
s. If each is able to gather one million votes on their own, but together they were able to appeal to 2.5 million voters, their synergy would have produced 500,000 more votes than had they each worked independently. A song
Song

A song is a musical musical composition which contains vocal parts that are performed, 'sung,' and feature words , commonly accompanied by musical instruments ....
 is also a good example of human synergy, taking more than one musical part and putting them together to create a song that has a much more dramatic effect than each of the parts when played individually.

A third form of human synergy is when one person is able to complete two separate tasks by doing one action. For example, if a person was asked by a teacher
Teacher

In education, a teacher is a person who teaches. A teacher who teaches an individual student may also be described as a personal tutor.The role of teacher is often formal and ongoing, carried out by way of Occupation or Profession at a school or other place of formal education....
 and his boss
Boss

A boss is an employee's supervisor.Boss may also refer to:...
 at work to write an essay
Essay

An essay is usually a short piece of writing. It is often written from an author's personal Perspective . Essays can be literary criticism, political manifestos, learned arguments, observations of daily life, recollections, and reflections of the author....
 on how he could improve his work, that would be considered synergy. Or, a more visual example of this synergy is a drummer
Drummer

A drummer is a musician who plays a drum or drums, particularly a drum kit , marching percussion or hand drums. The term percussionist applies to a musician performing on any percussion instrument, but usually refers to one who plays Classical music or Latin percussion....
 while he's drumming, using four separate rhythm
Rhythm

Rhythm is the variation of the length and accentuation of a series of sounds or other events....
s to create one drum
Drum

The drum is a member of the percussion instrument group, technically classified as a membranophone.. Drums consist of at least one membrane, called a drumhead or drum skin, that is stretched over a shell and struck, either directly with parts of a player's body, or with some sort of implement such as a drumstick, to produce sound....
 beat.

Synergy usually arises when two persons with different complementary skills cooperate. The fundamental example is cooperation of men
MEN

The abbreviation MEN can refer to:* Multiple endocrine neoplasia* Manchester Evening News* Manchester Evening News Arena* Ministry of National Education of the Republic of Poland - Ministerstwo Edukaji Narodowej...
 and women in a couple. In business, cooperation of people with organizational and technical skills happens very often. In general, the most common reason why people cooperate is it brings a synergy. On the other hand, people tend to specialize just to be able to form groups with high synergy (see also division of labor and teamwork
Teamwork

Teamwork "a joint action by 2 or more people' or a group, in which each person subordinates his or her individual interests and opinions to the unity and efficiency of the group."...
).

Corporate synergy

Corporate synergy occurs when corporations interact congruently. A corporate synergy refers to a financial benefit that a corporation expects to realize when it merges with or acquires another corporation. This type of synergy is a nearly ubiquitous feature of a corporate acquisition and is a negotiating point between the buyer and seller that impacts the final price both parties agree to. There are two distinct types of corporate synergies:

Revenue
A revenue synergy refers to the opportunity of a combined corporate entity to generate more revenue than its two predecessor stand alone companies would be able to generate. For example, if company A sells product X through its sales force, company B sells product Y, and company A decides to buy company B then the new company could use each sales person to sell products X and Y thereby increasing the revenue that each sales person generates for the company.

Management
Synergy in terms of management and in relation to team working, refers to the combined effort of individuals as participants of the team. Positive or negative synergy can exist. An easy way to interpret and understand both positive and negative synergy is:

Positive: 2 + 2 = 5, Negative: 2 + 2 = 3

An example of positive synergy is the effects of 'social facilitation', whereas the opposite to this would be 'social loafing'.

Cost
A cost synergy refers to the opportunity of a combined corporate entity to reduce or eliminate expenses associated with running a business. Cost synergies are realized by eliminating positions that are viewed as duplicate within the merged entity. Examples include the head quarters office of one of the predecessor companies, certain executives, the human resources department, or other employees of the predecessor companies. This is related to the economic concept of Economies of Scale
Returns to scale

In economics, returns to scale and economies of scale are related terms that describe what happens as the scale of production increases. They are different terms and should not be used interchangeably....
.

Computers

Synergy can also be defined as the combination of human strengths and computer strengths. Computers can process data much more quickly than humans, but lack the ability to respond to arbitrary stimuli.

Synergy in the media


In media economics, synergy is the promotion and sale of a product (and all its versions) throughout the various subsidiaries of a media conglomerate, e.g. films, soundtracks or video games. Walt Disney
Walt Disney

Walter Elias Disney was a multiple Academy Award-winning American film producer, film director, screenwriter, voice actor, animator, entrepreneur and philanthropist....
 pioneered synergistic marketing techniques in the 1930s by granting dozens of firms the right to use his Mickey Mouse
Mickey Mouse

Mickey Mouse is a funny animal cartoon character who has become an icon for The Walt Disney Company. Mickey Mouse was created in 1928 by Walt Disney and Ub Iwerks and voiced by Walt Disney....
 character in products and ads, and continued to market Disney media through licensing arrangements. These products can help advertise the film itself and thus help to increase the film's sales. For example, the Spider-Man films had toys of webshooters and figures of the characters made, as well as posters and games.

See also

  • Synergetics
    Synergetics

    Synergetics is an interdisciplinary science explaining the formation and self-organization of patterns and structures in open system far from thermodynamic equilibrium....
  • Synergism
    Synergism

    Synergism, in general, may be defined as two or more agents working together to produce a result not obtainable by any of the agents independently....
  • Holism
    Holism

    Holism is the idea that all the properties of a given system cannot be determined or explained by its component parts alone. Instead, the system as a whole determines in an important way how the parts behave....
  • Emergence
    Emergence

    In philosophy, systems theory and science, emergence is the way complex systems and patterns arise out of a Multiplicity of relatively simple interactions....
  • Perfect storm
    Perfect storm

    The phrase perfect storm originates from the 1997 book The Perfect Storm which refers to the simultaneous occurrence of weather events which, taken individually, would be far less powerful than the storm resulting of their chance combination....
  • Systems theory
    Systems theory

    Systems theory is an interdisciplinary field of science and the study of the nature of complex systems in nature, society, and science. More specifically, it is a framework by which one can analyze and/or describe any group of objects that work in concert to produce some result....
  • Synergy - software - synergy.sourceforge.net = "OpenGL 2D/3D(limited) engine based on ZEngine(zengine.sf.net). Goals are to clean it up, add a nice texture manager, basic 3d model support, and several other tweaks. It will reamin a 2D library, the only 3d element will be models."
  • Synergy2 - software - synergy2.sourceforge.net = "Synergy lets you easily share a single mouse and keyboard between multiple computers with different operating systems, each with its own display, without special hardware."


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