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Strabismus

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Strabismus



 
 
Strabismus (from Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
: st?aß?sµ?? strabismos "to squint," from st?aß?? strabos "squinting") is a condition in which the eye
Eye

Eyes are Organ that detect light, and send signals along the optic nerve to the visual system and other areas of the brain. Complex optical systems with resolving power have come in ten fundamentally different forms, and 96% of animal species possess a complex optical system....
s are not properly aligned with each other. It typically involves a lack of coordination between the extraocular muscle
Muscles of orbit

There are six Orbital Muscles; Four of the muscles control the movement of the eye going up and down and side to side. Two of the muscles control the eye to move while the head moves....
s that prevents bringing the gaze of each eye to the same point in space and preventing proper binocular vision
Binocular vision

Binocular vision is Visual perception in which both eyes are used together. The word binocular comes from two Latin roots, bini for double, and oculus for eye....
, which may adversely affect depth perception
Depth perception

Depth perception is the visual perception ability to perceive the world in three dimensions. Although any animal capable of moving around its environment must be able to sense the distance of objects in that environment, the term perception is reserved for humans, who are the only beings that can tell each other about their qualia of dist...
. Strabismus can be either a disorder of the brain coordinating the eyes or a disorder of one or more muscles, as in any process that causes a dysfunction of the usual direction and power of the muscle or muscles.

ng eye examination
Eye examination

An eye examination is a battery of tests performed by an optometrist or ophthalmologist assessing Visual perception and ability to Focus on and discern objects, as well as other tests and examinations pertaining to the eyes....
s, ophthalmologists, orthoptists, and optometrists typically use a cover test
Cover test

A cover test is an objective determination of the presence and amount of ocular deviation. It is typically performed by orthoptists, ophthalmologists and optometrists during eye examinations....
 to aid in the diagnosis of strabismus.






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Strabismus (from Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
: st?aß?sµ?? strabismos "to squint," from st?aß?? strabos "squinting") is a condition in which the eye
Eye

Eyes are Organ that detect light, and send signals along the optic nerve to the visual system and other areas of the brain. Complex optical systems with resolving power have come in ten fundamentally different forms, and 96% of animal species possess a complex optical system....
s are not properly aligned with each other. It typically involves a lack of coordination between the extraocular muscle
Muscles of orbit

There are six Orbital Muscles; Four of the muscles control the movement of the eye going up and down and side to side. Two of the muscles control the eye to move while the head moves....
s that prevents bringing the gaze of each eye to the same point in space and preventing proper binocular vision
Binocular vision

Binocular vision is Visual perception in which both eyes are used together. The word binocular comes from two Latin roots, bini for double, and oculus for eye....
, which may adversely affect depth perception
Depth perception

Depth perception is the visual perception ability to perceive the world in three dimensions. Although any animal capable of moving around its environment must be able to sense the distance of objects in that environment, the term perception is reserved for humans, who are the only beings that can tell each other about their qualia of dist...
. Strabismus can be either a disorder of the brain coordinating the eyes or a disorder of one or more muscles, as in any process that causes a dysfunction of the usual direction and power of the muscle or muscles.

Diagnosis

During eye examination
Eye examination

An eye examination is a battery of tests performed by an optometrist or ophthalmologist assessing Visual perception and ability to Focus on and discern objects, as well as other tests and examinations pertaining to the eyes....
s, ophthalmologists, orthoptists, and optometrists typically use a cover test
Cover test

A cover test is an objective determination of the presence and amount of ocular deviation. It is typically performed by orthoptists, ophthalmologists and optometrists during eye examinations....
 to aid in the diagnosis of strabismus. If the eye being tested is the strabismic eye, then it will fixate on the object after the "straight" eye is covered, as long as the vision in this eye is good enough. If the "straight" eye is being tested, there will be no change in fixation, as it is already fixated. Depending on the direction that the strabismic eye deviates, the direction of deviation may be assessed. Exotropic
Exotropia

Exotropia is a form of strabismus where the eyes are deviated outward. It is the opposite of esotropia. People with exotropia often experience crossed diplopia....
 is outwards (away from the midline) and esotropic
Esotropia

Esotropia is a form of strabismus, or "squint", in which one or both eyes turns inward. The condition can be constantly present, or occur intermittently, and can give the affected individual a "cross-eyed" appearance....
 is inwards (towards the nose).

A simple screening test for strabismus is the Hirschberg test
Hirschberg test

In the fields of optometry and ophthalmology, the Hirschberg test, also Hirschberg corneal reflex test, is a screening test that can be used to assess whether a person has strabismus ....
. A flashlight is shone in the patient's eye. When the patient is looking at the light, a reflection can be seen on the front surface of the pupil. If the eyes are properly aligned with one another, then the reflection will be in the same spot of each eye. Therefore, if the reflection is not in the same place in each eye, then the eyes must not be properly aligned.

Laterality

Strabismus may be classified as unilateral if the same eye consistently 'wanders', or alternating if either of the eyes can be seen to 'wander'. Alternation of the strabismus may occur spontaneously, with or without subjective awareness of the alternation. Alternation may also be seen following the cover test, with the previously 'wandering' eye remaining straight while the previously straight eye is now seen to be 'wandering' on removal of the cover. The cover-uncover test is used to diagnose the type of strabismus (also known as tropia) present.

Onset

Strabismus may also be classified based on time of onset, either congenital, acquired or secondary to another pathological process, such as cataract.

Treatment and management

As with other binocular vision disorders, the primary therapeutic goal for those with strabismus is comfortable, single, clear, normal binocular vision at all distances and directions of gaze.

Whereas amblyopia
Amblyopia

Amblyopia, otherwise known as lazy eye, is a Disease of the visual system that is characterized by poor or indistinct Visual perception in an eye that is otherwise physically normal, or out of proportion to associated structural abnormalities....
, if minor and detected early, can often be corrected with use of an eyepatch
Eyepatch

An eyepatch is a small patch that is worn in front of one eye. It may be a cloth patch attached around the head by an elastic band or by a string, or an adhesive bandage....
 on the dominant eye and/or vision therapy
Vision therapy

Vision therapy, also known as visual training, vision training, or visual therapy, is a group of techniques attempting variously to correct or improve presumed ocular, oculomotor, visual processing, and perceptual disorders." Vision therapy encompasses a wide variety of non-surgical methods which some have divided into two...
, the use of eyepatches is unlikely to change the angle of strabismus. Advanced strabismus is usually treated with a combination of eyeglasses or prism
Prism (optics)

In optics, a prism is a transparent optical element with flat, polished surfaces that refraction light. The exact angles between the surfaces depend on the application....
s, vision therapy, and surgery
Eye surgery

Eye surgery, also known as orogolomistician surgery or ocular surgery, is surgery performed on the eye or its adnexa, typically by an ophthalmologist....
, depending on the underlying reason for the misalignment. Surgery attempts to align the eyes by shortening, lengthening, or changing the position of one or more of the extraocular eye muscles and is frequently the only way to achieve cosmetic improvement. Glasses affect the position by changing the person's reaction to focusing. Prisms change the way light
Light

Light, or visible light, is electromagnetic radiation of a wavelength that is Visible spectrum to the human eye , or up to 380?750 nm. In the broader field of physics, light is sometimes used to refer to electromagnetic radiation of all wavelengths, whether visible or not....
, and therefore images, strike the eye, simulating a change in the eye position.

Early treatment of strabismus and/or amblyopia in infancy can reduce the chance of developing amblyopia and depth perception problems. Eyes that remain misaligned can still develop visual problems. Although not a cure for strabismus, prism lenses
Lens (optics)

A lens is an optics device with perfect or approximate axial symmetry which transmittance and refraction light, converging or diverging the beam....
 can also be used to provide some comfort for sufferers and to prevent double vision from occurring.

In adult
Adult

The term adult has at least three distinct meanings. It can indicate a biologically grown or mature person. It may also mean a plant, animal, or person who has reached full growth or alternatively is capable of reproduction, or a person who has attained the legally fixed age of majority; as opposed to a minor....
s with previously normal alignment, the onset of strabismus usually results in double vision (diplopia
Diplopia

Diplopia, commonly known as double vision, is the simultaneous perception of two images of a single object. These images may be displaced horizontally, vertically, or diagonally in relation to each other....
).

Prognosis

When strabismus is congenital or develops in infancy, it can cause amblyopia
Amblyopia

Amblyopia, otherwise known as lazy eye, is a Disease of the visual system that is characterized by poor or indistinct Visual perception in an eye that is otherwise physically normal, or out of proportion to associated structural abnormalities....
, in which the brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
 ignores input from the deviated eye. Strabismus can lead to a permanent weakening of vision in the strabismic eye called amblyopia
Amblyopia

Amblyopia, otherwise known as lazy eye, is a Disease of the visual system that is characterized by poor or indistinct Visual perception in an eye that is otherwise physically normal, or out of proportion to associated structural abnormalities....
 (this may not always happen), sometimes referred to as lazy eye
Amblyopia

Amblyopia, otherwise known as lazy eye, is a Disease of the visual system that is characterized by poor or indistinct Visual perception in an eye that is otherwise physically normal, or out of proportion to associated structural abnormalities....
. The appearance of strabismus may also be a cosmetic
Beauty

Beauty is a characteristic of a person, Location , Object , or idea that provides a perception experience of pleasure, Value , or satisfaction....
 problem. One study reported that 85% of adult strabismus patients "reported that they had problems with work, school
School

File:Primary Student of Pakistan.JPGA school , is an institution designed to allow and encourage students to education, under the supervision of teachers....
 and sport
Sport

Sport is an activity that is governed by a set of regulation of sport or traditions and often engaged in competitively. Sports commonly refer to activities where the physical capabilities of the competitor are the sole or primary determinant of the outcome , but the term is also used to include activities such as mind sports and motor...
s because of their strabismus." The same study also reported that 70% said strabismus "had a negative effect on their self-image."

Differential diagnosis: pseudostrabismus

Pseudostrabismus
Pseudostrabismus

Pseudostrabismus is the false appearance of crossed eyes. When the eyes are actually crossed or not completely aligned with one another it is called strabismus....
 is the false appearance of strabismus. It generally occurs in infants and toddlers whose bridge of the nose is wide and flat, causing the appearance of strabismus. With age, the bridge of the child's nose narrows and the folds in the corner of the eyes go away. To detect the difference between pseudostrabismus and strabismus, a Hirschberg test
Hirschberg test

In the fields of optometry and ophthalmology, the Hirschberg test, also Hirschberg corneal reflex test, is a screening test that can be used to assess whether a person has strabismus ....
 may be used.

Pathophysiology


Strabismus can be an indication that a cranial nerve has a lesion. Particularly Cranial Nerve III (Occulomotor)
Oculomotor nerve

The oculomotor nerve is the third of twelve paired cranial nerves. It controls most of the eye's movements, constriction of the pupil, and maintains an open eyelid....
, Cranial Nerve IV (Trochlear)
Trochlear nerve

The trochlear nerve is a motor nerve that innervates a single muscle: the superior oblique muscle of the eye. An older name is pathetic nerve, which refers to the dejected appearance that is characteristic of patients with fourth nerve palsies....
 or Cranial Nerve VI (Abducens). A strabismus caused by a lesion in either of these nerves results in the lack of innervation to eye muscles and results in a change of eye position. A strabismus may be a sign of increased intracranial pressure, as CN III is particularly vulnerable to damage from brain swelling.

More commonly however, squints are termed concominant (i.e. non paralytic). This means the squint is not caused by a lesion reducing innervation. The squint in this example, is caused by a refractive error in one or both eyes. This refractive error causes poor vision in one eye and so stops the brain from being able to use both eyes together.

Other terms

Strabismus is often incorrectly referred to as "lazy eye" (which in fact refers to the associated condition amblyopia
Amblyopia

Amblyopia, otherwise known as lazy eye, is a Disease of the visual system that is characterized by poor or indistinct Visual perception in an eye that is otherwise physically normal, or out of proportion to associated structural abnormalities....
). It is also referred to as "squint", "crossed eye", "codeye" and "wall eye".

"Cross-eyed" or "boss-eyed" means that when a person with strabismus looks at an object, one eye fixates the object and the other fixates with a convergence angle less than zero, that is the optic axes overconverge. "Wall-eyed" means that when a person with strabismus looks at an object, one eye fixates the object and the other fixates with a convergence angle greater than zero, that is the optic axes diverge from parallel
Parallel

From Greek language: pa???????? Parallel may refer to:...
.

See also

  • Duane syndrome
    Duane syndrome

    Duane syndrome is a rare, congenital eye movement disease most commonly characterized by the inability of the eye to turn out. The syndrome was first described by Jakob Stilling and Siegmund T?rk , and subsequently named for Alexander Duane who discussed the disorder in more detail in 1905...
  • List of people with strabismus
    List of people with strabismus

    This is a list of people who have, or had but corrected, the medical condition strabismus:* Abraham Lincoln, lawyer, politician, and the sixteenth President of the United States;...
  • Möbius syndrome
  • Orthoptics
  • Pediatric ophthalmology
    Pediatric ophthalmology

    Pediatric ophthalmology is a sub-speciality of ophthalmology concerned with eye diseases, visual development, and vision care in children....
  • Retinoblastoma
    Retinoblastoma

    Retinoblastoma is a rapidly developing cancer which develops in the cells of the retina, the light sensitive cells of the eye. In the developed world, Rb has one of the best cure rates of all childhood cancers , with more than nine out of every ten sufferers surviving into adulthood....
  • Sixth (abducent) nerve palsy
  • Strabismus surgery
    Strabismus surgery

    Strabismus surgery is surgery on the extraocular muscles to correct the misalignment of the eyes. With approximately 1.2 million procedures each year, extraocular muscle surgery is the third most common eye surgery in the United States....


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