Schlosser's base
Encyclopedia
Schlosser's base describes various superbasic
mixtures of an alkyllithium compound and a potassium alkoxide. Commonly, the mixture is composed of n-butyllithium
and potassium tert-butoxide
. The reagent is named after Manfred Schlosser, though he uses the term LICKOR superbase (LIC denoting the alkyllithium, and KOR denoting the potassium alkoxide).
Superbase
In chemistry, a superbase is an extremely strong base, that is a compound that has a high affinity for protons. Hydroxide ion is the strongest base possible in aqueous solutions, but bases exist with pKb's well outside of the aqueous range. Such bases are valuable in organic synthesis and are...
mixtures of an alkyllithium compound and a potassium alkoxide. Commonly, the mixture is composed of n-butyllithium
N-Butyllithium
n-Butyllithium is an organolithium reagent. It is widely used as a polymerization initiator in the production of elastomers such as polybutadiene or styrene-butadiene-styrene...
and potassium tert-butoxide
Potassium tert-butoxide
Potassium tert-butoxide is the chemical compound with the formula 3COK. This colourless solid is a strong base useful in organic synthesis. It exists as a tetrameric cubane-like cluster...
. The reagent is named after Manfred Schlosser, though he uses the term LICKOR superbase (LIC denoting the alkyllithium, and KOR denoting the potassium alkoxide).