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Scar

 
Scar

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Scar



 
 
Scars (also called cicatrices) are areas of fibrous tissue
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
 that replace normal skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
 (or other tissue) after injury. A scar results from the biologic process of wound
Wound

In medicine, a wound is a type of injury in which the skin is torn, cut or punctured , or where blunt force physical trauma causes a bruise . In pathology, it specifically refers to a sharp injury which damages the dermis of the skin....
 repair in the skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
 and other tissues
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
 of the body. Thus, scarring is a natural part of the healing
Healing

Healing, assessed physically, is the process by which the Cell in the body regenerate and repair to reduce the size of a damaged or necrosis area.Healing incorporates both the removal of necrotic Biological tissue , and the replacement of this tissue....
 process. With the exception of very minor lesions, every wound (e.g. after accident
Accident

An accident is a specific, identifiable, unexpected, unusual and unintended external action which occurs in a particular time and place, without apparent or deliberate cause but with marked effects....
, disease
Disease

A disease or medical condition is an abnormal condition of an organism that impairs bodily functions, associated with specific symptoms and Medical signs....
, or surgery
Surgery

Surgery is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, to help improve bodily function or appearance, or sometimes for some other reason....
) results in some degree of scarring.

Scar tissue is not identical to the tissue that it replaces and is usually of inferior functional quality.






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Scars (also called cicatrices) are areas of fibrous tissue
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
 that replace normal skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
 (or other tissue) after injury. A scar results from the biologic process of wound
Wound

In medicine, a wound is a type of injury in which the skin is torn, cut or punctured , or where blunt force physical trauma causes a bruise . In pathology, it specifically refers to a sharp injury which damages the dermis of the skin....
 repair in the skin
Skin

The skin is the outer covering of the body, also known as the epidermis. It is the largest organ of the integumentary system made up of multiple layers of epithelial biological tissue, and guards the underlying muscles, bones, ligaments and organ s....
 and other tissues
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
 of the body. Thus, scarring is a natural part of the healing
Healing

Healing, assessed physically, is the process by which the Cell in the body regenerate and repair to reduce the size of a damaged or necrosis area.Healing incorporates both the removal of necrotic Biological tissue , and the replacement of this tissue....
 process. With the exception of very minor lesions, every wound (e.g. after accident
Accident

An accident is a specific, identifiable, unexpected, unusual and unintended external action which occurs in a particular time and place, without apparent or deliberate cause but with marked effects....
, disease
Disease

A disease or medical condition is an abnormal condition of an organism that impairs bodily functions, associated with specific symptoms and Medical signs....
, or surgery
Surgery

Surgery is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, to help improve bodily function or appearance, or sometimes for some other reason....
) results in some degree of scarring.

Scar tissue is not identical to the tissue that it replaces and is usually of inferior functional quality. For example, scars in the skin are less resistant to ultraviolet radiation, and sweat gland
Sweat gland

The skin contains two different groups of sweat glands: apocrine sweat glands and merocrine sweat glands. Both gland types contain myoepithelial cells , specialized epithelial cells located between the gland cells and the underlying basal lamina....
s and hair follicle
Hair follicle

A hair follicle is part of the skin that grows hair by packing old Cell s together. Attached to the follicle is a sebaceous gland, a tiny sebum-producing gland found everywhere except on the hands, lips and soles of the feet....
s do not grow back within scar tissue. A myocardial infarction
Myocardial infarction

Myocardial infarction , commonly known as a heart attack, occurs when the Blood flow to part of the heart is interrupted. This is most commonly due to occlusion of a coronary artery following the rupture of a Vulnerable plaque, which is an unstable collection of lipids and white blood cells in the wall of an artery....
, commonly known as a heart attack, causes scar formation in the heart
Heart

The heart is a muscle organ in all vertebrates responsible for pumping blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in annelids, mollusks, and arthropods....
 muscle, which leads to loss of muscular power and possibly heart failure. However, there are some tissues (e.g. bone
Bone

Bones are rigid organ that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red blood cell and white blood cells and store minerals....
) that can heal without any structural or functional deterioration.

The word scar was derived from the Greek word eschara, meaning place of fire (fireplace).

How scarring occurs


A scar is a natural part of the healing process. Skin scars occur when the deep, thick layer of skin (the dermis
Dermis

File:EpidermisPainted.svgThe dermis is a layer of skin between the epidermis_ and subcutaneous tissues, and is composed of two layers, the papillary_dermis and reticular dermis....
) is damaged. The worse the damage is, the worse the scar will be.

Most skin scars are flat, pale and leave a trace of the original injury
Injury

Injury or bodily injury is damage or harm caused to the structure or Purpose of the body caused by an outside wiktionary:agent or force, which may be physical or chemical....
 that caused them. The redness that often follows an injury to the skin is not a scar, and is generally not permanent. The time it takes for it to go away may, however, range from a few days to, in some serious and rare cases, a few years. Various treatments can speed up the process in serious cases.

Scars form differently based on the location of the injury on the body and the age of the person who was injured.

To mend the damage, the body has to lay down new collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
 fibres (a naturally occurring protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
 that is produced by the body). Recent research has implicated the gene osteopontin
Osteopontin

Secreted phosphoprotein 1 , also known as bone sialoprotein I , early T-lymphocyte activation , and most commonly as osteopontin , is a human gene product, which is also conserved in other species....
 in scarring and developed a gel that inhibits the process .

This process results in a fortuna scar. Because the body cannot re-build the tissue exactly as it was, the new scar tissue will have a different texture and quality than the surrounding normal tissue. An injury does not become a scar until the wound has completely healed.

Transforming Growth Factors (TGF) play a critical role in scar development and current research is investigating the manipulation of these TGFs for drug development to prevent scarring from the emergency adult wound healing process. As well, a recent American study implicated the protein Ribosomal s6 kinase
Ribosomal s6 kinase

In molecular biology, ribosomal s6 kinase is a family of protein kinases involved in signal transduction. There are two subfamilies of rsk, p90rsk, also known as MAPK-activated protein kinase-1 , and p70rsk, also known as S6-H1 Kinase or simply S6 Kinase....
 (RSK) in the formation of scar tissue and found that the introduction of a chemical to counteract RSK could halt the formation of Cirrhosis
Cirrhosis

Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver Tissue by fibrous scar tissue as well as regenerative Nodule , leading to progressive loss of liver function....
. This treatment also has the potential to reduce or even prevent altogether other types of scarring.

Abnormal scars

Two types of scars are the result of the body overproducing collagen, which causes the scar to be raised above the surrounding skin. Hypertrophic scars take the form of a red raised lump on the skin, but do not grow beyond the boundaries of the original wound, and they often improve in appearance after a few years. Keloid
Keloid

A keloid is a type of hypertrophic scar with mainly type I and some type III collagen which results in an overgrowth of tissue at the site of a healed skin injury....
 scars are a more serious form of scarring, because they can carry on growing indefinitely into a large, tumorous (although benign) growth.

Keloid scars can occur on anyone, but they are most common in dark-skinned people. Keloid scars can be caused by surgery, an accident, by acne
Acne vulgaris

Acne vulgaris is a skin condition caused by changes in the pilosebaceous units . Severe acne is inflammation, but acne can also manifest in noninflammatory forms....
 or, sometimes, from body piercings. In some people, keloid scars form spontaneously.

Although they can be a cosmetic problem, keloid scars are only inert masses of collagen and therefore completely harmless and non-contagious. However, they can be itchy or painful in some individuals. They tend to be most common on the shoulder
Shoulder

In human anatomy, the shoulder joint comprises the part of the body where the humerus attaches to the scapula. The shoulder refers to the group of structures in the region of the joint....
s and chest
Chest

The chest is a part of the anatomy of humans and various other animals sometimes referred to as the thorax....
.

Alternately, a scar can take the form of a sunken recess in the skin, which has a pitted appearance. These are caused when underlying structures supporting the skin, such as fat
Fat

Fats consist of a wide group of compounds that are generally soluble in organic solvents and largely insoluble in water. Chemistry, fats are generally ester of glycerol and fatty acids....
 or muscle
MUSCLE

MUSCLE is public domain, multiple sequence alignment software for protein and nucleotide sequences.MUSCLE is integrated into UGENE bioinformatics tool as a plugin....
, are lost. This type of scarring is commonly associated with acne, but can be caused by chickenpox
Chickenpox

Chickenpox or chicken pox is a highly contagious illness caused by primary infection with varicella zoster virus . It generally begins with a vesicular skin rash appearing in two or three waves, mainly on the body and head rather than the hands and becoming itchy raw pockmarks, small open sores which heal mostly without scarring....
, surgery or an accident.

Scars can also take the form of stretched skin
Stretch marks

Stretch marks or striae , as they are called in dermatology, are a form of scarring on the skin with an off-color hue. They are caused by tearing of the dermis, and over time can diminish but not disappear completely....
. These are called striae and are caused when the skin is stretched rapidly (for instance during pregnancy
Pregnancy

Pregnancy is the carrying of one or more offspring, known as a fetus or embryo, inside the uterus of a female. In a pregnancy, there can be multiple gestations, as in the case of twins or Multiple birth....
, significant weight gain or adolescent growth spurts), or when skin is put under tension during the healing process, (usually near joints). This type of scar usually improves in appearance after a few years.

Treatments for skin scars

No scar can ever be completely removed and treatments will always leave a trace, but a number of approaches have been tried with silicon gel sheeting and steroid injections having the most widely accepted role in general scar treatment.

In historical sequence, corticosteroid
Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiology systems such as stress , immune system and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior....
 therapy by injection into the scars was introduced in the 1960s, from the early 1970s pressure garment therapy was introduced for widespread burn scars, and silicone gel sheets from the 1980s.

Topical treatments

Silicone sheeting is considered a non-invasive Class 1 Medical device, and is easier to use and with lower risks of side effects compared to surgical excision, steroid injections, pressure therapy, laser and cryotherapy treatments.Silicone sheeting technology is used by plastic surgeons and burn centers to provide patients with optimal results. In the past, silicone gel sheets were thick and uncomfotable and suceptible to cracking and breakdown, but newer technologies have improved performance.

Needling

Needling is an inexpensive process where the scarred area is continuously needled to promote collagen formation. Once needled the area is allowed to fully heal, and needled again if required depending on the intensity of the scar. Scarring needles and needling rollers are available for home use; however, needling should not be done on parts of the face or areas where major nerves are located without professional medical supervision. Needling at home must also be done in line with hygienic and sterilization requirements.

Pressure garments

Pressure garments should be used only under supervision by a medical professional. They are most often used for burn
Burn (injury)

A burn is a type of injury that may be caused by heat, Temperature, electricity, chemicals, light, radiation, or friction. Burns can be highly variable in terms of the tissue affected, the severity, and resultant complications....
 scars that cover a large area, this treatment is only effective on recent scars.

Pressure garments are usually custom-made from elastic
Elastomer

An elastomer is a polymer with the property of elasticity. The term, which is derived from elastic polymer, is often used interchangeably with the term rubber, and is preferred when referring to vulcanization....
 materials, and fit tightly around the scarring. They work best when they are worn 24 hours a day for six to twelve months.

It is believed that they work by applying constant pressure to surface blood vessels and eventually causing scars to flatten and become softer.

Steroid injections

A long term course of steroid
Steroid

A steroid is a terpenoid lipid characterized by a carbon skeleton with four fused rings, generally arranged in a 6-6-6-5 fashion.Steroids vary by the functional groups attached to these rings and the oxidation state of the rings....
 injections under medical supervision, into the scar may help flatten and soften the appearance of keloid or hypertrophic scars.

The steroid is injected into the scar itself; since very little is absorbed into the blood stream, side effects of this treatment are minor. However, does cause thinning of tissue so does carry risks when injected into scars caused by operations into ruptured tendons. This treatment is repeated at 4-6 week intervals.

Dermabrasion

Dermabrasion
Dermabrasion

Dermabrasion is a beauty medical procedure in which the surface of the epidermis of the skin is removed by Abrasion .It is used to remove sun-damaged skin and to remove or lessen scars and dark spots on the skin....
 involves the removal of the surface of the skin with specialist equipment and usually involves a general anaesthetic
General anaesthetic

A general anaesthetic drug is an anaesthetic drug that brings about a reversible loss of consciousness. These drugs are generally administered by an anesthesia provider in order to induce or maintain general anaesthesia to facilitate surgery....
. It is useful with raised scars, but is less effective when the scar is sunken below the surrounding skin.

Collagen injections

Collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
 injections can be used to raise sunken scars to the level of surrounding skin. Its effects are however temporary, and it needs to be regularly repeated. There is also a risk in some people of an allergic reaction.

Laser surgery & resurfacing

The use of laser
Laser

A laser is a device that emits light through a process called stimulated emission. The term laser is an acronym for light amplification by stimulated emission of radiation....
s on scars is a new form of treatment that is still being improved.

Vascular lasers have been proven to greatly reduce the redness of most scars 6-10 weeks after the initial treatment. They have not been proven effective in flattening scars however. It has been theorized that removing layers of skin with a carbon dioxide
Carbon dioxide laser

The carbon dioxide laser was one of the earliest gas lasers to be developed , and is still one of the most useful. Carbon dioxide lasers are the highest-power continuous wave lasers that are currently available....
 or erbium laser may help flatten scars.

Several cosmetic lasers have been FDA approved for the treatment of acne scars
Acne scar treatment

There are several forms of treatment for acne scars in current usage....
 by using laser resurfacing
Laser resurfacing

Laser resurfacing is a technique used during laser surgery wherein molecular bonds of a material are dissolved by a laser. It is used for the treatment of wrinkles, Lentigo malignas, Sunburn, scars , stretch marks, actinic keratosis and telangiectasias or "spider veins" - a symptom of ataxia telangiectasia....
 techniques.

Surgery

Scars, such as acne scars, can be cut out and stitched up, a process called scar revision - Although this method has been known to result in the new wound healing the same way (as a hypertrophic scar).

Radiotherapy

Low-dose, superficial radiotherapy, is used to prevent re-occurrence of severe keloid and hypertrophic scarring. It is usually effective, but only used in extreme cases due to the risk of long-term side effects.

Natural remedies

Research shows the use of vitamin E and onion extract as a treatment for scars has been proven ineffective, though in some cases it may worsen scar appearance.

Intentional scarring

The permanence of scarring has led to its intentional use as a form of body art
Body art

Body art is art made on, with, or consisting of, the human body. The most common forms of body art are tattoos and body piercings, but other types include scarification, scarification, scalpelling, shaping , body suit and body painting....
 within some cultures and subcultures (see scarification
Scarification

Scarifying involves scratching, etching, or some sort of superficial cutting or incision. Scarification, in botany, involves cutting the seed coat using abrasion, thermal stress, or chemicals to encourage germination....
). These forms of ritual and non ritual scarring practices can be found in many groups and cultures around the world.

See also

  • Dermatology
    Dermatology

    Dermatology is the branch of medicine dealing with the skin and Skin disease, a unique specialty with both medical and surgical aspects. The name of this specialty originated in the form of the words dermologie and, a little later, dermatologia ....
  • Plastic surgery
    Plastic surgery

    Plastic surgery is a medical :Category:Surgical specialties concerned with the correction or restoration of form and function. While famous for aesthetic surgery, plastic surgery also includes a variety of fields such as craniofacial surgery, hand surgery, burn surgery, microsurgery, and reconstructive surgery....
  • Scarification
    Scarification

    Scarifying involves scratching, etching, or some sort of superficial cutting or incision. Scarification, in botany, involves cutting the seed coat using abrasion, thermal stress, or chemicals to encourage germination....
  • Self-injury


External links

  • article
  • "What is a scar?"
  • article
  • : Radiation Therapy for Keloid and Hypertrophic Scar
http://www.reygani.com/page11.html removing scars