SR 59230A
Encyclopedia
SR 59230A is a selective antagonist of the beta-3 adrenergic receptor
Beta-3 adrenergic receptor
The beta-3 adrenergic receptor , also known as ADRB3, is an beta-adrenergic receptor, and also denotes the human gene encoding it.-Function:Actions of the β3 receptor include:*Enhancement of lipolysis in adipose tissue....

, but subsequently shown to also act at α1 adrenoceptors at high doses. It has been shown to block the hyperthermia
Hyperthermia
Hyperthermia is an elevated body temperature due to failed thermoregulation. Hyperthermia occurs when the body produces or absorbs more heat than it can dissipate...

 produced by MDMA in animal studies.
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