Puerarin
Encyclopedia
Puerarin is one of several known isoflavone
Isoflavone
Isoflavones comprise a class of organic compounds, often naturally occurring, related to the isoflavonoids. Many act as phytoestrogens in mammals...

s. Puerarin is found in a number of plants and herbs like the root of Pueraria
Pueraria
Pueraria is a genus of 15–20 species of plants native to Asia.The genus is polyphyletic, with different species being related to species in Glycine , Amphicarpaea, Nogra, Teyleria, Neonotonia, Pseudovigna, Pseudeminia, Pachyrhizus , and other genera of the tribe Phaseoleae.- Species :The...

(Radix puerariae) notably of the kudzu
Kudzu
Kudzu is a plant in the genus Pueraria in the pea family Fabaceae, subfamily Faboideae. It is a climbing, coiling, and trailing vine native to southern Japan and southeast China. Its name comes from the Japanese name for the plant, . It is a weed that climbs over trees or shrubs and grows so...

 plant.

Puerarin is the 8-C-glucoside
Glucoside
A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes....

 of daidzein
Daidzein
Daidzein belongs to the group of isoflavones. Daidzein and other isoflavone compounds, such as genistein, are present in a number of plants and herbs like the Thai Kwao Krua or Pueraria mirifica, Kudzu or Pueraria lobata, and in food sources such as soybeans and soy products like tofu and textured...

.

Puerarin is a 5-HT2C receptor
5-HT2C receptor
The 5-HT2C receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin . It is a G protein-coupled receptor that is coupled to Gq/G11 and mediates excitatory neurotransmission. HTR2C denotes the human gene encoding for the receptor, that in humans is located at the...

 and benzodiazepine site antagonist.

Puerarin is being investigated as a self-microemulsifying drug delivery system
Self-microemulsifying drug delivery system
A self-microemulsifying drug delivery system is a drug delivery system that uses a microemulsion achieved by chemical rather than mechanical means. That is, by an intrinsic property of the drug formulation, rather than by special mixing and handling. It employs the familiar ouzo effect displayed...

.
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