Polyvinyl acetate phthalate
Encyclopedia
Polyvinyl acetate phthalate (PVAP) is a commonly used polymer
phthalate in the formulation of pharmaceuticals, such as the enteric coating
of tablet
s or capsules. It is a vinyl acetate
polymer that is partially hydrolyzed and then esterified with phthalic acid
. Its main use in pharmaceutics is with enteric formulations
and controlled release
formulations.
Polymer
A polymer is a large molecule composed of repeating structural units. These subunits are typically connected by covalent chemical bonds...
phthalate in the formulation of pharmaceuticals, such as the enteric coating
Enteric coating
An enteric coating is a barrier applied to oral medication that controls the location in the digestive system, where it is absorbed. Enteric refers to the small intestine, therefore enteric coatings prevent release of medication before it reaches the small intestine.Most enteric coatings work by...
of tablet
Tablet
A tablet is a pharmaceutical dosage form. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose...
s or capsules. It is a vinyl acetate
Vinyl acetate
Vinyl acetate is an organic compound with the formula CH3COOCH=CH2. A colorless liquid with a pungent odor, it is the precursor to polyvinyl acetate, an important polymer in industry.-Production:...
polymer that is partially hydrolyzed and then esterified with phthalic acid
Phthalic acid
Phthalic acid is an aromatic dicarboxylic acid, with formula C6H42. It is an isomer of isophthalic acid and terephthalic acid. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large...
. Its main use in pharmaceutics is with enteric formulations
Enteric coating
An enteric coating is a barrier applied to oral medication that controls the location in the digestive system, where it is absorbed. Enteric refers to the small intestine, therefore enteric coatings prevent release of medication before it reaches the small intestine.Most enteric coatings work by...
and controlled release
Controlled release
Controlled release is a term referring to the presentation or delivery of compounds in response to stimuli or time. This can be for purposes in several areas including agriculture, cosmetics and personal care, pharmaceuticals and food science. Most commonly it refers to time dependent release in...
formulations.