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Pinworm

 

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Pinworm



 
 
The pinworm (Genus Enterobius), also known as threadworm is a parasitic roundworm of the phylum Nematoda.

Forms of worm
The best known is the human pinworm Enterobius vermicularis and the more recently discovered Enterobius gregorii
Enterobius gregorii

The pinworm Enterobius gregorii is a parasitic roundworm of the phylum Nematoda.In 1983 Jean-Pierre Hugot declared his isolation of a new human parasite....
. The adult pinworm male is 1–4 mm in length, while the adult female is 8–13 mm and possesses the long, pin-shaped posterior for which the worm is named.






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The pinworm (Genus Enterobius), also known as threadworm is a parasitic roundworm of the phylum Nematoda.

Forms of worm


The best known is the human pinworm Enterobius vermicularis and the more recently discovered Enterobius gregorii
Enterobius gregorii

The pinworm Enterobius gregorii is a parasitic roundworm of the phylum Nematoda.In 1983 Jean-Pierre Hugot declared his isolation of a new human parasite....
. The adult pinworm male is 1–4 mm in length, while the adult female is 8–13 mm and possesses the long, pin-shaped posterior for which the worm is named. The human pinworm is commonly found in children, but adults may also be affected.

Habitat

The pinworm lives in the large intestine and cecum. It is found worldwide, and causes the most common infection enterobiasis
Enterobiasis

Enterobiasis is the medical condition of being infection with pinworms . It may be referred to, less precisely, as oxyuriasis, in reference to the Family Oxyuridae, which contains the genus Enterobius....
 in humans. Unlike many other intestinal parasite
Intestinal parasite

Intestinal parasites are parasites that populate the gastro-intestinal tract in humans. They can live throughout the body, but most prefer the intestinal wall....
s, the pinworm does not usually enter the bloodstream or any other organs besides the intestines. Only in rare cases are pinworms found in the vagina
Vagina

The vagina is a fibromuscular cylinder tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles....
, and even more rarely in the uterus
Uterus

The uterus is a major female hormone-responsive reproductive sex organ of most mammals, including humans. It is within the uterus that the fetus develops during gestation....
, fallopian tube
Fallopian tube

The Fallopian tubes, named after Gabriel Fallopius , also known as oviducts, uterine tubes, and salpinges are two very fine tubes lined with cilia epithelia, leading from the ovaries of female mammals into the uterus....
s, liver
Liver

The liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion....
, and peritoneum
Peritoneum

In higher vertebrates, the peritoneum is the serous membrane that forms the lining of the abdomen — it covers most of the intra-abdominal organs....
, but the worms cannot survive long in these places.

The human pinworm Enterobius vermicularis is a ubiquitous parasite of man, it being estimated that over 200 million people are infected annually. It is more common in the temperate regions of Western Europe and North America (its existence is relatively rare in the tropics), and is found particularly in children. Samples of Caucasian children in the U.S.A. and Canada have shown incidences of infection of between 30% to 80%, with similar levels in Europe.

Reproduction

After mating, the male dies. The female migrates to the anus
Anus

The anus is an opening at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as coprolite ; food material after all the nutrients have b...
 and emerges, usually during the night, to deposit about 10,000 to 20,000 egg
Egg (biology)

In most birds and reptiles, an egg is the zygote, resulting from fertilization of the ovum. To enable incubation the egg is usually kept within a favourable temperature range as it nourishes and protects the growing embryo....
s in the perianal area (around the anus). She then secretes a substance which causes a very strong itch
Itch

Itch is an unpleasant sensation that evokes the desire or reflex to scratch. Itch has resisted many attempts to classify it as any one type of sensory experience....
ing sensation, inciting the host to scratch the area and thus transfer some of the eggs to the fingers. Eggs can also be transferred to cloth, toys, and the bathtub. Once ingested orally, the larva
Larva

A larva is a young form of animal with indirect developmental biology, going through or undergoing metamorphosis .The larva can look completely different from the adult form, for example, a caterpillar differs from a butterfly....
e hatch in the small intestine specifically the duodenum and migrate back to the large intestine where they mature; maturity is reached in 30-45 days. The eggs can survive for 2 to 3 weeks on their own outside of the human body. In some cases, the larvae will hatch in the peri-anal area and travel back inside the anus, up the rectum, and back into the intestines where they mature.

Effects

Except for itching pinworm infestation does not usually cause any damage to the body. Sleep disturbance may arise from the itching or crawling sensations. Some case reports suggest that severe infestation may be associated with an increased risk for appendicitis
Appendicitis

Appendicitis is a condition characterized by inflammation of the Vermiform appendix. It is a medical emergency. All cases require removal of the inflamed appendix, either by laparotomy or laparoscopy....
. There is also some evidence of an association between enterobiasis
Enterobiasis

Enterobiasis is the medical condition of being infection with pinworms . It may be referred to, less precisely, as oxyuriasis, in reference to the Family Oxyuridae, which contains the genus Enterobius....
 and diminished zinc levels.

Diagnosis

Diagnosis is often made clinically by observing the female worm (or many worms) in the peri-anal region, but can also be made using the "scotch-tape" test, in which the sticky side of a strip of cellophane
Cellophane

Cellophane is a thin, transparent sheet made of regenerated cellulose. Its low permeability to air, oils and Fats, and bacterium makes it useful for food packaging....
 tape is pressed against the peri-anal skin, then examined under a microscope for pinworm eggs.

The actual worms may be seen in the host's faeces; however the eggs are invisible to the naked eye.

The diagnostic characteristics are: size 50-60 µm by 20-32 µm; typical elongated shape, with one convex side and one flattened side and colorless shell .

On histologic
Histology

Histology is the study of the anatomy of cell and tissue of plants and animals. It is performed by examining a thin slice of tissue under a light microscope or electron microscope....
 cross-section, alae or wings (running the length of the worm) are identifying features of the pinworm (see micrograph).

Treatment

Anti-pinworm drugs such as albendazole
Albendazole

Albendazole, marketed as Albenza, Eskazole, or Zentel, is a member of the benzimidazole compounds used as a medication indicated for the Pharmacotherapy of a variety of worm infestations....
 (Albenza), mebendazole
Mebendazole

Mebendazole or MBZ, marketed as Ovex, Vermox, Antiox, is a benzimidazole drug that is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms....
 (Vermox, OVEX), Piperazine
Piperazine

Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. Piperazine exists as small alkaline deliquescent crystals with a salt taste....
 and pyrantel pamoate
Pyrantel pamoate

Pyrantel pamoate is used as a deworming agent in the treatment of hookworms and roundworms in domesticated animals such as horses, cattle, sheep, pigs, cats, dogs, and many other species....
 (Pin-X, Reese's Pinworm Medication) are commonly used to treat pinworms as well as ascaris lumbricoides
Ascaris lumbricoides

Ascaris lumbricoides is the member of the Ascaris family responsible for the disease Ascariasis.It can reach a length of up to 35 cm....
 (the roundworm). It is not a necessity to visit a doctor to get these drugs, as pyrantel pamoate (Pin-X) is available as an over-the-counter medication (albendazole and mebendazole are prescription in the US); ask a pharmacist for medicines to treat pinworms (or threadworms as they are known in the UK). These medicines kill the pinworms 95% of the time, but do not kill the eggs. The person being treated may have to return after a time of two weeks to be re-treated. Another precaution is to wash the hands before eating (to prevent any pinworm eggs under fingernails from being ingested) and to wash any area or clothes which have touched or been in the vicinity of the infected areas. Treating the entire family is often necessary for cure.

Additional images


See also

  • List of parasites (human)
    List of parasites (human)

    EndoparasitesProtozoan organismsHelminths organisms Other organismsEctoparasites...
  • Enterobius gregorii
    Enterobius gregorii

    The pinworm Enterobius gregorii is a parasitic roundworm of the phylum Nematoda.In 1983 Jean-Pierre Hugot declared his isolation of a new human parasite....


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