PTK2B
Encyclopedia
Protein tyrosine kinase 2 beta is an enzyme
that in humans is encoded by the PTK2B gene
.
with PTPN11
, PTPN6
, PITPNM1
, Gelsolin
, Src
, GRIN2A
, Ewing sarcoma breakpoint region 1
, RB1CC1
, TGFB1I1
, NPHP1
, BCAR1
, FYN
, DLG4
, DLG3
, DDEF2
, Cbl gene
, RAS p21 protein activator 1
, Paxillin
and SORBS2
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the PTK2B gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Protein
Interactions
PTK2B has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with PTPN11
PTPN11
Tyrosine-protein phosphatase non-receptor type 11 also known as protein-tyrosine phosphatase 1D or protein-tyrosine phosphatase 2C is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a protein tyrosine phosphatase Shp2.PTPN11 is a member of the protein tyrosine phosphatase ...
, PTPN6
PTPN6
Tyrosine-protein phosphatase non-receptor type 6 is an enzyme that in humans is encoded by the PTPN6 gene.Also known as Src homology region 2 domain-containing phosphatase-1 .-Interactions:...
, PITPNM1
PITPNM1
Membrane-associated phosphatidylinositol transfer protein 1 is a protein that in humans is encoded by the PITPNM1 gene.-Further reading:...
, Gelsolin
Gelsolin
Gelsolin is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily, as it severs with nearly 100% efficiency...
, Src
Src (gene)
Proto-oncogene tyrosine-protein kinase Src is an enzyme that in humans is encoded by the SRC gene.Src is a proto-oncogene encoding a tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus, for which they won the 1989 Nobel Prize in Physiology or Medicine. It belongs to a...
, GRIN2A
GRIN2A
Glutamate [NMDA] receptor subunit epsilon-1 is a protein that in humans is encoded by the GRIN2A gene.-Interactions:GRIN2A has been shown to interact with FYN, DLG4, DLG3, DLG1, Src, PTK2B and Interleukin 16.-Further reading:...
, Ewing sarcoma breakpoint region 1
Ewing sarcoma breakpoint region 1
RNA-binding protein EWS is a protein that in humans is encoded by the EWSR1 gene.-Interactions:Ewing sarcoma breakpoint region 1 has been shown to interact with POU4F1, SF1, BARD1, Small nuclear ribonucleoprotein polypeptide C, PTK2B and Zinc finger protein 165.ERG, ATF-1,-External links:* on the...
, RB1CC1
RB1CC1
RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.-Interactions:RB1CC1 has been shown to interact with PTK2B, ASK1 and PTK2.-Further reading:...
, TGFB1I1
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein is a protein that in humans is encoded by the TGFB1I1 gene.-Interactions:TGFB1I1 has been shown to interact with PTPN12, PTK2, Androgen receptor, PTK2B, Dopamine transporter and Hsp27....
, NPHP1
NPHP1
Nephrocystin-1 is a protein that in humans is encoded by the NPHP1 gene.-Interactions:NPHP1 has been shown to interact with BCAR1, PTK2B, Filamin and INVS.-Further reading:...
, BCAR1
BCAR1
Breast cancer anti-estrogen resistance protein 1 is a protein that in humans is encoded by the BCAR1 gene.-External links:* Info with links in the...
, FYN
FYN
Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that in humans is encoded by the FYN gene.This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth...
, DLG4
DLG4
PSD-95 also known as SAP-90 is a protein that in humans is encoded by the DLG4 gene....
, DLG3
DLG3
Disks large homolog 3 also known as neuroendocrine-DLG or synapse-associated protein 102 is a protein that in humans is encoded by the DLG3 gene...
, DDEF2
DDEF2
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the ASAP2 gene.-Further reading:...
, Cbl gene
Cbl gene
Cbl is a mammalian gene encoding several proteins including E3 ubiquitin-protein ligase CBL involved in cell signalling and protein ubiquitination...
, RAS p21 protein activator 1
RAS p21 protein activator 1
RAS p21 protein activator 1 or RasGAP , also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal activities:...
, Paxillin
Paxillin
Paxillin is a signal transduction adaptor protein discovered in 1990 in the laboratory of Keith Burridge and should not be confused with the neurotoxin paxilline. The C-terminal region of paxillin contains four LIM domains that target paxillin to focal adhesions, it is presumed through a direct...
and SORBS2
SORBS2
Sorbin and SH3 domain-containing protein 2 is a protein that in humans is encoded by the SORBS2 gene.-Interactions:SORBS2 has been shown to interact with PTK2B, Cbl gene, ABL2 and Abl gene.-Further reading:...
.