PIN1
Encyclopedia
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 is an enzyme
that in humans is encoded by the PIN1 gene
.
with CSNK2A2
, Casein kinase 2, alpha 1, Wee1-like protein kinase
, FOXO4
, CDC25C
, CDC27
, MYT1
, PLK1
, MPHOSPH1
, DAB2
, P53
, PKMYT1
, C-jun
, SUPT5H
, Mothers against decapentaplegic homolog 3
and Mothers against decapentaplegic homolog 2
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the PIN1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
PIN1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with CSNK2A2
CSNK2A2
Casein kinase II subunit alpha is an enzyme that in humans is encoded by the CSNK2A2 gene.-Interactions:CSNK2A2 has been shown to interact with CSNK2B, FGF1, PTEN, RELA, ATF1, Nucleolin, CREB binding protein, Activating transcription factor 2, PIN1, C-jun and C-Fos.-Further reading:...
, Casein kinase 2, alpha 1, Wee1-like protein kinase
Wee1-like protein kinase
WEE1 homolog , also known as WEE1, is a protein which in humans is encoded by the WEE1 gene.- Function :This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases...
, FOXO4
FOXO4
Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.-Interactions:FOXO4 has been shown to interact with PIN1 and Mdm2.-Further reading:...
, CDC25C
CDC25C
M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene.-Interactions:CDC25C has been shown to interact with MAPK14, CHEK1, PCNA, PIN1, PLK3 and NEDD4.-Further reading:...
, CDC27
CDC27
Cell division cycle protein 27 homolog is a protein that in humans is encoded by the CDC27 gene.-Interactions:CDC27 has been shown to interact with ANAPC1, ANAPC4, ANAPC5, ANAPC11, FZR1, CDC20, CDH1, CDC23, PIN1, CDC16, ANAPC7, MAD2L1 and ANAPC10....
, MYT1
MYT1
Myelin transcription factor 1 is a protein that in humans is encoded by the MYT1 gene.- External links :...
, PLK1
PLK1
Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 or serine/threonine-protein kinase 13 , is an enzyme that in humans is encoded by the PLK1 gene.- Structure :...
, MPHOSPH1
MPHOSPH1
Kinesin-like protein KIF20B is a protein that in humans is encoded by the KIF20B gene.-Further reading:...
, DAB2
DAB2
Disabled homolog 2 is a protein that in humans is encoded by the DAB2 gene.-Interactions:DAB2 has been shown to interact with C-src tyrosine kinase, Cdk1, Src, LRP2, DVL3, PIN1, MYO6, DVL2, DAB2IP, Mothers against decapentaplegic homolog 3 and Mothers against decapentaplegic homolog 2.-Further...
, P53
P53
p53 , is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer...
, PKMYT1
PKMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase is an enzyme that in humans is encoded by the PKMYT1 gene.-Interactions:PKMYT1 has been shown to interact with PIN1 and STEAP3.-Further reading:...
, C-jun
C-jun
c-Jun is the name of a gene and protein that, in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the...
, SUPT5H
SUPT5H
Transcription elongation factor SPT5 is a protein that in humans is encoded by the SUPT5H gene.-Interactions:SUPT5H has been shown to interact with Cyclin-dependent kinase 7, PIN1, CDK9, HTATSF1, POLR2A, PRMT1 and Protein arginine methyltransferase 5....
, Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins.The human SMAD3 gene is located on chromosome 15...
and Mothers against decapentaplegic homolog 2
Mothers against decapentaplegic homolog 2
Mothers against decapentaplegic homolog 2 also known as SMAD family member 2 or SMAD2 is a protein that in humans is encoded by the SMAD2 gene. MAD homolog 2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' and the C....
.