Ozzy & Drix
Encyclopedia
Ozzy & Drix, also known as The Fantastic Voyage Adventures of Osmosis Jones & Drixenol and Osmosis Jones: The Animated Series, is an American
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 animated
Animation
Animation is the rapid display of a sequence of images of 2-D or 3-D artwork or model positions in order to create an illusion of movement. The effect is an optical illusion of motion due to the phenomenon of persistence of vision, and can be created and demonstrated in several ways...

 television series
Television program
A television program , also called television show, is a segment of content which is intended to be broadcast on television. It may be a one-time production or part of a periodically recurring series...

 based on the Warner Bros.
Warner Bros.
Warner Bros. Entertainment, Inc., also known as Warner Bros. Pictures or simply Warner Bros. , is an American producer of film and television entertainment.One of the major film studios, it is a subsidiary of Time Warner, with its headquarters in Burbank,...

 film Osmosis Jones
Osmosis Jones
Osmosis Jones is a 2001 live-action/animated comedy film directed by Tom Sito and Piet Kroon for the animated segments and the Farrelly brothers for the live-action segments...

and it was produced by Warner Bros. Animation
Warner Bros. Animation
Warner Bros. Animation is the animation division of Warner Bros., a subsidiary of Time Warner. The studio is closely associated with the Looney Tunes and Merrie Melodies characters, among others. The studio is the successor to Warner Bros...

. It takes place inside the body of teenager Hector Cruz (referred to by the characters as "the City of Hector"). The series premiered on September 14, 2002 on the Kids' WB
Kids' WB
Kids' WB! was Warner Bros. American childrens programing division brand for The WB Television Network. In September 2006, the block moved to The CW Television Network. The CW is the result of The WB's merger with UPN in 2006...

; the final episode aired July 5, 2004. Unlike the original movie it spun off from, Ozzy & Drix was entirely animated and contained no live action. It stars Phil LaMarr
Phil LaMarr
Phillip "Phil" LaMarr is an American actor, comedian and voice actor. One of the original cast members on the sketch comedy series MADtv, he is also known for his small, but memorable role as Marvin in Pulp Fiction...

 as the replacement for Chris Rock
Chris Rock
Christopher Julius "Chris" Rock III is an American comedian, actor, screenwriter, television producer, film producer and director. He was voted in the US as the 5th greatest stand-up comedian of all time by Comedy Central...

 as Osmosis Jones, and Jeff Bennett
Jeff Bennett
Jeffrey Glenn "Jeff" Bennett is an American voice actor and musician, listed "among the top names in the voice-over field", best known as the voice of Johnny Bravo in the series of the same name...

 as the replacement for David Hyde Pierce
David Hyde Pierce
David Hyde Pierce is an American actor and comedian best known for playing psychiatrist Dr. Niles Crane on the NBC sitcom Frasier, for which he received many accolades including four Emmy Awards for Outstanding Supporting Actor in a Comedy Series.-Early life:Pierce, the youngest of four siblings,...

 as Drix. As of July 2011, episodes of the series are still available via the Kids WB website.
The show also aired on Teletoon
Télétoon (Canadian TV channel)
Télétoon is a Canadian French language Category A specialty channel that specializes in animation programming. Télétoon is owned by Teletoon Canada Inc; a 50/50 partnership between Astral Media and Corus Entertainment...

 in Canada.
The show is also slightly less violent than the movie, having the characters treated like people rather than simply cells, and having none of them killed off, unlike the movie where Thrax managed to kill off several cells.

Summary

A few years after Ozzy and Drix defeated Thrax and saved Frank from Osmosis Jones
Osmosis Jones
Osmosis Jones is a 2001 live-action/animated comedy film directed by Tom Sito and Piet Kroon for the animated segments and the Farrelly brothers for the live-action segments...

, Ozzy and Drix chase a scarlet fever
Scarlet fever
Scarlet fever is a disease caused by exotoxin released by Streptococcus pyogenes. Once a major cause of death, it is now effectively treated with antibiotics...

 bacterium. While doing that, Ozzy, Drix and the germ get sucked up from Frank by a mosquito
Mosquito
Mosquitoes are members of a family of nematocerid flies: the Culicidae . The word Mosquito is from the Spanish and Portuguese for little fly...

 and arrive on young 13-year old boy named Hector Cruz's body. Installed as Private Investigator
Private investigator
A private investigator , private detective or inquiry agent, is a person who can be hired by individuals or groups to undertake investigatory law services. Private detectives/investigators often work for attorneys in civil cases. Many work for insurance companies to investigate suspicious claims...

s, the partners vow to protect the well being of Hector from any viral threat.

Main characters

Osmosis "Ozzy" Jones (Phil LaMarr
Phil LaMarr
Phillip "Phil" LaMarr is an American actor, comedian and voice actor. One of the original cast members on the sketch comedy series MADtv, he is also known for his small, but memorable role as Marvin in Pulp Fiction...

) - An urban and funky white blood cell
White blood cell
White blood cells, or leukocytes , are cells of the immune system involved in defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a...

 with little respect for authority. He works as a private-eye in the city of Hector. He and Drix were originally from the city of Frank, the character portrayed in the movie, although they were transferred to Hector through a mosquito while chasing a scarlet fever virus aptly named Scarlet. As most crime-fighting heroes do, Ozzy has a nearly unlimited amount of smart remarks that he uses frequently when fighting viruses, as well as sarcasm for anyone else.

Agent "Drixobensometapetramine"/"Drix" Koldriliff (Jeff Bennett) - A straight-laced and by-the-book cold pill and Ozzy's fellow private eye. They have an office inside Hector's left retina
Retina
The vertebrate retina is a light-sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera. Light striking the retina initiates a cascade of chemical and electrical...

 ("prime real estate"). His right arm is a multi-launcher which launches various chemical containers stored in his torso though the most common is an ice pill which freezes villains. The right arm also contains a phone, and other gadgets including an eggbeater (apparently the only thing the arm can't do is make a decent milkshake),and a crude clamp-like claw usable as a hand. Drix's cautiousness and complete honesty (making him quite gullible), puts him at odds with the devil-may-care Ozzy. He often tries to "fit in" with the other cells in the body, usually failing to comprehend the concepts.

Hector Cruz (a.k.a. The City of Hector) (Justin Cowden) - The Cuban American
Cuban American
A Cuban American is a United States citizen who traces his or her "national origin" to Cuba. Cuban Americans are also considered native born Americans with Cuban parents or Cuban-born persons who were raised and educated in US...

 teenager that the show revolves around. He is foolhardy, a risk taker, and somewhat ignorant, all probably to further the show's plot. He reminds Ozzy of Frank at Hector's age, reminded him that this was the age where Frank's life took a turn for the worse so decides to stay to prevent that from happening. In one episode when Hector went on a white water rafting trip with his older cousin he got Appendicitis
Appendicitis
Appendicitis is a condition characterized by inflammation of the appendix. It is classified as a medical emergency and many cases require removal of the inflamed appendix, either by laparotomy or laparoscopy. Untreated, mortality is high, mainly because of the risk of rupture leading to...

, he was rushed to a hospital and had surgery. Hector has a dog named Uno, an older sister, and a mother and father. In another episode Hector learned a lesson in proper dental hygiene when he got a cavity
Dental caries
Dental caries, also known as tooth decay or a cavity, is an irreversible infection usually bacterial in origin that causes demineralization of the hard tissues and destruction of the organic matter of the tooth, usually by production of acid by hydrolysis of the food debris accumulated on the...

 from eating too much sugar.

City of Hector

Police
  • Maria Amino (Tasia Valenza
    Tasia Valenza
    Tasia Valenza is an American actress who has most recently found acclaim as a voice actor.- Television :...

    ) - A white blood cell and a cop in the city of Hector. She speaks with a Hispanic accent. She is highly skilled at fighting and possibly the most competent cop inside of Hector except for Ozzy. She has shown to have a crush on Drix throughout the series. Her name comes from the amino acid
    Amino acid
    Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen...

     and is also Ozzy's new love interest.
  • Chief Gluteus (Jim Cummings
    Jim Cummings
    James Jonah "Jim" Cummings is an American voice actor who has appeared in almost 100 roles. He has appeared in classic animated movies such as Aladdin and The Lion King, as well as taking on roles in more current films, such as Bee Movie, Princess and the Frog, and Winnie the Pooh.-Personal...

    ) - A gruff and serious old muscle cell and the Chief of Police for the city of Hector. He dislikes both Ozzy and Drix and prefers to handle things himself, which often results in disasters. His name is from Gluteus Maximus, the scientific name for the muscles in the buttock.


Government
  • Mayor Paul Spryman (Alanna Ubach
    Alanna Ubach
    Alanna Noel Ubach is an American actress and voice actress. She is known for her roles in Legally Blonde as Serena and Meet the Fockers as Isabel Villalobos...

    ) - The naughty little mayor of the city of Hector. Unlike Mayor Phlegmming where he is an adult and acted mature and gentlemen-like from the film Osmosis Jones
    Osmosis Jones
    Osmosis Jones is a 2001 live-action/animated comedy film directed by Tom Sito and Piet Kroon for the animated segments and the Farrelly brothers for the live-action segments...

    , he is approximately the same age as Hector, and acts very immaturely, taking all the credit for the round-ups Ozzy and Drix make. His decisions often put Hector's health in extreme danger as well as sometimes being completely ridiculous, where Maria commented that he once ordered all the cells to go to the left side to see if Hector would tip over.
  • Ellen Patella (Vivica A. Fox
    Vivica A. Fox
    Vivica Anjanetta Fox is an American actress and television producer. She is best known for her roles in the films Independence Day, Set It Off, Soul Food, Why Do Fools Fall In Love,Kill Bill and Juwanna Mann....

    ) - An attorney-at-law who helps new cells find their place in Hector. Ozzy has a small crush on her as well, although she has no interest in him.


Other
  • The Mole (Jeffrey Tambor
    Jeffrey Tambor
    Jeffrey Michael Tambor is an American actor, perhaps best known for his roles as George Bluth Sr. and Oscar Bluth on Arrested Development and Hank Kingsley on The Larry Sanders Show.-Early life:...

    ) - A former secret agent, and klutz, and generally used as comic relief, he has his own adrenaline supply, and in every one of his appearances he tries to "vanish mysteriously" (failing to do so every time in comical ways). He is mostly known as very paranoid, often thinking that he is being hunted down, or people are watching him. Despite this he has a lot of contacts and apparently nothing happens in Hector that he doesn't know about, this makes him a good source of information. His role is similar to the flu shot from the movie.
  • Penicillin G (Julian Sands
    Julian Sands
    Julian M. Sands is an English actor, known for his roles in the Best Picture nominee The Killing Fields, the cult film Warlock, A Room with a View, Arachnophobia, Vatel, the television series 24 and as Jor-El in the television series Smallville.-Career:Sands began his film career appearing in...

    ) - A Penicillin injected into Hector to help fight Strepfinger. He is charming, responsible, and amazingly intelligent. He currently patrols Hector's lungs. He is an obvious parody of James Bond
    James Bond (character)
    Royal Navy Commander James Bond, CMG, RNVR is a fictional character created by journalist and novelist Ian Fleming in 1953. He is the main protagonist of the James Bond series of novels, films, comics and video games...

    .
  • Dander (Frank Welker
    Frank Welker
    Franklin Wendell "Frank" Welker is an American actor who specializes in voice acting and has contributed character voices and other vocal effects to American television and motion pictures.-Acting career:...

    ) - Drix's pet dog germ that came from Hector's dog Uno, formed from the dog's saliva inside Hector's nostril. Like cells, he can shapeshift and often changes his head into Ozzy.
  • Travis (Rob Paulsen
    Rob Paulsen
    Robert Fredrick "Rob" Paulsen III , sometimes credited as Rob Paulson, is an American voice actor, best known as the voice behind Raphael from the 1987 cartoon of Teenage Mutant Ninja Turtles, Yakko Warner and Dr...

    ) - Hector's classmate and best friend. He is an American with Asian origin.


The Supplements:
  • Vitamin A
    Vitamin A
    Vitamin A is a vitamin that is needed by the retina of the eye in the form of a specific metabolite, the light-absorbing molecule retinal, that is necessary for both low-light and color vision...

    (Phil LaMarr
    Phil LaMarr
    Phillip "Phil" LaMarr is an American actor, comedian and voice actor. One of the original cast members on the sketch comedy series MADtv, he is also known for his small, but memorable role as Marvin in Pulp Fiction...

    ): The leader of the Supplements who lead his team to victory by stopping the Lead-Heads who were attempting to infect Hector. Unlike Ozzy, he is very by-the-book, and has a slight resemblance to Superman
    Superman
    Superman is a fictional comic book superhero appearing in publications by DC Comics, widely considered to be an American cultural icon. Created by American writer Jerry Siegel and Canadian-born American artist Joe Shuster in 1932 while both were living in Cleveland, Ohio, and sold to Detective...

    .
  • Iron
    Iron
    Iron is a chemical element with the symbol Fe and atomic number 26. It is a metal in the first transition series. It is the most common element forming the planet Earth as a whole, forming much of Earth's outer and inner core. It is the fourth most common element in the Earth's crust...

    (Phil LaMarr
    Phil LaMarr
    Phillip "Phil" LaMarr is an American actor, comedian and voice actor. One of the original cast members on the sketch comedy series MADtv, he is also known for his small, but memorable role as Marvin in Pulp Fiction...

    ): A strong, yet short tempered member of the Supplements, and the only one with no cape. Iron is a parody of the Thing
    Thing (comics)
    The Thing is a fictional character, a founding member of the superhero team known as the Fantastic Four in the Marvel Comics universe. He was created by Jack Kirby and Stan Lee in The Fantastic Four #1...

     from Fantastic Four
    Fantastic Four
    The Fantastic Four is a fictional superhero team appearing in comic books published by Marvel Comics. The group debuted in The Fantastic Four #1 , which helped to usher in a new level of realism in the medium...

    .
  • B Complex (Jim Cummings
    Jim Cummings
    James Jonah "Jim" Cummings is an American voice actor who has appeared in almost 100 roles. He has appeared in classic animated movies such as Aladdin and The Lion King, as well as taking on roles in more current films, such as Bee Movie, Princess and the Frog, and Winnie the Pooh.-Personal...

    ): B Complex has 3 heads and 4 legs, but only 2 arms.
  • Vitamine D (Rob Paulsen
    Rob Paulsen
    Robert Fredrick "Rob" Paulsen III , sometimes credited as Rob Paulson, is an American voice actor, best known as the voice behind Raphael from the 1987 cartoon of Teenage Mutant Ninja Turtles, Yakko Warner and Dr...

    ): A fast, egotistical member of the Supplements.
  • Vitamine E (Nancy Lenari): The only three-eyed female of the Supplements, who encouraged Drix to join the team.


Help from the City of Hector:
  • Captain Quinine (James Belushi
    James Belushi
    James Adam "Jim" Belushi is an American actor, comedian, and musician. He is the younger brother of comic actor John Belushi.-Early life:Belushi was born in Chicago...

    ) A captain who lost his leg in a stomach acid accident (parodying Captain Ahab of Moby Dick).
  • The Current Dreams Studio Head (Kevin Michael Richardson
    Kevin Michael Richardson
    Kevin Michael Richardson is an American actor and voice actor who currently stars as Cleveland Brown, Jr. in The Cleveland Show...

    ): A small studio head of the subconscious network, who used a holographic head to be more powerful and scary, like the wizard in The Wizard of Oz
    The Wizard of Oz (1939 film)
    The Wizard of Oz is a 1939 American musical fantasy film produced by Metro-Goldwyn-Mayer. It was directed primarily by Victor Fleming. Noel Langley, Florence Ryerson and Edgar Allan Woolf received credit for the screenplay, but there were uncredited contributions by others. The lyrics for the songs...

    .
  • Loretta Epstein-Barr (Kathy Najimy
    Kathy Najimy
    Kathy Ann Najimy is an American actress, most notable as Olive Massery on the television series Veronica's Closet, Sister Mary Patrick in Sister Act and the voice of Peggy Hill on the animated television series King of the Hill. Prior to her film work, she was best known for two Off Broadway shows...

    ): The vice president of the subconscious network, who explained why the studio keeps rerunning the nightmare Hector was having.
  • Auntie Histamine (Andrea Martin
    Andrea Martin
    Andrea Louise Martin is an American and Canadian actress and comedienne. She has appeared in films such as My Big Fat Greek Wedding, on stage in productions such as My Favorite Year, Fiddler on the Roof and Candide, and in the television series, SCTV.-Personal life:Martin, the oldest of three...

    ): Drix's auntie, who used to read lists of synthesised amino acids when Drix was young. But she accidentally became a villain when Hector abuses his nose spray when he had a cold. So when Hector uses the spray, Auntie becomes hysterical and drains all the liquids on Hector, which could have been damaging to his nose.


Humans:
  • Hector's Dad (Joe Lala
    Joe Lala
    Joe Lala is an actor and voice actor, notable for his dubbing of Kun Lan of the video-game Killer7.He also played drums and percussion on 32 gold and 28 platinum albums. His credits include Blues Image, Crosby, Stills, Nash & Young, Manassas, The Bee Gees, Whitney Houston, and many...

    ): Hector's father is a helpful is very serious and strongly observant when it comes to Hector's health, attitude, and his school reports.
  • Hector's Mom (Alanna Ubach
    Alanna Ubach
    Alanna Noel Ubach is an American actress and voice actress. She is known for her roles in Legally Blonde as Serena and Meet the Fockers as Isabel Villalobos...

    ) Hector's mother is always looking out for Hector's health, since he is still a teenager and doesn't listen to her sometimes.
  • Hector's Sister (Alanna Ubach
    Alanna Ubach
    Alanna Noel Ubach is an American actress and voice actress. She is known for her roles in Legally Blonde as Serena and Meet the Fockers as Isabel Villalobos...

    ): She is always starting an argument with Hector, because she is the older sister.
  • Chistine Kolchuck (Kimberly Brooks
    Kimberly Brooks
    Kimberly Brooks is an American voice actress in the anime, feature films, video games, and theatre industry. She started her acting career when she was nine....

    : She is very sweet and kind, not to mention Hector's crush. Ozzy even helped save Christine from the Pneumoniac.


The City of Christine:
  • Mayor Concious Santorini (Cree Summer
    Cree Summer
    Cree Summer Francks , best known as Cree Summer, is a Canadian actress, musician and voice actress. She is perhaps best known for her role as college student Winifred "Freddie" Brooks on the NBC sitcom A Different World...

    ): She is the mayor of Christine, and she is more smart and responsible than Spryman. She even said that everyone in Christine are fans of Hector.
  • Cilia Tyson (Dawnn Lewis
    Dawnn Lewis
    Dawnn Lewis is an American actress and singer, perhaps best known for her roles on sitcoms such as A Different World and in the first season of Hangin' with Mr. Cooper.-Career:...

    ): Cilia is a cop in Christine who helped Ozzy stop the Pneumoniac and prove that Maximus is a trator to the city. She was made the new police chief by the mayor.
  • Drixeen (Miriam Flynn
    Miriam Flynn
    Miriam Flynn is an American voice actress and character actress. She is best known as Cousin Catherine in the National Lampoon's Vacation franchise. As a voice artist, she has been featured in The Land Before Time series, Taz-Mania as the title character's mother, Jean, Poil in The Spooktacular...

    ): She is a dear friend to Cilia and she used to a cold pill. She looks a bit like Drix except she's green, has hair, and a right hand and left cannon, while Drix is red, has no hair, and his arm positions are the other way.

Germs and viruses

  • Ernst Strepfinger
    Strep throat
    Streptococcal pharyngitis, streptococcal tonsillitis, or streptococcal sore throat is a type of pharyngitis caused by a group A streptococcal infection. It affects the pharynx including the tonsils and possibly the larynx. Common symptoms include fever, sore throat, and enlarged lymph nodes...

    (Brad Garrett
    Brad Garrett
    Bradley "Brad" Garrett is an American actor, voice actor, stand-up comedian, and professional poker player. Throughout he has appeared in numerous television and film roles....

     and Jim Cummings
    Jim Cummings
    James Jonah "Jim" Cummings is an American voice actor who has appeared in almost 100 roles. He has appeared in classic animated movies such as Aladdin and The Lion King, as well as taking on roles in more current films, such as Bee Movie, Princess and the Frog, and Winnie the Pooh.-Personal...

    ) - A powerful germ
    Microorganism
    A microorganism or microbe is a microscopic organism that comprises either a single cell , cell clusters, or no cell at all...

     whose goal is to make Hector sick. He has a large gangbang of horny germs and viruses to do his dirty work. In "Strepfinger", Strepfinger is planning on giving Hector a nasty case of pneumonia
    Pneumonia
    Pneumonia is an inflammatory condition of the lung—especially affecting the microscopic air sacs —associated with fever, chest symptoms, and a lack of air space on a chest X-ray. Pneumonia is typically caused by an infection but there are a number of other causes...

    , but in the end, he gets sucked out from his hideout in the lungs along with his pet. In "Ozzy Jr.", Strepfinger returns, but this time he has an eye patch on his right eye and his pet has an eye patch, too. He plans to infect Hector with bacteria. In "Lights Out", Ozzy and Drix use his resources to break into the Central Data Bank when everyone forgets who they are after Hector suffers a concussion. In "Tricky Ricardo", he tricks Ricardo into thinking that he is working for Strepfinger, who was planning to give Hector cancer
    Cancer
    Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...

    , but in the end, Strepfinger gets stuck on one of the cotton balls and fell down the drain of the shower. Strepfinger is a parody of the stereotypical Bond villain with a particular emphasis on Auric Goldfinger
    Auric Goldfinger
    Auric Goldfinger is a fictional character and the main antagonist in the James Bond film and novel Goldfinger. His first name, Auric, is an adjective meaning of gold...

     and Ernst Stavro Blofeld
    Ernst Stavro Blofeld
    Ernst Stavro Blofeld is a fictional character and a supervillain from the James Bond series of novels and films, who was created by Ian Fleming and Kevin McClory. An evil genius with aspirations of world domination, he is the archenemy of the British Secret Service agent James Bond and is arguably...

    .
  • Mother Louse
    Louse
    Lice is the common name for over 3,000 species of wingless insects of the order Phthiraptera; three of which are classified as human disease agents...

    - A louse that laid its eggs on Hectors hair.
  • Rhoda Virus
    Rotavirus
    Rotavirus is the most common cause of severe diarrhoea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. It is a genus of double-stranded RNA virus in the family Reoviridae. By the age of five,...

    (Justine Bateman
    Justine Bateman
    Justine Tanya Bateman is an American actress, writer, and producer. She is best known for her regular role as Mallory Keaton on the sitcom Family Ties...

    ) - An intestinal virus that plans on giving Hector a bad case of gastroenteritis
    Gastroenteritis
    Gastroenteritis is marked by severe inflammation of the gastrointestinal tract involving both the stomach and small intestine resulting in acute diarrhea and vomiting. It can be transferred by contact with contaminated food and water...

    . Unfortunately, for her, Hector had a 12 bean salad, which gave him a gas attack, and the gas is deadly to her and her gang, so Rota diguises herself as a submarine captain to take Ozzy, Drix, and Maria into the intestines to destroy the Great White Bean. In the end, she and her minions are trapped in a gas bubble, killing them.
  • Protozilla (Frank Welker
    Frank Welker
    Franklin Wendell "Frank" Welker is an American actor who specializes in voice acting and has contributed character voices and other vocal effects to American television and motion pictures.-Acting career:...

    ) - An allergen with a weak form and a monster form with his monster form only usable in a body that is allergic to him, however Ice pills cause him to revert back to his normal form. His most defining feature is that he has 2 thumbs which gives him away as the allergy. He was a giant monster that terrorized the city of Hector and made it look like it was Drix's dog who was causing the disaster (meanwhile, outside of Hector, Hector himself had a dog and his mother believed the dog was causing his allergies). Ozzy, Drix and Drix's dog confronted Protozilla at Hector's nose and when Hector sneezed, Protozilla was sucked out and killed. And back with Hector, it was revealed his allergies are really from a certain flower
    Pollen
    Pollen is a fine to coarse powder containing the microgametophytes of seed plants, which produce the male gametes . Pollen grains have a hard coat that protects the sperm cells during the process of their movement from the stamens to the pistil of flowering plants or from the male cone to the...

     his mother was bringing in and not the dog.
  • Smirch (Danny Bonaduce
    Danny Bonaduce
    Dante Daniel "Danny" Bonaduce is an American radio/television personality, comedian, professional wrestler, and former child actor...

    ) - An acne germ that plans to make Hector get a zit
    Acne vulgaris
    Acne vulgaris is a common human skin disease, characterized by areas of skin with seborrhea , comedones , papules , pustules , Nodules and possibly scarring...

     ("Street Up"). He also managed to trick Drix when he wanted to learn how to be cool. Actually, Drix helped him to get into a sebum oil refinery, so he had an opportunity to grow gigantic and give Hector a zit—right on Picture Day. Drix defeats him by dropping sodium bicarbonate
    Sodium bicarbonate
    Sodium bicarbonate or sodium hydrogen carbonate is the chemical compound with the formula Na HCO3. Sodium bicarbonate is a white solid that is crystalline but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda . The natural mineral form is...

     toothpaste on him, shrinking him down to a tiny size, so that he's captured.
  • Nick O' Teen
    Nicotine
    Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...

    (Tim Curry
    Tim Curry
    Timothy James "Tim" Curry is a British actor, singer, composer and voice actor, known for his work in a diverse range of theatre, film and television productions. He currently resides in Los Angeles, California....

    ) - A tobacco
    Tobacco
    Tobacco is an agricultural product processed from the leaves of plants in the genus Nicotiana. It can be consumed, used as a pesticide and, in the form of nicotine tartrate, used in some medicines...

     addictive that plans to make Hector addicted to smoking ("Where There's Smoke"). Nick can shapeshift and release clouds of smoke that brainwash cells and makes them do Nick's evil bidding, becoming more powerful the more cells he controls. He has three lackeys: Butane
    Butane
    Butane is a gas with the formula C4H10 that is an alkane with four carbon atoms. The term may refer to any of two structural isomers, or to a mixture of them: in the IUPAC nomenclature, however, butane refers only to the unbranched n-butane isomer; the other one being called "methylpropane" or...

     (Jeff Bennett), Carbon Monoxide
    Carbon monoxide
    Carbon monoxide , also called carbonous oxide, is a colorless, odorless, and tasteless gas that is slightly lighter than air. It is highly toxic to humans and animals in higher quantities, although it is also produced in normal animal metabolism in low quantities, and is thought to have some normal...

     (Tara Strong
    Tara Strong
    Tara Lyn Strong is a Canadian actress, voice-over artist, singer, who is best known for her voice work in cartoons.-Early life and career:...

    ), and Tar
    Tar
    Tar is modified pitch produced primarily from the wood and roots of pine by destructive distillation under pyrolysis. Production and trade in tar was a major contributor in the economies of Northern Europe and Colonial America. Its main use was in preserving wooden vessels against rot. The largest...

     (Frank Welker
    Frank Welker
    Franklin Wendell "Frank" Welker is an American actor who specializes in voice acting and has contributed character voices and other vocal effects to American television and motion pictures.-Acting career:...

    ). Nick's lackeys were killed before him in confrontations with Ozzy and Drix but when Nick was finally powerful enough to hold Ozzy and Drix back from foiling his plans, Hector decided not to smoke anymore in favor of Christine and Nick was weakened by him breaking the addiction, giving Ozzy the chance to squash him under his shoe.
  • Sal Monella
    Salmonella
    Salmonella is a genus of rod-shaped, Gram-negative, non-spore-forming, predominantly motile enterobacteria with diameters around 0.7 to 1.5 µm, lengths from 2 to 5 µm, and flagella which grade in all directions . They are chemoorganotrophs, obtaining their energy from oxidation and reduction...

    (Henry Winkler
    Henry Winkler
    Henry Franklin Winkler, OBE is an American actor, director, producer, and author.Winkler is best known for his role as Fonzie on the 1970s American sitcom Happy Days...

    ) - A gangster germ who enters the city of Hector on a Rusty Dog, which Hector does not know was tainted, and plans to dump illegal toxic waste in Hector's stomach. To make matters worse, Mayor Spryman was his hostage. But his plans were destroyed when Ozzy and Drix made Hector vomit by going on this ride at Rustyland called "The Barfy Bungee", and the mayor was rescued and brought back to the city.
  • Sylvian Fisher (Brian Posehn
    Brian Posehn
    Brian Edmund Posehn is an American actor, voice actor, musician and comedian, known for his roles as mail clerk Kevin Liotta on NBC's Just Shoot Me!, a cast member and writer on HBO's Mr. Show, and most recently as Brian Spukowski on Comedy Central's The Sarah Silverman Program.-Early life:Posehn...

    ): A nerdy brain cell who was trying to become mayor in the upcoming election. He planned to use a growth formula
    Formula
    In mathematics, a formula is an entity constructed using the symbols and formation rules of a given logical language....

     to make Hector grow uncontrollably and blame it on Spryman's carelessness. His name comes from the Sylvian fissure brain area.
  • General Malaise
    Streptococcus mutans
    Streptococcus mutans is a facultatively aerobic, Gram-positive coccus-shaped bacterium commonly found in the human oral cavity and is a significant contributor to tooth decay.The microbe was first described by J Kilian Clarke in 1924.-Introduction:...

    (Charlie Adler) - A bacterium
    Bacteria
    Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...

     who uses sugar
    Sugar
    Sugar is a class of edible crystalline carbohydrates, mainly sucrose, lactose, and fructose, characterized by a sweet flavor.Sucrose in its refined form primarily comes from sugar cane and sugar beet...

     to make his army of bacteria multiply. He develops evil plots to make Hector eat sugar. Of course, he and all his troops were killed when they were in Hector's teeth and he was visiting the dentist. They fell out through a sink to die off. They also dissolve when they eat salt. General Malaise is an obvious parody of Napoleon Bonaparte.
  • Professor Nightmare - A nightmare that originated from a movie Hector saw. Ozzy and Drix enter Hector's dreams and help him overcome his fear and crush the nightmare.
  • Chief Maximus (Rob Paulsen
    Rob Paulsen
    Robert Fredrick "Rob" Paulsen III , sometimes credited as Rob Paulson, is an American voice actor, best known as the voice behind Raphael from the 1987 cartoon of Teenage Mutant Ninja Turtles, Yakko Warner and Dr...

    ) - The Chief of Police in the city of Christine (a girl that Hector likes) that teams up with the Pneumoniac.
  • The Pneumonia
    Pneumonia
    Pneumonia is an inflammatory condition of the lung—especially affecting the microscopic air sacs —associated with fever, chest symptoms, and a lack of air space on a chest X-ray. Pneumonia is typically caused by an infection but there are a number of other causes...

    c
    (Pat Fraley
    Pat Fraley
    Patrick "Pat" Fraley is an American voice actor, who is best known as the voice of Krang, Casey Jones and numerous other characters from Teenage Mutant Ninja Turtles...

    ) - A germ who is planning to give Christine pneumonia
    Pneumonia
    Pneumonia is an inflammatory condition of the lung—especially affecting the microscopic air sacs —associated with fever, chest symptoms, and a lack of air space on a chest X-ray. Pneumonia is typically caused by an infection but there are a number of other causes...

     ("An Out of Body Experience parts 1 & 2").
  • Mother Worm (Frank Welker
    Frank Welker
    Franklin Wendell "Frank" Welker is an American actor who specializes in voice acting and has contributed character voices and other vocal effects to American television and motion pictures.-Acting career:...

    ) - A Trichinella spiralis
    Trichinella spiralis
    Trichinella spiralis is a nematode parasite, occurring in rats, pigs, bears and humans, and is responsible for the disease trichinosis. It is sometimes referred to as the "pork worm" due to it being found commonly in undercooked pork products...

     worm that came from a sausage Hector barely cooked. It is very reminiscent of Japanese monsters especially Godzilla
    Godzilla
    is a daikaijū, a Japanese movie monster, first appearing in Ishirō Honda's 1954 film Godzilla. Since then, Godzilla has gone on to become a worldwide pop culture icon starring in 28 films produced by Toho Co., Ltd. The monster has appeared in numerous other media incarnations including video games,...

    , even having atomic breath. Had it been left unchecked, she could have caused a massive outbreak of trichinosis
    Trichinosis
    Trichinosis, also called trichinellosis, or trichiniasis, is a parasitic disease caused by eating raw or undercooked pork or wild game infected with the larvae of a species of roundworm Trichinella spiralis, commonly called the trichina worm. There are eight Trichinella species; five are...

    . Was killed by having medicine shoved down her throat, causing her to explode.
  • Shane (Danny Cooksey
    Danny Cooksey
    Danny Cooksey is an American singer, actor and voice actor. He has been in show business since he was very young and is best remembered for playing the roles of Sam McKinney on the last years of the TV show Diff'rent Strokes and Robert "Bobby" Budnick on the Nickelodeon program, Salute Your...

    ) - A hormone leader of a testosterone
    Testosterone
    Testosterone is a steroid hormone from the androgen group and is found in mammals, reptiles, birds, and other vertebrates. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands...

     gang that once tied up Mayor Spryman and took control over the Brain, turning common sense off and transforming Hector into a bad kid.
  • Stickety (Rob Paulsen
    Rob Paulsen
    Robert Fredrick "Rob" Paulsen III , sometimes credited as Rob Paulson, is an American voice actor, best known as the voice behind Raphael from the 1987 cartoon of Teenage Mutant Ninja Turtles, Yakko Warner and Dr...

    ) - A sticky, bad cholesterol beatnik
    Beatnik
    Beatnik was a media stereotype of the 1950s and early 1960s that displayed the more superficial aspects of the Beat Generation literary movement of the 1950s and violent film images, along with a cartoonish depiction of the real-life people and the spiritual quest in Jack Kerouac's autobiographical...

     who kidnaps a bunch of fat cell children in an attempt to clog Hector's artery. He sees what he does not as crimes but as art.
  • Cryo (Susan Silo
    Susan Silo
    Susan Silo is an American actress and voice actress.-Early life and career:She was born in New York City, New York. Her acting career started in television on an episode of The Jack Benny Show. Silo also co-starred with Larry Blyden, Dawn Nickerson, and Diahn Williams in the NBC sitcom Harry's...

    ) - A virus that once tried to give Hector hypothermia
    Hypothermia
    Hypothermia is a condition in which core temperature drops below the required temperature for normal metabolism and body functions which is defined as . Body temperature is usually maintained near a constant level of through biologic homeostasis or thermoregulation...

    , despite the fact that hypothermia is when the core temperatures of the body decrease to a critical level. Therefore, it is not a disease. She has the ability to fire freezing blasts from her elbows. She was eventually destroyed when struck by a nerve impulse from Hector's spine.
  • Pb (Jeff Bennett
    Jeff Bennett
    Jeffrey Glenn "Jeff" Bennett is an American voice actor and musician, listed "among the top names in the voice-over field", best known as the voice of Johnny Bravo in the series of the same name...

    ) - Pb is the leader of the Lead
    Lead
    Lead is a main-group element in the carbon group with the symbol Pb and atomic number 82. Lead is a soft, malleable poor metal. It is also counted as one of the heavy metals. Metallic lead has a bluish-white color after being freshly cut, but it soon tarnishes to a dull grayish color when exposed...

     Head gang. He was from a lead-painted shed that was painted in the 1960's, before 1974, when the government banned lead in paint. When Hector sniffed some paint dust, Pb and his boys infect Hector. But thanks to Ozzy, Drix, and the Supplements, the Lead Heads were dropped in the bladder
    Bladder
    Bladder usually refers to an anatomical hollow organBladder may also refer to:-Biology:* Urinary bladder in humans** Urinary bladder ** Bladder control; see Urinary incontinence** Artificial urinary bladder, in humans...

    , and flushed out of Hector.
  • Mitosis Jones (Phil LaMarr
    Phil LaMarr
    Phillip "Phil" LaMarr is an American actor, comedian and voice actor. One of the original cast members on the sketch comedy series MADtv, he is also known for his small, but memorable role as Marvin in Pulp Fiction...

    )- Ozzy's evil and mutated clone who understands that due to his mutation, the city of Hector will reject him. So he plans to take Ozzy's place on the iodine detail and steal it, and without the iodine, Hector cannot grow. At the end of the episode, Mitosis Jones was rejected and lived in the body of Uno, Hector's pet dog, where he was happy.
  • Billy Bob Bile (Frank Welker
    Frank Welker
    Franklin Wendell "Frank" Welker is an American actor who specializes in voice acting and has contributed character voices and other vocal effects to American television and motion pictures.-Acting career:...

    ) - A stereotypical Hillbilly
    Hillbilly
    Hillbilly is a term referring to certain people who dwell in rural, mountainous areas of the United States, primarily Appalachia but also the Ozarks. Owing to its strongly stereotypical connotations, the term is frequently considered derogatory, and so is usually offensive to those Americans of...

     and owner of an appendix hotel who was causing detours which resulted in Hector's appendix almost bursting. Only a quick trip to a hospital saved Hector's life and removed Billy's hotel. Billy attempted to return to civilization, only to cause Ozzy and Drix to slap cuffs on his wrists. He tries to escape, only to take a trip to the small intestine.

Season 1: 2002-2003

# Title Original airdate Production code


Season 2: 2003-2004

# Title Original airdate Production code

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