Outer nuclear layer
Encyclopedia
The outer nuclear layer (or layer of outer granules or external nuclear layer), is one of the layers of the vertebrate retina
Retina
The vertebrate retina is a light-sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera. Light striking the retina initiates a cascade of chemical and electrical...

, the light-detecting portion of the eye. Like the inner nuclear layer
Inner nuclear layer
The inner nuclear layer or layer of inner granules is made up of a number of closely packed cells, of which there are three varieties, viz.: bipolar cells, horizontal cells, and amacrine cells.-Bipolar cells:...

, the outer nuclear layer contains several strata of oval nuclear bodies; they are of two kinds, viz.: rod and cone granules, so named on account of their being respectively connected with the rods and cones of the next layer.

Rod granules

The spherical rod granules are much the more numerous, and are placed at different levels throughout the layer.

Their nuclei present a peculiar cross-striped appearance, and prolonged from either extremity of each cell is a fine process; the outer process is continuous with a single rod of the layer of rods and cones; the inner ends in the outer plexiform layer in an enlarged extremity, and is imbedded in the tuft into which the outer processes of the rod bipolar cells break up.

In its course it presents numerous varicosities.

Cone granules

The stem-like cone granules, fewer in number than the rod granules, are placed close to the membrana limitans externa, through which they are continuous with the cones of the layer of rods and cones.

They do not present any cross-striation, but contain a pyriform nucleus, which almost completely fills the cell.

From the inner extremity of the granule a thick process passes into the outer plexiform layer, and there expands into a pyramidal enlargement or foot plate, from which are given off numerous fine fibrils, that come in contact with the outer processes of the cone bipolars.
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